Search Results for compound

Matched treatment: … reverse peripheral ischemia secondary to vasoconstriction and for the treatment of hypertension …
Matched description: … Cytochalasins are mycotoxins that have the ability to bind to actin filaments and block ... polymerization and the elongation of actin. As a result, they can change cellular morphology, inhibit ... cellular processes such as cell division, and cause cells to undergo apoptosis. Cytochalasins also have the …

Matched description: … Penicillic acid is a mycotoxin produced by several species of Aspergillus and Penicillium. It has ... antibiotic activity and is cytotoxic, hepatotoxic, and carcinogenic. Penicillic acid is a human …

Matched symptoms: … kidneys, the lungs and the pancreas, followed by coma and death. Kashin-Beck disease is characterized by ... joint pain, with restriction of movement and joint enlargement. (A3077) …
Matched treatment: … Kashin-Beck disease cannot be cured but can be treated with physical therapy and corrective surgery …
Matched description: … in contaminated cereal crops and is known to be a lethal food contaminant to fowl as well as a cause of Kashin-Beck disease in humans. (L1969, A3075) …

Matched symptoms: … heart rate), dilated pupils and as respiratory distress. …
Matched description: … member of marine polycyclic ethers to be structurally elucidated and one of the most potent neurotoxins ... stereocenters, which contains six-, seven-, and eight-membered ether rings, three carbon-carbon double ... bonds, one hydroxyl group, and two carbonyl groups (A3250). …

Matched symptoms: … Symptoms of low dose exposure include excessive salivation and eye-watering. Acute dose symptoms ... include severe nausea/vomiting, salivation, sweating, bradycardia, hypotension, collapse, and ... convulsions. Increasing muscle weakness is a possibility and may result in death if respiratory muscles are …
Matched treatment: … bicarbonate. For skin contact, the skin should be washed with soap and water. If the compound has entered ... , atropine and/or pralidoxime should be administered. Anti-cholinergic drugs work to counteract the ... effects of excess acetylcholine and reactivate AChE. Atropine can be used as an antidote in …
Matched description: … of aromatic compounds and are often readily made from reactive aromatic compounds with electron ... -donating substituents such as phenols and catechols, which increase the nucleophilicity of the ring and ... transport chains such as those in photosynthesis (plastoquinone, phylloquinone), and aerobic …

Matched symptoms: … Symptoms include eye irritation, tearing, burning sensation on the nose and throat, rhinorrhoea ... , excess salivation, constricting sensations in the chest, sneezing, coughing, and stinging or burning sensations in exposed skin. …
Matched description: … substance that dissolves other active substances and that easily evaporates) and 2-chlorobenzalmalononitrile, which is a solid compound at room temperature. …

Matched symptoms: … Acute exposure to PAHs causes irritation and inflammation of the skin and lung tissue. (A10) …

Matched symptoms: … Dust has been found irritating to the nose and throat. Skin or eye contact can cause irritation of ... initial hyperactivity followed by hypoactivity, neuromuscular weakness, and convulsions. Headache can …
Matched carcinogenicity: … Not directly listed by IARC, but related polychlorophenols are discussed, and combined exposures to …
Matched treatment: … In case of oral exposure, dilution may enhance absorption of phenol and should be avoided, but ... . Following inhalation exposure, move patient to fresh air. Monitor for respiratory distress, and if cough ... pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with inhaled beta2 …
Matched description: … medicinal taste and odor, and small amounts can be tasted in water. (L159) …

Matched symptoms: … pain), skin discoloration (pink cheeks, fingertips and toes), edema (swelling), and desquamation (dead skin peels off in layers). (A5) …
Matched treatment: … Mercury poisoning is treated by immediate decontamination and chelation therapy using DMSA, DMPS, DPCN, or dimercaprol. (A7) …
Matched description: … solubility in water. It is most often used as a laboratory reagent, and occasionally used to form amalgams with metals. …

