ContaminantDB: L-Pipecolic acid

Identification Taxonomy Biological Properties Physical Properties Toxicity Profile Spectra Concentrations Links References XML

Record Information

Version

1.0

Creation Date

2016-05-25 18:53:53 UTC

Update Date

2016-11-09 01:17:35 UTC

Accession Number

CHEM022801

Identification

Common Name

L-Pipecolic acid

Class

Small Molecule

Description

The L-enantiomer of pipecolic acid. It is a metabolite of lysine.

Contaminant Sources

FooDB Chemicals
HMDB Contaminants - Feces

Contaminant Type

Not Available

Chemical Structure

MOL SDF PDB SMILES InChI

Synonyms

Value	Source
(S)-(-)-Pipecolic acid	ChEBI
(S)-Pipecolic acid	ChEBI
(S)-Piperidine-2-carboxylic acid	ChEBI
2-Piperidinecarboxylic acid	ChEBI
L-(-)-Pipecolic acid	ChEBI
Pipecolic acid	ChEBI
Pipecolinic acid	ChEBI
(S)-(-)-Pipecolate	Generator
(S)-Pipecolate	Generator
(S)-Piperidine-2-carboxylate	Generator
2-Piperidinecarboxylate	Generator
L-(-)-Pipecolate	Generator
Pipecolate	Generator
Pipecolinate	Generator
L-Pipecolate	Generator
(-)-Pipecolate	HMDB
(-)-Pipecolic acid	HMDB
(S)-(-)-2-Piperidinecarboxylate	HMDB
(S)-(-)-2-Piperidinecarboxylic acid	HMDB
(S)-2-Piperidinecarboxylate	HMDB
(S)-2-Piperidinecarboxylic acid	HMDB
(S)-Pipecolinate	HMDB
(S)-Pipecolinic acid	HMDB
L-Homoproline	HMDB
L-Pipecolinate	HMDB
L-Pipecolinic acid	HMDB
L-Piperidine-2-carboxylate	HMDB
L-Piperidine-2-carboxylic acid	HMDB
Pipecolic acid, (+,-)-isomer	HMDB
Pipecolic acid, 14C-labeled CPD, (+,-)-isomer	HMDB
Homopipecolic acid	HMDB
Pipecolic acid, ion(1-), (+,-)-isomer	HMDB
Pipecolic acid, ion(1-), (S)-isomer	HMDB
Pipecolic acid hydrochloride, (+-)-isomer	HMDB
Pipecolic acid, (S)-isomer	HMDB
Pipecolic acid, (R)-isomer	HMDB
Pipecolic acid, ion (1-)	HMDB
Pipecolic acid, monopotassium salt	HMDB
(2S)-2-Piperidinecarboxylic acid	HMDB
(-)-Pipecolinic acid	HMDB
(2S)-Piperidine-2-carboxylic acid	HMDB
(RS)-2-Piperidinecarboxylic acid	HMDB
(±)-2-piperidinecarboxylic acid	HMDB
(±)-pipecolic acid	HMDB
(±)-pipecolinic acid	HMDB
2-Carboxypiperidine	HMDB
2-Pipecolinic acid	HMDB
2-Piperidinylcarboxylic acid	HMDB
DL-2-Piperidinecarboxylic acid	HMDB
DL-Pipecolic acid	HMDB
DL-Pipecolinic acid	HMDB
Dihydrobaikiane	HMDB
Hexahydro-2-picolinic acid	HMDB
Homoproline	HMDB
Piperidine-6-carboxylic acid	HMDB
Piperolinic acid	HMDB
alpha-Pipecolinic acid	HMDB
Α-pipecolinic acid	HMDB
L-Pipecolic acid	PhytoBank

Chemical Formula

C₆H₁₁NO₂

Average Molecular Mass

129.157 g/mol

Monoisotopic Mass

129.079 g/mol

CAS Registry Number

3105-95-1

IUPAC Name

(2S)-piperidine-2-carboxylic acid

Traditional Name

L-pipecolic acid

SMILES

OC(=O)[C@@H]1CCCCN1

InChI Identifier

InChI=1S/C6H11NO2/c8-6(9)5-3-1-2-4-7-5/h5,7H,1-4H2,(H,8,9)/t5-/m0/s1

InChI Key

HXEACLLIILLPRG-YFKPBYRVSA-N

Chemical Taxonomy

Description

belongs to the class of organic compounds known as l-alpha-amino acids. These are alpha amino acids which have the L-configuration of the alpha-carbon atom.

