Loteprednol (CHEM077392)
| Record Information | |||||||||
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| Version | 1.0 | ||||||||
| Creation Date | 2026-04-04 18:14:31 UTC | ||||||||
| Update Date | 2026-08-21 19:28:03 UTC | ||||||||
| Accession Number | CHEM077392 | ||||||||
| Identification | |||||||||
| Common Name | Loteprednol | ||||||||
| Class | Small Molecule | ||||||||
| Description | Loteprednol is an organic compound with the formula C21H27Cl1O5 and an average molecular weight of 394.89 g/mol. Loteprednol belongs to the androstane steroids, a subclass of steroids and steroid derivatives within the organic compounds. It acts as an agonist of the Glucocorticoid receptor (NR3C1). This substance has been found in or released from household cleaning and consumer products, specifically other smoking requisites. | ||||||||
| Contaminant Sources | Not Available | ||||||||
| Contaminant Type | Not Available | ||||||||
| Chemical Structure |  | ||||||||
| Synonyms | Not Available | ||||||||
| Chemical Formula | C21H27Cl1O5 | ||||||||
| Average Molecular Mass | 394.890 g/mol | ||||||||
| Monoisotopic Mass | 394.155 g/mol | ||||||||
| CAS Registry Number | 129260-79-3 | ||||||||
| IUPAC Name | chloromethyl 11,17-dihydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-17-carboxylate | ||||||||
| Traditional Name | Not Available | ||||||||
| SMILES | C[C@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)C=C[C@]34C)[C@@H]1CC[C@]2(O)C(=O)OCCl | ||||||||
| InChI Identifier | InChI=1S/C21H27ClO5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,18(25)27-11-22)20(15,2)10-16(24)17(14)19/h5,7,9,14-17,24,26H,3-4,6,8,10-11H2,1-2H3 | ||||||||
| InChI Key | YPZVAYHNBBHPTO-UHFFFAOYSA-N | ||||||||
| Chemical Taxonomy | |||||||||
| Classification | Not classified | ||||||||
| Biological Properties | |||||||||
| Status | Detected and Not Quantified | ||||||||
| Origin | Not Available | ||||||||
| Cellular Locations | Not Available | ||||||||
| Biofluid Locations | Not Available | ||||||||
| Tissue Locations | Not Available | ||||||||
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| Applications | Not Available | ||||||||
| Biological Roles | Not Available | ||||||||
| Chemical Roles | Not Available | ||||||||
| Physical Properties | |||||||||
| State | Not Available | ||||||||
| Appearance | Not Available | ||||||||
| Experimental Properties |
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| Predicted Properties | Not Available | ||||||||
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| Route of Exposure | Not Available | ||||||||
| Mechanism of Toxicity | Not Available | ||||||||
| Metabolism | Not Available | ||||||||
| Toxicity Values | Not Available | ||||||||
| Lethal Dose | Not Available | ||||||||
| Carcinogenicity (IARC Classification) | Not Available | ||||||||
| Uses/Sources | Not Available | ||||||||
| Minimum Risk Level | Not Available | ||||||||
| Health Effects | Not Available | ||||||||
| Symptoms | Not Available | ||||||||
| Treatment | Not Available | ||||||||
| Concentrations | |||||||||
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| Identifiers | Not Available | ||||||||
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| Synthesis Reference | Not Available | ||||||||
| MSDS | Not Available | ||||||||
| General References | Not Available | ||||||||
