AF-710B (CHEM134260)
| Record Information | |||||||||
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| Version | 1.0 | ||||||||
| Creation Date | 2026-04-14 21:06:38 UTC | ||||||||
| Update Date | 2026-05-14 20:00:26 UTC | ||||||||
| Accession Number | CHEM134260 | ||||||||
| Identification | |||||||||
| Common Name | AF-710B | ||||||||
| Class | Small Molecule | ||||||||
| Description | AF-710B is an organic compound with the formula C20H27N3OS and an average molecular weight of 357.52 g/mol. AF-710B belongs to the tryptamines and derivatives, a subclass of indoles and derivatives within the organic compounds. Within the superclass of organoheterocyclic compounds, this substance is recorded as having two protein targets. It acts as an agonist of the Sigma non-opioid intracellular receptor 1 (SIGMAR1) and the Muscarinic acetylcholine receptor M1 (CHRM1). | ||||||||
| Contaminant Sources | Not Available | ||||||||
| Contaminant Type | Not Available | ||||||||
| Chemical Structure |  | ||||||||
| Synonyms | Not Available | ||||||||
| Chemical Formula | C20H27N3OS | ||||||||
| Average Molecular Mass | 357.520 g/mol | ||||||||
| Monoisotopic Mass | 357.187 g/mol | ||||||||
| CAS Registry Number | 1235733-73-9 | ||||||||
| IUPAC Name | 1-{2,8-dimethyl-1-thia-3,8-diazaspiro[4.5]decan-3-yl}-3-(1H-indol-3-yl)propan-1-one | ||||||||
| Traditional Name | Not Available | ||||||||
| SMILES | CC1SC2(CN1C(=O)CCC1=CNC3=C1C=CC=C3)CCN(C)CC2 | ||||||||
| InChI Identifier | InChI=1S/C20H27N3OS/c1-15-23(14-20(25-15)9-11-22(2)12-10-20)19(24)8-7-16-13-21-18-6-4-3-5-17(16)18/h3-6,13,15,21H,7-12,14H2,1-2H3 | ||||||||
| InChI Key | XWMHYQATSBWUNT-UHFFFAOYSA-N | ||||||||
| Chemical Taxonomy | |||||||||
| Classification | Not classified | ||||||||
| Biological Properties | |||||||||
| Status | Detected and Not Quantified | ||||||||
| Origin | Not Available | ||||||||
| Cellular Locations | Not Available | ||||||||
| Biofluid Locations | Not Available | ||||||||
| Tissue Locations | Not Available | ||||||||
| Pathways | Not Available | ||||||||
| Applications | Not Available | ||||||||
| Biological Roles | Not Available | ||||||||
| Chemical Roles | Not Available | ||||||||
| Physical Properties | |||||||||
| State | Not Available | ||||||||
| Appearance | Not Available | ||||||||
| Experimental Properties |
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| Predicted Properties | Not Available | ||||||||
| Spectra | |||||||||
| Spectra |
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| Toxicity Profile | |||||||||
| Route of Exposure | Not Available | ||||||||
| Mechanism of Toxicity | Not Available | ||||||||
| Metabolism | Not Available | ||||||||
| Toxicity Values | Not Available | ||||||||
| Lethal Dose | Not Available | ||||||||
| Carcinogenicity (IARC Classification) | Not Available | ||||||||
| Uses/Sources | Not Available | ||||||||
| Minimum Risk Level | Not Available | ||||||||
| Health Effects | Not Available | ||||||||
| Symptoms | Not Available | ||||||||
| Treatment | Not Available | ||||||||
| Concentrations | |||||||||
| Not Available | |||||||||
| External Links | |||||||||
| Identifiers | Not Available | ||||||||
| References | |||||||||
| Synthesis Reference | Not Available | ||||||||
| MSDS | Not Available | ||||||||
| General References | Not Available | ||||||||