Matched symptoms: … contact dermatitis, which is characterized by irritation and rashes. Ingesting large amounts of cobalt may cause nausea and vomiting. (L2090) …
Matched description: … use of cyanide in the purification procedures), hydroxocobalamin and the two coenzyme forms of B12 ... , methylcobalamin (MeB12) and 5-deoxyadenosylcobalamin (adenosylcobalamin - AdoB12). In a more specific ... principal B12 form used for foods and in nutritional supplements. B12 cannot be made by plants or by animals …

Matched symptoms: … Cough, shortness of breath and sore throat can result from inhalation of 2-chlorophenol. These ... symptoms may be delayed. Abdominal pain, drowsiness, weakness, and convulsions can result from ingestion ... , and blurred vision, while dermal contact can lead to redness and pain of the skin. Moreover, the …
Matched treatment: … and assist ventilation as required. Treat bronchospasm with inhaled beta2 agonist and oral or …

Matched symptoms: … twitching, reduced energy, and changes in awareness can result from inhalation or ingestion of large …
Matched treatment: … Following oral exposure, the treatment is symptomatic and supportive and includes monitoring for ... irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat ... bronchospasm with inhaled beta2 agonist and oral or parenteral corticosteroids. In case of eye exposure …
Matched description: … moths, flies, beetles, and other insects. It is used on vegetable crops, tree fruit, and nut crops ... , is less chronically toxic, and is a more powerful insecticide. The compound contains a much higher ... percentage of the one insecticidally active isomer (84% for esfenvalerate and 22% for fenvalerate). A …

Matched symptoms: … Symptoms of nickel poisoning include headache, nausea, vomiting, dizziness, irritability, and ... difficulty sleeping, followed by chest pains, sweating, rapid heart beat, and a dry cough. (L42) …
Matched treatment: … Excess exposure to nickel is usually handled by preventing further exposure and symptomatic …
Matched description: … limonite, garnierite, and pentlandite. Nickel has a biological role and is found in certain enzymes ... , including urease, hydrogenase, methylcoenzyme M reductase, and carbon monoxide dehydrogenase. (L40, L41) …

Matched symptoms: … Inhalation of vanadium causes lung irritation, coughing, wheezing, chest pain, runny nose, and a sore throat. (L837) …
Matched description: … protein kinase B (PKB/Akt) and glycogen synthase kinase-3 (GSK3), as well as inhibit tyrosine phosphatase ... symbol V and atomic number 23. The element usually combines with other elements such as oxygen ... , sodium, sulfur, or chloride, and occurs naturally in about 65 different minerals and in fossil fuel …

Matched symptoms: … Cyanide poisoning is identified by rapid, deep breathing and shortness of breath, general weakness ... , giddiness, headaches, vertigo, confusion, convulsions/seizures and eventually loss of consciousness. (L96, L97) …
Matched treatment: … Antidotes to cyanide poisoning include hydroxocobalamin and sodium nitrite, which release the ... cyanide from the cytochrome system, and rhodanase, which is an enzyme occurring naturally in mammals that …
Matched description: … Benzeneacetonitrile is found in garden cress. Benzeneacetonitrile is isolated from oil of garden cress (Lepidium sativum) and other plant oils. …

Matched symptoms: … Causes severe eye and skin burns. Irritating to eyes, skin, and respiratory system. Acute exposure ... (ingestion or inhalation) can lead to coma, nausea, vomiting, and metabolic acidosis may occur. …
Matched treatment: … cold running water for at least 15 minutes, followed by thorough washing with soap and water. If ... necessary, the person should shower and change contaminated clothing and shoes, and then must seek …
Matched description: … a pleasant aromatic odour. p-Xylyl bromide is highly toxic, irritant and lachrymatory, and has been …

Matched description: … present in the liver and kidney and is found in mushrooms, spinach, yeast, green leaves, and grasses ... (poaceae). Folic acid, being biochemically inactive, is converted to tetrahydrofolic acid and ... purine and thymidylate nucleic acids, interconvert amino acids, methylated tRNA, and generate and use …

