Record Information |
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Version | 1.0 |
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Creation Date | 2016-05-26 05:12:39 UTC |
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Update Date | 2016-11-09 01:21:11 UTC |
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Accession Number | CHEM034776 |
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Identification |
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Common Name | Tetrahydrobiopterin |
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Class | Small Molecule |
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Description | |
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Contaminant Sources | - FooDB Chemicals
- STOFF IDENT Compounds
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Contaminant Type | Not Available |
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Chemical Structure | |
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Synonyms | Value | Source |
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2-Amino-6-(1,2-dihydroxypropyl)-5,6,7,8-tetrahydoro-4(1H)-pteridinone | ChEBI | BH4 | ChEBI | (1R,2S)-(2-amino-3,4,5,6,7,8-hexahydro-4-oxo-6-Pteridinyl)-1,2-propandiol | HMDB | 2-amino-6-(1,2-Dihydroxypropyl)-5,6,7,8-tetrahydoro-4(1H)-5,6,7,8-tetrahydro-2-amino-6-(1,2-dihydroxypropyl)-4(1H)-pteridinone | HMDB | 2-amino-6-(1,2-Dihydroxypropyl)-5,6,7,8-tetrahydro-4(1H)-pteridinone | HMDB | 5,6,7,8-erythro-Tetrahydrobiopterin | HMDB | 5,6,7,8-Tetra-H-biopterin | HMDB | 5,6,7,8-tetrahydro-2-amino-6-(1,2-Dihydroxypropyl)-4(1H)-pteridinone | HMDB | 5,6,7,8-Tetrahydrobiopterin | HMDB | L-erythro-2-amino-6-(1,2-Dihydroxypropyl)-5,6,7,8-tetrahydro-4(3H)-pteridinon | HMDB | Tetra-H-biopterin | HMDB | Tetra-hydro-biopterin | HMDB | 5,6,7,8-Tetrahydrodictyopterin | MeSH, HMDB | 6R-BH4 | MeSH, HMDB | 6R-L-erythro-5,6,7,8-Tetrahydrobiopterin | MeSH, HMDB | THBP | MeSH, HMDB | 5,6,7,8-Tetrahydrobiopterin, (S-(r*,s*))-isomer | MeSH, HMDB | BPH4 | MeSH, HMDB | D-threo-Tetrahydrobiopterin | MeSH, HMDB | 5,6,7,8-tetrahydro-L-Erythrobiopterin | MeSH, HMDB | Sapropterin dihydrochloride | MeSH, HMDB | tetrahydro-6-Biopterin | MeSH, HMDB | Kuvan | MeSH, HMDB | Phenylalanine hydroxylase cofactor | MeSH, HMDB | Sapropterin | MeSH, HMDB | 1-Butanone, 1-(2,4,5-trihydroxyphenyl) | MeSH, HMDB | 2,4,5-Trihydroxybutyrophenone | MeSH, HMDB | Trihydroxybutyrophenone | MeSH, HMDB | 2',4',5'-Trihydroxybutyrophenone | MeSH, HMDB |
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Chemical Formula | C9H15N5O3 |
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Average Molecular Mass | 241.247 g/mol |
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Monoisotopic Mass | 241.117 g/mol |
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CAS Registry Number | 17528-72-2 |
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IUPAC Name | 2-amino-6-(1,2-dihydroxypropyl)-1,4,5,6,7,8-hexahydropteridin-4-one |
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Traditional Name | tetrahydrobiopterin |
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SMILES | CC(O)C(O)C1CNC2=C(N1)C(=O)N=C(N)N2 |
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InChI Identifier | InChI=1S/C9H15N5O3/c1-3(15)6(16)4-2-11-7-5(12-4)8(17)14-9(10)13-7/h3-4,6,12,15-16H,2H2,1H3,(H4,10,11,13,14,17) |
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InChI Key | FNKQXYHWGSIFBK-UHFFFAOYSA-N |
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Chemical Taxonomy |
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Description | belongs to the class of organic compounds known as biopterins and derivatives. These are coenzymes containing a 2-amino-pteridine-4-one derivative. They are mainly synthesized in several parts of the body, including the pineal gland. |
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Kingdom | Organic compounds |
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Super Class | Organoheterocyclic compounds |
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Class | Pteridines and derivatives |
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Sub Class | Pterins and derivatives |
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Direct Parent | Biopterins and derivatives |
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Alternative Parents | |
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Substituents | - Biopterin
- Aminopyrimidine
- Pyrimidone
- Secondary aliphatic/aromatic amine
- Pyrimidine
- 1,3-aminoalcohol
- Vinylogous amide
- Heteroaromatic compound
- Secondary alcohol
- 1,2-diol
- 1,2-aminoalcohol
- Secondary amine
- Azacycle
- Hydrocarbon derivative
- Organic oxide
- Organopnictogen compound
- Primary amine
- Organooxygen compound
- Organonitrogen compound
- Organic oxygen compound
- Organic nitrogen compound
- Amine
- Alcohol
- Aromatic heteropolycyclic compound
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Molecular Framework | Aromatic heteropolycyclic compounds |
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External Descriptors | |
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Biological Properties |
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Status | Detected and Not Quantified |
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Origin | Not Available |
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Cellular Locations | Not Available |
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Biofluid Locations | Not Available |
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Tissue Locations | Not Available |
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Pathways | Not Available |
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Applications | Not Available |
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Biological Roles | Not Available |
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Chemical Roles | Not Available |
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Physical Properties |
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State | Not Available |
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Appearance | Not Available |
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Experimental Properties | Property | Value |
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Melting Point | Not Available | Boiling Point | Not Available | Solubility | Not Available |
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Predicted Properties | |
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Spectra |
