Record Information |
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Version | 1.0 |
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Creation Date | 2016-05-25 18:22:31 UTC |
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Update Date | 2016-11-09 01:17:26 UTC |
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Accession Number | CHEM022168 |
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Identification |
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Common Name | Homatropine Methylbromide |
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Class | Small Molecule |
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Description | Homatropine methylbromide is a quaternary ammonium muscarinic acetylcholine receptor antagonist belonging to the group of medicines called anti-muscarinics. Homatropine is used to treat duodenal or stomach ulcers or intestine problems. It can be used together with antacids or other medicine in the treatment of peptic ulcer. It may also be used to prevent nausea, vomiting, and motion sickness. |
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Contaminant Sources | - HMDB Contaminants - Urine
- STOFF IDENT Compounds
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Contaminant Type | Not Available |
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Chemical Structure | |
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Synonyms | Value | Source |
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3-alpha-Hydroxy-8-methyl-1-alpha-H,5-alpha-H-tropanium bromide mandelate | ChEBI | 8-Methylhomatropinium bromide | ChEBI | Homatropini methylbromidum | ChEBI | Methylbromure d'homatropine | ChEBI | Methylhomatropine bromide | ChEBI | Methylhomatropinum bromatum | ChEBI | Metilbromuro de homatropina | ChEBI | Omatropina metilbromuro | ChEBI | Tropinium methobromide mandelate | ChEBI | 3-a-Hydroxy-8-methyl-1-a-H,5-a-H-tropanium bromide mandelate | Generator | 3-a-Hydroxy-8-methyl-1-a-H,5-a-H-tropanium bromide mandelic acid | Generator | 3-alpha-Hydroxy-8-methyl-1-alpha-H,5-alpha-H-tropanium bromide mandelic acid | Generator | 3-Α-hydroxy-8-methyl-1-α-H,5-α-H-tropanium bromide mandelate | Generator | 3-Α-hydroxy-8-methyl-1-α-H,5-α-H-tropanium bromide mandelic acid | Generator | Tropinium methobromide mandelic acid | Generator | Homatropine methylbromide iodide, (3(S)-endo)-isomer | MeSH | Homatropine methylbromide, endo-(+-)-isomer | MeSH | HMBromide | MeSH | Homatropine methylbromide iodide, (3(R)-endo)-isomer | MeSH | Homatropine methylbromide, (3(R)-endo)-isomer | MeSH | Homatropine methylbromide, (3(S)-endo)-isomer | MeSH |
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Chemical Formula | C17H24BrNO3 |
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Average Molecular Mass | 370.281 g/mol |
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Monoisotopic Mass | 369.094 g/mol |
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CAS Registry Number | 80-49-9 |
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IUPAC Name | 3-[(2-hydroxy-2-phenylacetyl)oxy]-8,8-dimethyl-8-azabicyclo[3.2.1]octan-8-ium bromide |
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Traditional Name | 3-[(2-hydroxy-2-phenylacetyl)oxy]-8,8-dimethyl-8-azabicyclo[3.2.1]octan-8-ium bromide |
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SMILES | [Br-].C[N+]1(C)C2CCC1CC(C2)OC(=O)C(O)C1=CC=CC=C1 |
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InChI Identifier | InChI=1S/C17H24NO3.BrH/c1-18(2)13-8-9-14(18)11-15(10-13)21-17(20)16(19)12-6-4-3-5-7-12;/h3-7,13-16,19H,8-11H2,1-2H3;1H/q+1;/p-1 |
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InChI Key | FUFVKLQESJNNAN-UHFFFAOYSA-M |
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Chemical Taxonomy |
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Description | belongs to the class of organic compounds known as tropane alkaloids. These are organic compounds containing the nitrogenous bicyclic alkaloid parent N-Methyl-8-azabicyclo[3.2.1]octane. |
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Kingdom | Organic compounds |
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Super Class | Alkaloids and derivatives |
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Class | Tropane alkaloids |
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Sub Class | Not Available |
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Direct Parent | Tropane alkaloids |
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Alternative Parents | |
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Substituents | - Tropane alkaloid
- Monocyclic benzene moiety
- Piperidine
- N-alkylpyrrolidine
- Benzenoid
- Pyrrolidine
- Tetraalkylammonium salt
- Quaternary ammonium salt
- Carboxylic acid ester
- Secondary alcohol
- Carboxylic acid derivative
- Monocarboxylic acid or derivatives
- Azacycle
- Organoheterocyclic compound
- Organic bromide salt
- Hydrocarbon derivative
- Organic oxide
- Organopnictogen compound
- Organooxygen compound
- Organonitrogen compound
- Amine
- Organic oxygen compound
- Alcohol
- Carbonyl group
- Aromatic alcohol
- Organic nitrogen compound
- Organic zwitterion
- Organic salt
- Aromatic heteropolycyclic compound
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Molecular Framework | Aromatic heteropolycyclic compounds |
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External Descriptors | |
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Biological Properties |
