A-674563 (CHEM130236)
| Record Information | |||||||||
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| Version | 1.0 | ||||||||
| Creation Date | 2026-04-14 17:26:38 UTC | ||||||||
| Update Date | 2026-05-14 18:58:38 UTC | ||||||||
| Accession Number | CHEM130236 | ||||||||
| Identification | |||||||||
| Common Name | A-674563 | ||||||||
| Class | Small Molecule | ||||||||
| Description | A-674563 is an organic compound with the formula C22H22N4O and an average molecular weight of 358.44 g/mol. A-674563 belongs to the phenethylamines, a subclass of benzene and substituted derivatives within the organic compounds. This compound is further classified as a member of the benzenoids superclass. In terms of biological activity, A-674563 is associated with three recorded protein targets. It acts as an inhibitor of the cAMP-dependent protein kinase catalytic subunit alpha (PRKACA), the cAMP-dependent protein kinase inhibitor alpha (PKIA), and the RAC-alpha serine/threonine-protein kinase (AKT1). | ||||||||
| Contaminant Sources | Not Available | ||||||||
| Contaminant Type | Not Available | ||||||||
| Chemical Structure |  | ||||||||
| Synonyms | Not Available | ||||||||
| Chemical Formula | C22H22N4O | ||||||||
| Average Molecular Mass | 358.436 g/mol | ||||||||
| Monoisotopic Mass | 358.179 g/mol | ||||||||
| CAS Registry Number | 552325-73-2 | ||||||||
| IUPAC Name | (2S)-1-{[5-(3-methyl-1H-indazol-5-yl)pyridin-3-yl]oxy}-3-phenylpropan-2-amine | ||||||||
| Traditional Name | Not Available | ||||||||
| SMILES | CC1=NNC2=C1C=C(C=C2)C1=CC(OC[C@@H](N)CC2=CC=CC=C2)=CN=C1 | ||||||||
| InChI Identifier | InChI=1S/C22H22N4O/c1-15-21-11-17(7-8-22(21)26-25-15)18-10-20(13-24-12-18)27-14-19(23)9-16-5-3-2-4-6-16/h2-8,10-13,19H,9,14,23H2,1H3,(H,25,26)/t19-/m0/s1 | ||||||||
| InChI Key | BPNUQXPIQBZCMR-IBGZPJMESA-N | ||||||||
| Chemical Taxonomy | |||||||||
| Classification | Not classified | ||||||||
| Biological Properties | |||||||||
| Status | Detected and Not Quantified | ||||||||
| Origin | Not Available | ||||||||
| Cellular Locations | Not Available | ||||||||
| Biofluid Locations | Not Available | ||||||||
| Tissue Locations | Not Available | ||||||||
| Pathways | Not Available | ||||||||
| Applications | Not Available | ||||||||
| Biological Roles | Not Available | ||||||||
| Chemical Roles | Not Available | ||||||||
| Physical Properties | |||||||||
| State | Not Available | ||||||||
| Appearance | Not Available | ||||||||
| Experimental Properties |
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| Predicted Properties | Not Available | ||||||||
| Spectra | |||||||||
| Spectra |
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| Toxicity Profile | |||||||||
| Route of Exposure | Not Available | ||||||||
| Mechanism of Toxicity | Not Available | ||||||||
| Metabolism | Not Available | ||||||||
| Toxicity Values | Not Available | ||||||||
| Lethal Dose | Not Available | ||||||||
| Carcinogenicity (IARC Classification) | Not Available | ||||||||
| Uses/Sources | Not Available | ||||||||
| Minimum Risk Level | Not Available | ||||||||
| Health Effects | Not Available | ||||||||
| Symptoms | Not Available | ||||||||
| Treatment | Not Available | ||||||||
| Concentrations | |||||||||
| Not Available | |||||||||
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| Identifiers | Not Available | ||||||||
| References | |||||||||
| Synthesis Reference | Not Available | ||||||||
| MSDS | Not Available | ||||||||
| General References | Not Available | ||||||||
