Azvudine (CHEM133847)
| Record Information | |||||||||
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| Version | 1.0 | ||||||||
| Creation Date | 2026-04-14 20:47:08 UTC | ||||||||
| Update Date | 2026-08-25 08:47:02 UTC | ||||||||
| Accession Number | CHEM133847 | ||||||||
| Identification | |||||||||
| Common Name | Azvudine | ||||||||
| Class | Small Molecule | ||||||||
| Description | Azvudine is an organic compound with the chemical formula C9H11FN6O4 and an average molecular weight of 286.22 g/mol. Azvudine belongs to the pyrimidines and pyrimidine derivatives, a subclass of diazines within the organic compounds. It is further classified as an organoheterocyclic compound. Regarding its biological activity, three protein targets have been recorded for Azvudine. It acts as an activator and regulator of the ATP-dependent translocase ABCB1, the ATP-binding cassette sub-family C member 2 (ABCC2), and the Broad substrate specificity ATP-binding cassette transporter ABCG2. | ||||||||
| Contaminant Sources | Not Available | ||||||||
| Contaminant Type | Not Available | ||||||||
| Chemical Structure |  | ||||||||
| Synonyms | Not Available | ||||||||
| Chemical Formula | C9H11FN6O4 | ||||||||
| Average Molecular Mass | 286.223 g/mol | ||||||||
| Monoisotopic Mass | 286.083 g/mol | ||||||||
| CAS Registry Number | 1011529-10-4 | ||||||||
| IUPAC Name | 4-amino-1-[(2R,3S,4R,5R)-5-azido-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydropyrimidin-2-one | ||||||||
| Traditional Name | Not Available | ||||||||
| SMILES | NC1=NC(=O)N(C=C1)[C@@H]1O[C@@](CO)(N=[N+]=[N-])[C@@H](O)[C@@H]1F | ||||||||
| InChI Identifier | InChI=1S/C9H11FN6O4/c10-5-6(18)9(3-17,14-15-12)20-7(5)16-2-1-4(11)13-8(16)19/h1-2,5-7,17-18H,3H2,(H2,11,13,19)/t5-,6-,7+,9+/m0/s1 | ||||||||
| InChI Key | KTOLOIKYVCHRJW-XZMZPDFPSA-N | ||||||||
| Chemical Taxonomy | |||||||||
| Classification | Not classified | ||||||||
| Biological Properties | |||||||||
| Status | Detected and Not Quantified | ||||||||
| Origin | Not Available | ||||||||
| Cellular Locations | Not Available | ||||||||
| Biofluid Locations | Not Available | ||||||||
| Tissue Locations | Not Available | ||||||||
| Pathways | Not Available | ||||||||
| Applications | Not Available | ||||||||
| Biological Roles | Not Available | ||||||||
| Chemical Roles | Not Available | ||||||||
| Physical Properties | |||||||||
| State | Not Available | ||||||||
| Appearance | Not Available | ||||||||
| Experimental Properties |
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| Predicted Properties | Not Available | ||||||||
| Spectra | |||||||||
| Spectra |
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| Toxicity Profile | |||||||||
| Route of Exposure | Not Available | ||||||||
| Mechanism of Toxicity | Not Available | ||||||||
| Metabolism | Not Available | ||||||||
| Toxicity Values | Not Available | ||||||||
| Lethal Dose | Not Available | ||||||||
| Carcinogenicity (IARC Classification) | Not Available | ||||||||
| Uses/Sources | Not Available | ||||||||
| Minimum Risk Level | Not Available | ||||||||
| Health Effects | Not Available | ||||||||
| Symptoms | Not Available | ||||||||
| Treatment | Not Available | ||||||||
| Concentrations | |||||||||
| Not Available | |||||||||
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| Identifiers | Not Available | ||||||||
| References | |||||||||
| Synthesis Reference | Not Available | ||||||||
| MSDS | Not Available | ||||||||
| General References | Not Available | ||||||||
