Record Information |
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Version | 1.0 |
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Creation Date | 2016-05-26 05:53:26 UTC |
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Update Date | 2016-11-09 01:21:20 UTC |
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Accession Number | CHEM035567 |
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Identification |
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Common Name | 5a-Pregnane-3,20-dione |
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Class | Small Molecule |
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Description | A C21-steroid hormone that is 5alpha-pregnane substituted by oxo groups at positions 3 and 20. It is a metabolite of progestrone. |
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Contaminant Sources | |
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Contaminant Type | Not Available |
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Chemical Structure | |
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Synonyms | Value | Source |
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3,20-Allopregnanedione | ChEBI | 3,20-Dioxo-5alpha-pregnane | ChEBI | 5-alpha-Dihydroprogesterone | ChEBI | 5alpha-Dihydroprogesterone | ChEBI | 3,20-Dioxo-5a-pregnane | Generator | 3,20-Dioxo-5α-pregnane | Generator | 5-a-Dihydroprogesterone | Generator | 5-Α-dihydroprogesterone | Generator | 5a-Dihydroprogesterone | Generator | 5Α-dihydroprogesterone | Generator | 5-alpha-Pregnane-3,20-dione | HMDB, MeSH | 5a-Pregnan-3,20-dione | HMDB | 5alpha-Pregnan-3,20-dione | HMDB | 5alpha-Pregnane-3,20-dione | HMDB, MeSH | 5b-Pregnane-3,20-dione | HMDB | 5beta-Pregnane-3,20-dione | HMDB | Allopregnan-3,20-dione | HMDB | Pregnane-3,20-dione | HMDB | 5 alpha Dihydroprogesterone | MeSH, HMDB | 5 beta Pregnane 3,20 dione | MeSH, HMDB | 5 beta-Pregnane-3,20-dione | MeSH, HMDB | 5-beta-Dihydroprogesterone | MeSH, HMDB | 5alpha-DHP | MeSH, HMDB | 3,20-Allopregnanedione, (5beta,13alpha,17alpha)-isomer | MeSH, HMDB | 5 alpha Pregnanedione | MeSH, HMDB | 5alpha DHP | MeSH, HMDB | 5alpha Pregnane 3,20 dione | MeSH, HMDB | 5beta DHP | MeSH, HMDB | 5beta-DHP | MeSH, HMDB | 3,20 Allopregnanedione | MeSH, HMDB | 3,20-Allopregnanedione, (5alpha)-isomer | MeSH, HMDB | 5 alpha Pregnane 3,20 dione | MeSH, HMDB | 5 alpha-Dihydroprogesterone | MeSH, HMDB | 5 alpha-Pregnane-3,20-dione | MeSH, HMDB | 5 beta Dihydroprogesterone | MeSH, HMDB | 5-alpha-Pregnanedione | MeSH, HMDB |
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Chemical Formula | C21H32O2 |
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Average Molecular Mass | 316.478 g/mol |
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Monoisotopic Mass | 316.240 g/mol |
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CAS Registry Number | 566-65-4 |
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IUPAC Name | (1S,2S,7S,10R,11S,14S,15S)-14-acetyl-2,15-dimethyltetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadecan-5-one |
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Traditional Name | 5a-pregnane-3,20-dione |
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SMILES | [H][C@@]12CC[C@H](C(C)=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC[C@@]2([H])CC(=O)CC[C@]12C |
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InChI Identifier | InChI=1S/C21H32O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h14,16-19H,4-12H2,1-3H3/t14-,16-,17+,18-,19-,20-,21+/m0/s1 |
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InChI Key | XMRPGKVKISIQBV-BJMCWZGWSA-N |
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Chemical Taxonomy |
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Description | belongs to the class of organic compounds known as gluco/mineralocorticoids, progestogins and derivatives. These are steroids with a structure based on a hydroxylated prostane moiety. |
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Kingdom | Organic compounds |
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Super Class | Lipids and lipid-like molecules |
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Class | Steroids and steroid derivatives |
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Sub Class | Pregnane steroids |
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Direct Parent | Gluco/mineralocorticoids, progestogins and derivatives |
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Alternative Parents | |
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Substituents | - Progestogin-skeleton
- 20-oxosteroid
- 3-oxo-5-alpha-steroid
- Oxosteroid
- 3-oxosteroid
- Cyclic ketone
- Ketone
- Organic oxygen compound
- Organic oxide
- Hydrocarbon derivative
- Organooxygen compound
- Carbonyl group
- Aliphatic homopolycyclic compound
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Molecular Framework | Aliphatic homopolycyclic compounds |
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External Descriptors | |
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Biological Properties |
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Status | Detected and Not Quantified |
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Origin | Not Available |
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Cellular Locations | Not Available |
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Biofluid Locations | Not Available |
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Tissue Locations | Not Available |
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Pathways | Not Available |
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Applications | Not Available |
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Biological Roles | Not Available |
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Chemical Roles | Not Available |
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Physical Properties |
