Porson (CHEM024835)

IdentificationTaxonomyBiological PropertiesPhysical PropertiesToxicity ProfileSpectraConcentrationsLinksReferencesXML
Record Information
Version1.0
Creation Date2016-05-25 21:57:27 UTC
Update Date2016-11-09 01:17:58 UTC
Accession NumberCHEM024835
Identification
Common NamePorson
ClassSmall Molecule
DescriptionConstituent of Myrica gale (bog myrtle) Gibbon's verdict on the book, that it was "the most acute and accurate piece of criticism since the days of Bentley," may be considered as somewhat partial, as it was in defence of him that Porson had entered the field against Travis. But in the masterly sketch of Gibbon's work and style in the preface Porson does not write in a merely flattering tone. It is to be wished that on such a subject the tone of levity had been modified. But Porson says in his preface that he could treat the subject in no other manner, if he treated it at all: "To peruse such a mass of falsehood and sophistry and to write remarks upon it, without sometimes giving way to laughter and sometimes to indignation, was, to me at least, impossible." Travis has no mercy shown him, but he certainly deserved none. One is equally struck with the thorough grasp Porson displays of his subject, the amount of his miscellaneous learning, and the humour that pervades the whole. But it was then the unpopular side: the publisher is said to have lost money by the book; and one of his early friends, Mrs Turner of Norwich, cut down a legacy she had left Porson to £30 on being told that he had written what was described to her as a book against Christianity.; His library was divided into two parts, one of which was sold by auction; the other, containing the transcript of the Gale Photius, his books with his notes, and some letters from foreign scholars, was bought by Trinity College for 1000 guineas. His notebooks were found to contain, in the words of Bishop Blomfield, "a rich treasure of criticism in every branch of classical literature?everything carefully and correctly written and sometimes rewritten?quite fit to meet the public eye, without any diminution or addition." They have been carefully rearranged, and illustrate among other things his extraordinary penmanship and power of minute and accurate writing. Much remains unpublished. J. H. Monk, his successor as Greek professor, and C. J. Blomfield (both afterwards bishops) edited the Adversaria, consisting of the notes on Athenaeus and the Greek poets, and his prelection on Euripides; PP Dobree, afterwards Greek professor, the notes on Aristophanes and the lexicon of Photius. Besides these, from other sources, Professor T Gaisford edited his notes on Pausanias and Suidas, and Mr Kidd collected his scattered reviews. And, when Bishop Burgess attacked his literary character on the score of his Letters to Travis, Professor Turton (afterwards Bishop of Ely) came forward with a vindication.; In 1792 his fellowship was no longer tenable by a layman; and, rather than undertake duties for which he felt himself unfit, and which involved subscription to the Articles (though he had no difficulty as to signing a statement as to his conformity with the liturgy of the Church of England when elected Greek professor), he determined not to take holy orders, which would have enabled him to remain a fellow, and thus deprived himself of his only means of subsistence. He might have been retained in the society by being appointed to a lay fellowship, one of the two permanent lay fellowships which the statutes then permitted falling vacant just in time. It is said that this had been promised him, and it was certainly the custom in the college always to appoint the senior among the existing laymen, who otherwise would vacate his fellowship. But the master (Dr Postlethwaite), who had the nomination, used his privilege to nominate a younger man (John Heys), a nephew of his own, and thus Porson was turned adrift without any means of support. A subscription was, however, got up among his friends to provide an annuity to keep him from actual want; Cracherode, Cleaver Banks, Burney and Parr took the lead, and enough was collected to produce about £100 a year. He accepted it only on the condition that he should receive the interest during his lifetime, and that the principal, placed in the hands of trustees, should be returned to the donors at his death. When this occurred they or their survivors refused to receive the money, and it was with part of this sum that, in 1816, the Porson prize was founded to perpetuate his name at Cambridge. The remainder was devoted to the foundation of the Porson scholarship in the same university. This scholarship was first awarded in 1855. Porson is found in herbs and spices.
Contaminant Sources
  • FooDB Chemicals
Contaminant TypeNot Available
Chemical Structure
Thumb
MOLSDF3D-SDFPDBSMILESInChI View 3D Structure
SynonymsNot Available
Chemical FormulaC22H26O6
Average Molecular Mass386.438 g/mol
Monoisotopic Mass386.173 g/mol
CAS Registry Number56222-03-8
IUPAC Name8,15-dihydroxy-3,16,17-trimethoxytricyclo[12.3.1.1²,⁶]nonadeca-1(17),2,4,6(19),14(18),15-hexaen-9-one
Traditional Name8,15-dihydroxy-3,16,17-trimethoxytricyclo[12.3.1.1²,⁶]nonadeca-1(17),2,4,6(19),14(18),15-hexaen-9-one
SMILESCOC1=C2C=C(CC(O)C(=O)CCCCC3=CC2=C(OC)C(OC)=C3O)C=C1
InChI IdentifierInChI=1S/C22H26O6/c1-26-19-9-8-13-10-15(19)16-12-14(20(25)22(28-3)21(16)27-2)6-4-5-7-17(23)18(24)11-13/h8-10,12,18,24-25H,4-7,11H2,1-3H3
InChI KeyVHBRVHUPCPJJMZ-UHFFFAOYSA-N
Chemical Taxonomy
Description belongs to the class of organic compounds known as meta,meta-bridged biphenyls. These are cyclic diarylheptanoids where the two aryl groups are linked to each other by an ether group conjugated to their 3-position.
