Telotristat Ethyl (CHEM102996)
| Record Information | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Version | 1.0 | |||||||||
| Creation Date | 2026-04-05 13:39:19 UTC | |||||||||
| Update Date | 2026-08-22 07:19:27 UTC | |||||||||
| Accession Number | CHEM102996 | |||||||||
| Identification | ||||||||||
| Common Name | Telotristat Ethyl | |||||||||
| Class | Small Molecule | |||||||||
| Description | Telotristat Ethyl is an organic compound with the formula C27H26ClF3N6O3. Telotristat Ethyl belongs to the amino acids, peptides, and analogues, a subclass of carboxylic acids and derivatives within the organic compounds. With an average molecular weight of 574.99 g/mol, Telotristat Ethyl is a heavy molecule. This compound acts as an antagonist of two protein targets: Tryptophan 5-hydroxylase 1 (TPH1) and Tryptophan 5-hydroxylase 2 (TPH2). | |||||||||
| Contaminant Sources | Not Available | |||||||||
| Contaminant Type | Not Available | |||||||||
| Chemical Structure |  | |||||||||
| Synonyms | Not Available | |||||||||
| Chemical Formula | C27H26ClF3N6O3 | |||||||||
| Average Molecular Mass | 574.990 g/mol | |||||||||
| Monoisotopic Mass | 574.171 g/mol | |||||||||
| CAS Registry Number | 1033805-22-9 | |||||||||
| IUPAC Name | ethyl (2S)-2-amino-3-(4-{2-amino-6-[(1R)-1-[4-chloro-2-(3-methyl-1H-pyrazol-1-yl)phenyl]-2,2,2-trifluoroethoxy]pyrimidin-4-yl}phenyl)propanoate | |||||||||
| Traditional Name | Not Available | |||||||||
| SMILES | CCOC(=O)[C@@H](N)CC1=CC=C(C=C1)C1=NC(N)=NC(O[C@H](C2=CC=C(Cl)C=C2N2C=CC(C)=N2)C(F)(F)F)=C1 | |||||||||
| InChI Identifier | InChI=1S/C27H26ClF3N6O3/c1-3-39-25(38)20(32)12-16-4-6-17(7-5-16)21-14-23(35-26(33)34-21)40-24(27(29,30)31)19-9-8-18(28)13-22(19)37-11-10-15(2)36-37/h4-11,13-14,20,24H,3,12,32H2,1-2H3,(H2,33,34,35)/t20-,24+/m0/s1 | |||||||||
| InChI Key | MDSQOJYHHZBZKA-GBXCKJPGSA-N | |||||||||
| Chemical Taxonomy | ||||||||||
| Classification | Not classified | |||||||||
| Biological Properties | ||||||||||
| Status | Detected and Not Quantified | |||||||||
| Origin | Not Available | |||||||||
| Cellular Locations | Not Available | |||||||||
| Biofluid Locations | Not Available | |||||||||
| Tissue Locations | Not Available | |||||||||
| Pathways |
| |||||||||
| Applications | Not Available | |||||||||
| Biological Roles | Not Available | |||||||||
| Chemical Roles | Not Available | |||||||||
| Physical Properties | ||||||||||
| State | Not Available | |||||||||
| Appearance | Not Available | |||||||||
| Experimental Properties |
| |||||||||
| Predicted Properties | Not Available | |||||||||
| Spectra | ||||||||||
| Spectra |
| |||||||||
| Toxicity Profile | ||||||||||
| Route of Exposure | Not Available | |||||||||
| Mechanism of Toxicity | Not Available | |||||||||
| Metabolism | Not Available | |||||||||
| Toxicity Values | Not Available | |||||||||
| Lethal Dose | Not Available | |||||||||
| Carcinogenicity (IARC Classification) | Not Available | |||||||||
| Uses/Sources | Not Available | |||||||||
| Minimum Risk Level | Not Available | |||||||||
| Health Effects | Not Available | |||||||||
| Symptoms | Not Available | |||||||||
| Treatment | Not Available | |||||||||
| Concentrations | ||||||||||
| Not Available | ||||||||||
| External Links | ||||||||||
| Identifiers | Not Available | |||||||||
| References | ||||||||||
| Synthesis Reference | Not Available | |||||||||
| MSDS | Not Available | |||||||||
| General References | Not Available | |||||||||
