Cariprazine (CHEM129643)
| Record Information | |||||||||
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| Version | 1.0 | ||||||||
| Creation Date | 2026-04-14 15:57:53 UTC | ||||||||
| Update Date | 2026-05-14 18:17:27 UTC | ||||||||
| Accession Number | CHEM129643 | ||||||||
| Identification | |||||||||
| Common Name | Cariprazine | ||||||||
| Class | Small Molecule | ||||||||
| Description | Cariprazine is an organic compound with the chemical formula C21H32Cl2N4O and an average molecular weight of 427.41 g/mol. Cariprazine belongs to the piperazines, a subclass of diazinanes within the organic compounds. It is classified as an organoheterocyclic compound. This compound is found in or released from one recorded source: healthcare, pharmaceuticals & veterinary products, specifically as an antipsychotic. The recorded route of exposure is oral. Cariprazine interacts with eight recorded protein targets. It acts as an antagonist or partial agonist of the D(2) dopamine receptor (DRD2), the D(3) dopamine receptor (DRD3), the 5-hydroxytryptamine receptor 1A (HTR1A), and the 5-hydroxytryptamine receptor 2B (HTR2B). Additionally, it targets four other proteins. | ||||||||
| Contaminant Sources | Not Available | ||||||||
| Contaminant Type | Not Available | ||||||||
| Chemical Structure |  | ||||||||
| Synonyms | Not Available | ||||||||
| Chemical Formula | C21H32Cl2N4O | ||||||||
| Average Molecular Mass | 427.410 g/mol | ||||||||
| Monoisotopic Mass | 426.195 g/mol | ||||||||
| CAS Registry Number | 839712-12-8 | ||||||||
| IUPAC Name | 3,3-dimethyl-1-[(1r,4r)-4-{2-[4-(2,3-dichlorophenyl)piperazin-1-yl]ethyl}cyclohexyl]urea | ||||||||
| Traditional Name | Not Available | ||||||||
| SMILES | CN(C)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)C2=C(Cl)C(Cl)=CC=C2)CC1 | ||||||||
| InChI Identifier | InChI=1S/C21H32Cl2N4O/c1-25(2)21(28)24-17-8-6-16(7-9-17)10-11-26-12-14-27(15-13-26)19-5-3-4-18(22)20(19)23/h3-5,16-17H,6-15H2,1-2H3,(H,24,28)/t16-,17- | ||||||||
| InChI Key | KPWSJANDNDDRMB-QAQDUYKDSA-N | ||||||||
| Chemical Taxonomy | |||||||||
| Classification | Not classified | ||||||||
| Biological Properties | |||||||||
| Status | Detected and Not Quantified | ||||||||
| Origin | Not Available | ||||||||
| Cellular Locations | Not Available | ||||||||
| Biofluid Locations | Not Available | ||||||||
| Tissue Locations | Not Available | ||||||||
| Pathways | Not Available | ||||||||
| Applications | Not Available | ||||||||
| Biological Roles | Not Available | ||||||||
| Chemical Roles | Not Available | ||||||||
| Physical Properties | |||||||||
| State | Not Available | ||||||||
| Appearance | Not Available | ||||||||
| Experimental Properties |
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| Predicted Properties | Not Available | ||||||||
| Spectra | |||||||||
| Spectra |
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| Toxicity Profile | |||||||||
| Route of Exposure | Not Available | ||||||||
| Mechanism of Toxicity | Not Available | ||||||||
| Metabolism | Not Available | ||||||||
| Toxicity Values | Not Available | ||||||||
| Lethal Dose | Not Available | ||||||||
| Carcinogenicity (IARC Classification) | Not Available | ||||||||
| Uses/Sources | Not Available | ||||||||
| Minimum Risk Level | Not Available | ||||||||
| Health Effects | Not Available | ||||||||
| Symptoms | Not Available | ||||||||
| Treatment | Not Available | ||||||||
| Concentrations | |||||||||
| Not Available | |||||||||
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| Identifiers | Not Available | ||||||||
| References | |||||||||
| Synthesis Reference | Not Available | ||||||||
| MSDS | Not Available | ||||||||
| General References | Not Available | ||||||||