Kingdom

Organic compounds

Super Class

Organic acids and derivatives

Class

Carboxylic acids and derivatives

Sub Class

Amino acids, peptides, and analogues

Direct Parent

L-alpha-amino acids

Alternative Parents

Substituents

L-alpha-amino acid
Piperidinecarboxylic acid
Piperidine
Amino acid
Carboxylic acid
Secondary aliphatic amine
Monocarboxylic acid or derivatives
Secondary amine
Organoheterocyclic compound
Azacycle
Organic oxygen compound
Organic nitrogen compound
Organooxygen compound
Organonitrogen compound
Amine
Carbonyl group
Organopnictogen compound
Hydrocarbon derivative
Organic oxide
Aliphatic heteromonocyclic compound

Molecular Framework

Aliphatic heteromonocyclic compounds

External Descriptors

pipecolic acid (CHEBI:30913 )
Piperidine alkaloids (C00408 )

Biological Properties

Status

Detected and Not Quantified

Origin

Not Available

Cellular Locations

Not Available

Biofluid Locations

Not Available

Tissue Locations

Not Available

Pathways

Not Available

Applications

Not Available

Biological Roles

Not Available

Chemical Roles

Not Available

Physical Properties

State

Not Available

Appearance

Not Available

Experimental Properties

Property	Value
Melting Point	Not Available
Boiling Point	Not Available
Solubility	Not Available

Predicted Properties

Property	Value	Source
Water Solubility	158 g/L	ALOGPS
logP	-2.2	ALOGPS
logP	-2.1	ChemAxon
logS	0.09	ALOGPS
pKa (Strongest Acidic)	2.06	ChemAxon
pKa (Strongest Basic)	10.39	ChemAxon
Physiological Charge	0	ChemAxon
Hydrogen Acceptor Count	3	ChemAxon
Hydrogen Donor Count	2	ChemAxon
Polar Surface Area	49.33 Å²	ChemAxon
Rotatable Bond Count	1	ChemAxon
Refractivity	32.67 m³·mol⁻¹	ChemAxon
Polarizability	13.49 Å³	ChemAxon
Number of Rings	1	ChemAxon
Bioavailability	1	ChemAxon
Rule of Five	Yes	ChemAxon
Ghose Filter	No	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	No	ChemAxon