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Status | Detected and Not Quantified |
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Origin | Not Available |
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Cellular Locations | Not Available |
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Biofluid Locations | Not Available |
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Tissue Locations | Not Available |
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Pathways | Not Available |
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Applications | Not Available |
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Biological Roles | Not Available |
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Chemical Roles | Not Available |
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Physical Properties |
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State | Not Available |
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Appearance | Not Available |
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Experimental Properties | Property | Value |
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Melting Point | Not Available | Boiling Point | Not Available | Solubility | Not Available |
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Predicted Properties | |
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Spectra |
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Spectra | Spectrum Type | Description | Splash Key | View |
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Predicted GC-MS | Predicted GC-MS Spectrum - GC-MS (Non-derivatized) - 70eV, Positive | splash10-0a4r-3900000000-340f2398d1807e9c012c | Spectrum | Predicted GC-MS | Predicted GC-MS Spectrum - GC-MS (1 TMS) - 70eV, Positive | splash10-004i-2900000000-a5b631062e363c2d6d39 | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 10V, Positive | splash10-0a4r-0921000000-7c5c213de8dd237d232d | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 20V, Positive | splash10-05nr-0940000000-1bb29c7fc382721ab56f | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 40V, Positive | splash10-01p9-2910000000-d05b654c79ca73be6bf7 | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 10V, Negative | splash10-001i-0985000000-bcba876c06149612baa8 | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 20V, Negative | splash10-001i-1490000000-8332eb1ac0c9eb7a44d2 | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 40V, Negative | splash10-0690-3790000000-fa0e2c9a309a506b0de1 | Spectrum |
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Toxicity Profile |
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Route of Exposure | Not Available |
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Mechanism of Toxicity | Not Available |
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Metabolism | Not Available |
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Toxicity Values | Not Available |
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Lethal Dose | Not Available |
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Carcinogenicity (IARC Classification) | Not Available |
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Uses/Sources | Not Available |
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Minimum Risk Level | Not Available |
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Health Effects | Not Available |
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Symptoms | Not Available |
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Treatment | Not Available |
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Concentrations |
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| Not Available |
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External Links |
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DrugBank ID | DB00725 |
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HMDB ID | HMDB0014863 |
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FooDB ID | Not Available |
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Phenol Explorer ID | Not Available |
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KNApSAcK ID | Not Available |
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BiGG ID | Not Available |
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BioCyc ID | Not Available |
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METLIN ID | Not Available |
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PDB ID | Not Available |
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Wikipedia Link | Homatropine methylbromide |
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Chemspider ID | Not Available |
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ChEBI ID | 50373 |
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PubChem Compound ID | 6646 |
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Kegg Compound ID | Not Available |
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YMDB ID | Not Available |
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ECMDB ID | Not Available |
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References |
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Synthesis Reference | Not Available |
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MSDS | Not Available |
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General References | Not Available |
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