Matched symptoms: … In overdosage, some patients exhibit insomnia, restlessness and anxiety, progressing in severe ... cases to agitation, mental confusion and incoherence. Hypotension, dizziness, weakness and drowsiness ... may occur, progressing in severe cases to extreme dizziness and shock. A few patients have displayed …
Matched treatment: … and steps to counteract specific symptoms as they occur, since MAO inhibition may persist. External …
Matched description: … inhibitor is effective in the treatment of major depression, dysthymic disorder, and atypical ... depression. It also is useful in panic and phobic disorders. (From AMA Drug Evaluations Annual, 1994, p311) …

Matched symptoms: … swallowing, dry mouth, extreme sleepiness, fever, intestinal blockage, irregular heart rate, low blood pressure, and restlessness. …
Matched treatment: … Treatment is essentially symptomatic and supportive. Early gastric lavage is helpful. Keep patient ... under observation and maintain an open airway, since involvement of the extrapyramidal mechanism may ... produce dysphagia and respiratory difficulty in severe overdosage. Do not attempt to induce emesis …
Matched description: … phenothiazine with actions similar to chlorpromazine. It is used as an antipsychotic and an antiemetic ... . [PubChem]Trifluoperazine blocks postsynaptic mesolimbic dopaminergic D1 and D2 receptors in the brain ... ; depresses the release of hypothalamic and hypophyseal hormones and is believed to depress the reticular …

Matched symptoms: … , nausea and vomiting, skin rash, swelling of the feet or lower legs, unusual tiredness or weakness, and yellow eyes or skin. (L1536) …
Matched description: … conversion of lanosterol to ergosterol. This results in inhibition of ergosterol synthesis and ... , inhibition of purine uptake, and impairment of triglyceride and/or phospholipid biosynthesis ... . Ketoconazole can also inhibit the synthesis of thromboxane and sterols such as aldosterone, cortisol, and testosterone. …

Matched symptoms: … -depressant agent. Signs and symptoms of overdose effects of CNS depressants can be expected to present as …
Matched description: … complex and modulation of the GABA_BZ receptor chloride channel macromolecular complex. Both ... zopiclone and benzodiazepines act indiscriminately at the benzodiazepine binding site on α1 ... , α2, α3 and α5 GABA_A containing receptors as full agonists causing an …
Matched compound_type: … Hypnotic and Sedative …

Matched symptoms: … Acute overdoses may produce nausea, vomiting, and CNS depression including coma with respiratory ... depression. Levels greater than 40 µg/mL have caused toxicity and coma has been seen at levels of 150 µg/mL. …
Matched treatment: … , or convulsing) or gastric lavage, activated charcoal, cathartics, and general supportive measures ... diuresis and exchange transfusions are ineffective. (L1712) …
Matched description: … into excitable cells and are also involved in a variety of calcium-dependent processes, including ... division and cell death. The isoform alpha-1G gives rise to T-type calcium currents. T-type calcium ... channels belong to the low-voltage activated (LVA) group and are strongly blocked by mibefradil. A …

Matched symptoms: … to pulmonary edema, bloody sputum, and bronchial pneumonia. At high amounts, central nervous system ... depression may also occur, with symptoms such as weakness, dizziness, slow and shallow respiration ... , unconsciousness, and convulsions. Petroleum distillates are also irritating to the skin. (A594) …
Matched treatment: … Treatment is mainly symptomatic and supportive. Gastric lavage, emesis, and the administration of …
Matched description: … an aromatic hydrocarbon. It is a constituent of crude oil and refined fuels. It is a flammable ... synthesis of other industrially important chemicals such as phenol and acetone. Isopropylbenzene has been shown to exhibit catabolic function (A7843). …

Matched symptoms: … Orally and parenterally administered clindamycin has been associated with severe colitis ... results in absorption of the antibiotic from the skin surface. Diarrhea, bloody diarrhea, and colitis ... (including pseudomembranous colitis) have been reported with the use of topical and systemic clindamycin. …
Matched description: … bacterial 50S ribosomal subunits. It may be bacteriostatic or bactericidal depending on the organism and drug concentration. …

Matched description: … is an antagonist at both the alpha-1 adrenergic receptor and the 5-HT2A serotonin receptor, and ... blocks both the behavioural and physiological effects of MDMA in animals. …