Spectra

Spectrum Type	Description	Splash Key	View
GC-MS	GC-MS Spectrum - GC-EI-TOF (Pegasus III TOF-MS system, Leco; GC 6890, Agilent Technologies) (Non-derivatized)	splash10-0a4i-0900000000-c7875e682dfb275cdf1e	Spectrum
GC-MS	GC-MS Spectrum - GC-MS (1 TMS)	splash10-001i-9100000000-07741b1b7d650447197e	Spectrum
GC-MS	GC-MS Spectrum - GC-MS (2 TMS)	splash10-0a4i-1900000000-1b1313072749567d8a9e	Spectrum
GC-MS	GC-MS Spectrum - GC-MS (1 MEOX; 2 TMS)	splash10-0pb9-3960000000-8e89c177d71b5faabdb2	Spectrum
GC-MS	GC-MS Spectrum - GC-EI-TOF (Non-derivatized)	splash10-0a4i-0900000000-c7875e682dfb275cdf1e	Spectrum
GC-MS	GC-MS Spectrum - GC-MS (Non-derivatized)	splash10-0a4i-1900000000-1b1313072749567d8a9e	Spectrum
GC-MS	GC-MS Spectrum - GC-MS (Non-derivatized)	splash10-0pb9-3960000000-8e89c177d71b5faabdb2	Spectrum
GC-MS	GC-MS Spectrum - GC-MS (Non-derivatized)	splash10-001i-9100000000-07741b1b7d650447197e	Spectrum
Predicted GC-MS	Predicted GC-MS Spectrum - GC-MS (Non-derivatized) - 70eV, Positive	splash10-001i-9100000000-335cf7f41fca5cbc84cf	Spectrum
Predicted GC-MS	Predicted GC-MS Spectrum - GC-MS (1 TMS) - 70eV, Positive	splash10-05fu-9700000000-8003521353d4d37af49f	Spectrum
Predicted GC-MS	Predicted GC-MS Spectrum - GC-MS (Non-derivatized) - 70eV, Positive	Not Available	Spectrum
Predicted GC-MS	Predicted GC-MS Spectrum - GC-MS (TMS_1_2) - 70eV, Positive	Not Available	Spectrum
Predicted GC-MS	Predicted GC-MS Spectrum - GC-MS (TBDMS_1_1) - 70eV, Positive	Not Available	Spectrum
Predicted GC-MS	Predicted GC-MS Spectrum - GC-MS (TBDMS_1_2) - 70eV, Positive	Not Available	Spectrum
LC-MS/MS	LC-MS/MS Spectrum - Quattro_QQQ 10V, N/A (Annotated)	splash10-001i-8900000000-b67eb6eabd8fb1b2824a	Spectrum
LC-MS/MS	LC-MS/MS Spectrum - Quattro_QQQ 25V, N/A (Annotated)	splash10-001i-9000000000-b01a5574139ce1222c4d	Spectrum
LC-MS/MS	LC-MS/MS Spectrum - Quattro_QQQ 40V, N/A (Annotated)	splash10-0a4i-9000000000-d80733b289711920626b	Spectrum
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 10V, Negative	splash10-004i-0900000000-6d82525e15d98dd794db	Spectrum
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 20V, Negative	splash10-004i-0900000000-abb8b4f2daaa91bfa758	Spectrum
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 30V, Negative	splash10-004i-1900000000-b668d1df137fa1685b6d	Spectrum
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 40V, Negative	splash10-0002-9000000000-5ec763c9c55715bd01df	Spectrum
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 50V, Negative	splash10-0002-9000000000-5a62167bd787768808f7	Spectrum
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 10V, Positive	splash10-001i-0900000000-edd41fa2c224ec5f5a1e	Spectrum
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 20V, Positive	splash10-001i-9100000000-7ed3d7197cd0f23403b6	Spectrum
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 30V, Positive	splash10-001i-9000000000-e5b2220b7410a3429b95	Spectrum
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 40V, Positive	splash10-001i-9000000000-baf8dab4263881ac49ea	Spectrum
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 50V, Positive	splash10-0a59-9000000000-d1dc7829582bfd61d47b	Spectrum
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-QQ , negative	splash10-004i-0900000000-6d82525e15d98dd794db	Spectrum
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-QQ , negative	splash10-004i-0900000000-abb8b4f2daaa91bfa758	Spectrum
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-QQ , negative	splash10-004i-1900000000-b668d1df137fa1685b6d	Spectrum
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-QQ , negative	splash10-0002-9000000000-5ec763c9c55715bd01df	Spectrum
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-QQ , negative	splash10-0002-9000000000-5a62167bd787768808f7	Spectrum
LC-MS/MS	LC-MS/MS Spectrum - LC-ESI-QQ , positive	splash10-001i-0900000000-edd41fa2c224ec5f5a1e	Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 10V, Positive	splash10-001i-3900000000-bf71d20a7c8e71d335e5	Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 20V, Positive	splash10-001i-9400000000-fa70645b026293d659de	Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 40V, Positive	splash10-053u-9000000000-f849cc3c4b11bc7d4de7	Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 10V, Negative	splash10-004i-2900000000-bf800b5cd197887a11d5	Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 20V, Negative	splash10-003r-7900000000-8a0e9f51df4006740863	Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - 40V, Negative	splash10-001i-9000000000-effc196b5c15971f985a	Spectrum
1D NMR	1H NMR Spectrum	Not Available	Spectrum
1D NMR	1H NMR Spectrum	Not Available	Spectrum
1D NMR	13C NMR Spectrum	Not Available	Spectrum
1D NMR	1H NMR Spectrum	Not Available	Spectrum
1D NMR	13C NMR Spectrum	Not Available	Spectrum
1D NMR	1H NMR Spectrum	Not Available	Spectrum
1D NMR	13C NMR Spectrum	Not Available	Spectrum
1D NMR	1H NMR Spectrum	Not Available	Spectrum
1D NMR	13C NMR Spectrum	Not Available	Spectrum
1D NMR	1H NMR Spectrum	Not Available	Spectrum
1D NMR	13C NMR Spectrum	Not Available	Spectrum
1D NMR	1H NMR Spectrum	Not Available	Spectrum
1D NMR	13C NMR Spectrum	Not Available	Spectrum
1D NMR	1H NMR Spectrum	Not Available	Spectrum
1D NMR	13C NMR Spectrum	Not Available	Spectrum
1D NMR	1H NMR Spectrum	Not Available	Spectrum
1D NMR	13C NMR Spectrum	Not Available	Spectrum
1D NMR	1H NMR Spectrum	Not Available	Spectrum
1D NMR	13C NMR Spectrum	Not Available	Spectrum
1D NMR	1H NMR Spectrum	Not Available	Spectrum
1D NMR	13C NMR Spectrum	Not Available	Spectrum
2D NMR	[1H,13C] 2D NMR Spectrum	Not Available	Spectrum