KingdomOrganic compounds
Super ClassPhenylpropanoids and polyketides
ClassDiarylheptanoids
Sub ClassCyclic diarylheptanoids
Direct ParentMeta,meta-bridged biphenyls
Alternative Parents
Substituents
  • Meta,meta-bridged biphenyl
  • Anisole
  • Alkyl aryl ether
  • Benzenoid
  • Cyclic ketone
  • Secondary alcohol
  • Ketone
  • Ether
  • Organic oxygen compound
  • Organic oxide
  • Hydrocarbon derivative
  • Organooxygen compound
  • Carbonyl group
  • Alcohol
  • Aromatic homopolycyclic compound
Molecular FrameworkAromatic homopolycyclic compounds
External DescriptorsNot Available
Biological Properties
StatusDetected and Not Quantified
OriginNot Available
Cellular LocationsNot Available
Biofluid LocationsNot Available
Tissue LocationsNot Available
PathwaysNot Available
ApplicationsNot Available
Biological RolesNot Available
Chemical RolesNot Available
Physical Properties
StateNot Available
AppearanceNot Available
Experimental Properties
PropertyValue
Melting PointNot Available
Boiling PointNot Available
SolubilityNot Available
Predicted Properties
PropertyValueSource
Water Solubility0.015 g/LALOGPS
logP3.33ALOGPS
logP3.58ChemAxon
logS-4.4ALOGPS
pKa (Strongest Acidic)10.17ChemAxon
pKa (Strongest Basic)-3.5ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count6ChemAxon
Hydrogen Donor Count2ChemAxon
Polar Surface Area85.22 ŲChemAxon
Rotatable Bond Count3ChemAxon
Refractivity105.98 m³·mol⁻¹ChemAxon
Polarizability40.91 ųChemAxon
Number of Rings3ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleNoChemAxon
Spectra
Spectra
Spectrum TypeDescriptionSplash KeyView
Predicted GC-MSPredicted GC-MS Spectrum - GC-MS (Non-derivatized) - 70eV, Positivesplash10-0avi-0009000000-fff2fbc9cf93fda14c15Spectrum
Predicted GC-MSPredicted GC-MS Spectrum - GC-MS (2 TMS) - 70eV, Positivesplash10-01bi-2000950000-b7d5f3c8222074f95e6dSpectrum
Predicted GC-MSPredicted GC-MS Spectrum - GC-MS (Non-derivatized) - 70eV, PositiveNot AvailableSpectrum
Predicted GC-MSPredicted GC-MS Spectrum - GC-MS (Non-derivatized) - 70eV, PositiveNot AvailableSpectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 10V, Positivesplash10-000i-0009000000-b59f79f1d0b471bd0134Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 20V, Positivesplash10-05n0-1009000000-aaee257253d9379a1f30Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 40V, Positivesplash10-0aou-4039000000-5e68ff81d2a6c71a7087Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 10V, Negativesplash10-000i-0009000000-620dbb7953b11e7aabfcSpectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 20V, Negativesplash10-000i-0009000000-6c786646d00bdfe6ff27Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 40V, Negativesplash10-029j-2069000000-5483085d6cc786aad5cdSpectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 10V, Negativesplash10-000i-0009000000-37da37047cdf1c71272eSpectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 20V, Negativesplash10-000i-0009000000-24382024cd96ba599b5fSpectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 40V, Negativesplash10-0h2r-0029000000-8640ef752f9415d9ab37Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 10V, Positivesplash10-00kr-0009000000-fa6db55a8454ab2d4923Spectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 20V, Positivesplash10-0fri-0009000000-2014d1516dfad159036dSpectrum
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 40V, Positivesplash10-0udi-0059000000-d4cdb7a8da9b4d44e44bSpectrum
Toxicity Profile
Route of ExposureNot Available
Mechanism of ToxicityNot Available
MetabolismNot Available
Toxicity ValuesNot Available
Lethal DoseNot Available
Carcinogenicity (IARC Classification)Not Available
Uses/SourcesNot Available
Minimum Risk LevelNot Available
Health EffectsNot Available
SymptomsNot Available
TreatmentNot Available
Concentrations
Not Available
DrugBank IDNot Available
HMDB IDHMDB0030810
FooDB IDFDB002764
Phenol Explorer IDNot Available
KNApSAcK IDNot Available
BiGG IDNot Available
BioCyc IDNot Available
METLIN IDNot Available
PDB IDNot Available
Wikipedia LinkRichard Porson
Chemspider IDNot Available
ChEBI IDNot Available
PubChem Compound ID131751083
Kegg Compound IDNot Available
YMDB IDNot Available
ECMDB IDNot Available
References
Synthesis ReferenceNot Available
MSDSNot Available
General References
1. Yannai, Shmuel. (2004) Dictionary of food compounds with CD-ROM: Additives, flavors, and ingredients. Boca Raton: Chapman & Hall/CRC.