Identification Common Name ORP-101 Class Small Molecule Description ORP-101 is an organic compound with the chemical formula C60H84N2O8. ORP-101 belongs to the phenanthrenes and derivatives, a class of benzenoids within the organic compounds. With an average molecular weight of 961.34 g/mol, ORP-101 is a heavy molecule. Regarding its pharmacological activity, the compound acts as an inhibitor of two protein targets: the Kappa-type opioid receptor (OPRK1) and the Mu-type opioid receptor (OPRM1). Contaminant Sources Not Available Contaminant Type Not Available Chemical Structure Synonyms Not Available Chemical Formula C60 H84 N2 O8 Average Molecular Mass 961.338 g/mol Monoisotopic Mass 960.623 g/mol CAS Registry Number 1820753-68-1 IUPAC Name (2S)-2-[(1S,2R,6S,14R,15R,16R)-3-(cyclopropylmethyl)-11-(2-{[(1S,2R,6S,14R,15R,16R)-3-(cyclopropylmethyl)-16-[(2S)-2-hydroxy-3,3-dimethylbutan-2-yl]-15-methoxy-13-oxa-3-azahexacyclo[13.2.2.1^{2,8}.0^{1,6}.0^{6,14}.0^{7,12}]icosa-7(12),8,10-trien-11-yl]oxy}ethoxy)-15-methoxy-13-oxa-3-azahexacyclo[13.2.2.1^{2,8}.0^{1,6}.0^{6,14}.0^{7,12}]icosa-7(12),8,10-trien-16-yl]-3,3-dimethylbutan-2-ol Traditional Name Not Available SMILES [H][C@@]12OC3=C4C(C[C@H]5N(CC6CC6)CC[C@@]14[C@@]51CC[C@@]2(OC)[C@]([H])(C1)[C@](C)(O)C(C)(C)C)=CC=C3OCCOC1=CC=C2C[C@H]3N(CC4CC4)CC[C@]45C2=C1O[C@@]4([H])[C@]1(CC[C@@]35C[C@]1([H])[C@](C)(O)C(C)(C)C)OC InChI Identifier InChI=1S/C60H84N2O8/c1-51(2,3)53(7,63)41-31-55-19-21-59(41,65-9)49-57(55)23-25-61(33-35-11-12-35)43(55)29-37-15-17-39(47(69-49)45(37)57)67-27-28-68-40-18-16-38-30-44-56-20-22-60(66-10,42(32-56)54(8,64)52(4,5)6)50-58(56,46(38)48(40)70-50)24-26-62(44)34-36-13-14-36/h15-18,35-36,41-44,49-50,63-64H,11-14,19-34H2,1-10H3/t41-,42-,43-,44-,49-,50-,53+,54+,55-,56-,57+,58+,59-,60-/m1/s1 InChI Key LEQOVFCHMOTJKU-WJVXOHEGSA-N 