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Spectra | Spectrum Type | Description | Splash Key | View |
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Predicted GC-MS | Predicted GC-MS Spectrum - GC-MS (Non-derivatized) - 70eV, Positive | splash10-014i-5900000000-804847492ab49a9a85fc | Spectrum | Predicted GC-MS | Predicted GC-MS Spectrum - GC-MS (2 TMS) - 70eV, Positive | splash10-000i-8095000000-47f102cc1afbed04012f | Spectrum | Predicted GC-MS | Predicted GC-MS Spectrum - GC-MS (Non-derivatized) - 70eV, Positive | Not Available | Spectrum | Predicted GC-MS | Predicted GC-MS Spectrum - GC-MS (Non-derivatized) - 70eV, Positive | Not Available | Spectrum | Predicted GC-MS | Predicted GC-MS Spectrum - GC-MS (TMS_2_7) - 70eV, Positive | Not Available | Spectrum | Predicted GC-MS | Predicted GC-MS Spectrum - GC-MS (TMS_2_8) - 70eV, Positive | Not Available | Spectrum | Predicted GC-MS | Predicted GC-MS Spectrum - GC-MS (TMS_2_10) - 70eV, Positive | Not Available | Spectrum | Predicted GC-MS | Predicted GC-MS Spectrum - GC-MS (TMS_2_12) - 70eV, Positive | Not Available | Spectrum | Predicted GC-MS | Predicted GC-MS Spectrum - GC-MS (TMS_2_14) - 70eV, Positive | Not Available | Spectrum | Predicted GC-MS | Predicted GC-MS Spectrum - GC-MS (TMS_2_16) - 70eV, Positive | Not Available | Spectrum | Predicted GC-MS | Predicted GC-MS Spectrum - GC-MS (TBDMS_1_2) - 70eV, Positive | Not Available | Spectrum | Predicted GC-MS | Predicted GC-MS Spectrum - GC-MS (TBDMS_1_3) - 70eV, Positive | Not Available | Spectrum | Predicted GC-MS | Predicted GC-MS Spectrum - GC-MS (TBDMS_1_5) - 70eV, Positive | Not Available | Spectrum | Predicted GC-MS | Predicted GC-MS Spectrum - GC-MS (TBDMS_1_6) - 70eV, Positive | Not Available | Spectrum | Predicted GC-MS | Predicted GC-MS Spectrum - GC-MS (TBDMS_2_1) - 70eV, Positive | Not Available | Spectrum | Predicted GC-MS | Predicted GC-MS Spectrum - GC-MS (TBDMS_2_2) - 70eV, Positive | Not Available | Spectrum | Predicted GC-MS | Predicted GC-MS Spectrum - GC-MS (TBDMS_2_3) - 70eV, Positive | Not Available | Spectrum | Predicted GC-MS | Predicted GC-MS Spectrum - GC-MS (TBDMS_2_6) - 70eV, Positive | Not Available | Spectrum | Predicted GC-MS | Predicted GC-MS Spectrum - GC-MS (TBDMS_2_7) - 70eV, Positive | Not Available | Spectrum | Predicted GC-MS | Predicted GC-MS Spectrum - GC-MS (TBDMS_2_8) - 70eV, Positive | Not Available | Spectrum | Predicted GC-MS | Predicted GC-MS Spectrum - GC-MS (TBDMS_2_9) - 70eV, Positive | Not Available | Spectrum | Predicted GC-MS | Predicted GC-MS Spectrum - GC-MS (TBDMS_2_11) - 70eV, Positive | Not Available | Spectrum | Predicted GC-MS | Predicted GC-MS Spectrum - GC-MS (TBDMS_2_12) - 70eV, Positive | Not Available | Spectrum | Predicted GC-MS | Predicted GC-MS Spectrum - GC-MS (TBDMS_2_15) - 70eV, Positive | Not Available | Spectrum | Predicted GC-MS | Predicted GC-MS Spectrum - GC-MS (TBDMS_2_16) - 70eV, Positive | Not Available | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 10V, Positive | splash10-006x-0090000000-241111b39335d9a7d02d | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 20V, Positive | splash10-01bl-0980000000-a6b56555596f17eb9943 | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 40V, Positive | splash10-01dj-1900000000-337483f746fd21c54572 | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 10V, Negative | splash10-0006-0290000000-5db8572d378da978b669 | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 20V, Negative | splash10-0007-0930000000-4e48e429709976699df9 | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 40V, Negative | splash10-0006-9600000000-8474626666ad84477dd8 | Spectrum |
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Toxicity Profile |
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Route of Exposure | Not Available |
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Mechanism of Toxicity | Not Available |
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Metabolism | Not Available |
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Toxicity Values | Not Available |
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Lethal Dose | Not Available |
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Carcinogenicity (IARC Classification) | Not Available |
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Uses/Sources | Not Available |
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Minimum Risk Level | Not Available |
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Health Effects | Not Available |
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Symptoms | Not Available |
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Treatment | Not Available |
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Concentrations |
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| Not Available |
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External Links |
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DrugBank ID | Not Available |
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HMDB ID | HMDB0258898 |
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FooDB ID | FDB021880 |
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Phenol Explorer ID | Not Available |
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KNApSAcK ID | C00018229 |
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BiGG ID | Not Available |
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BioCyc ID | Not Available |
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METLIN ID | Not Available |
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PDB ID | Not Available |
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Wikipedia Link | Tetrahydrobiopterin |
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Chemspider ID | 1093 |
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ChEBI ID | 15372 |
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PubChem Compound ID | Not Available |
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Kegg Compound ID | Not Available |
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YMDB ID | Not Available |
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ECMDB ID | ECMDB00027 |
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References |
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Synthesis Reference | Not Available |
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MSDS | Not Available |
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General References | Not Available |
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