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State | Not Available |
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Appearance | Not Available |
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Experimental Properties | Property | Value |
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Melting Point | Not Available | Boiling Point | Not Available | Solubility | Not Available |
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Predicted Properties | |
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Spectra |
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Spectra | Spectrum Type | Description | Splash Key | View |
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GC-MS | GC-MS Spectrum - GC-MS (Non-derivatized) | splash10-0umu-9810000000-76ef4cf96a30792f4d73 | Spectrum | GC-MS | GC-MS Spectrum - GC-MS (Non-derivatized) | splash10-0umu-9810000000-7151501afadd028a99ec | Spectrum | GC-MS | GC-MS Spectrum - GC-MS (Non-derivatized) | splash10-0umu-9810000000-76ef4cf96a30792f4d73 | Spectrum | GC-MS | GC-MS Spectrum - GC-MS (Non-derivatized) | splash10-0umu-9810000000-7151501afadd028a99ec | Spectrum | GC-MS | GC-MS Spectrum - GC-EI-TOF (Non-derivatized) | splash10-0f76-4910000000-81546b52d59f9518cb0c | Spectrum | GC-MS | GC-MS Spectrum - GC-EI-TOF (Non-derivatized) | splash10-0f76-4910000000-dbf8c4ca357b5f19f54d | Spectrum | Predicted GC-MS | Predicted GC-MS Spectrum - GC-MS (Non-derivatized) - 70eV, Positive | splash10-0fkj-0391000000-1964b2faffc1ae5ab9b4 | Spectrum | Predicted GC-MS | Predicted GC-MS Spectrum - GC-MS (Non-derivatized) - 70eV, Positive | Not Available | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 10V, Positive | splash10-014i-0159000000-fdffc096796499edd3d4 | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 20V, Positive | splash10-05p2-0492000000-3f8a5badfddf1ced4edf | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 40V, Positive | splash10-052f-2590000000-932901e825351ef60bc4 | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 10V, Negative | splash10-014i-0019000000-8848319d0e10bc22bc8c | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 20V, Negative | splash10-014i-0039000000-04efc7afcedbf957d0ee | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 40V, Negative | splash10-006t-1090000000-259e4f493b06ea76a0d6 | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 10V, Positive | splash10-014j-0069000000-c9fab448f80ee78066da | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 20V, Positive | splash10-0002-0491000000-c1e83a8609698882ba42 | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 40V, Positive | splash10-0f6x-3920000000-1083c653754015836eb2 | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 10V, Negative | splash10-014i-0009000000-be6e06313d0abca8e664 | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 20V, Negative | splash10-014i-0049000000-e44dad0db5aa758e4dd5 | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 40V, Negative | splash10-00ls-0091000000-f15b1c3e520b40f7172b | Spectrum |
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Toxicity Profile |
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Route of Exposure | Not Available |
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Mechanism of Toxicity | Not Available |
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Metabolism | Not Available |
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Toxicity Values | Not Available |
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Lethal Dose | Not Available |
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Carcinogenicity (IARC Classification) | Not Available |
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Uses/Sources | Not Available |
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Minimum Risk Level | Not Available |
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Health Effects | Not Available |
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Symptoms | Not Available |
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Treatment | Not Available |
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Concentrations |
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| Not Available |
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External Links |
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DrugBank ID | Not Available |
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HMDB ID | HMDB0003759 |
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FooDB ID | FDB023222 |
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Phenol Explorer ID | Not Available |
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KNApSAcK ID | Not Available |
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BiGG ID | Not Available |
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BioCyc ID | Not Available |
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METLIN ID | Not Available |
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PDB ID | Not Available |
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Wikipedia Link | 5%CE%B1-Dihydroprogesterone |
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Chemspider ID | 83782 |
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ChEBI ID | 28952 |
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PubChem Compound ID | 92810 |
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Kegg Compound ID | C03681 |
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YMDB ID | Not Available |
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ECMDB ID | M2MDB005075 |
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References |
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Synthesis Reference | Not Available |
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MSDS | Not Available |
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General References | |
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