Record Information |
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Version | 1.0 |
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Creation Date | 2016-05-22 07:18:19 UTC |
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Update Date | 2016-11-09 01:16:14 UTC |
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Accession Number | CHEM020658 |
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Identification |
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Common Name | Clevudine |
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Class | Small Molecule |
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Description | Not Available |
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Contaminant Sources | - ToxCast & Tox21 Chemicals
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Contaminant Type | Not Available |
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Chemical Structure | |
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Synonyms | Value | Source |
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1-(2-fluoro-2-Deoxy-beta-arabinofuranosyl)thymine | MeSH | 1-(2-fluoro-5-Methyl-beta,L-arabinofuranosyl)uracil | MeSH | 2'-Deoxy-2'-fluoroarabinofuranosylthymine | MeSH | 2'-fluoro-1-beta-Arabinofuranosyl-5-methyluracil | MeSH | 2'-fluoro-5-Methyl-1-beta-D-arabinofuranosyluracil | MeSH | 2'-fluoro-5-Methyl-1-beta-arabinosyluracil | MeSH | 2'-fluoro-5-Methylarabinosyluracil | MeSH | 2'-fluoro-5-Methylarabinosyluracil, 2-(14)C-labeled | MeSH | Clevudine | MeSH | FMAU | MeSH | L-FMAU | MeSH | D-FMAU | MeSH | 5-Methyl-2'-fluoroarauracil | MeSH | 1-(2-Fluoro-2-deoxy-beta-D-arabinofuranosyl)thymine | MeSH |
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Chemical Formula | C10H13FN2O5 |
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Average Molecular Mass | 260.221 g/mol |
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Monoisotopic Mass | 260.081 g/mol |
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CAS Registry Number | 163252-36-6 |
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IUPAC Name | 1-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-hydroxy-5-methyl-1,2-dihydropyrimidin-2-one |
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Traditional Name | 1-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-hydroxy-5-methylpyrimidin-2-one |
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SMILES | [H][C@]1(CO)O[C@@]([H])(N2C=C(C)C(O)=NC2=O)[C@@]([H])(F)[C@]1([H])O |
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InChI Identifier | InChI=1S/C10H13FN2O5/c1-4-2-13(10(17)12-8(4)16)9-6(11)7(15)5(3-14)18-9/h2,5-7,9,14-15H,3H2,1H3,(H,12,16,17)/t5-,6+,7-,9-/m1/s1 |
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InChI Key | GBBJCSTXCAQSSJ-JVZYCSMKSA-N |
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Chemical Taxonomy |
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Description | belongs to the class of organic compounds known as pyrimidine 2'-deoxyribonucleosides. Pyrimidine 2'-deoxyribonucleosides are compounds consisting of a pyrimidine linked to a ribose which lacks a hydroxyl group at position 2. |
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Kingdom | Organic compounds |
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Super Class | Nucleosides, nucleotides, and analogues |
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Class | Pyrimidine nucleosides |
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Sub Class | Pyrimidine 2'-deoxyribonucleosides |
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Direct Parent | Pyrimidine 2'-deoxyribonucleosides |
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Alternative Parents | |
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Substituents | - Pyrimidine 2'-deoxyribonucleoside
- Pyrimidone
- Hydropyrimidine
- Pyrimidine
- Tetrahydrofuran
- Heteroaromatic compound
- Vinylogous amide
- Fluorohydrin
- Halohydrin
- Lactam
- Secondary alcohol
- Urea
- Azacycle
- Organoheterocyclic compound
- Oxacycle
- Organic oxide
- Organic oxygen compound
- Primary alcohol
- Organooxygen compound
- Organonitrogen compound
- Organofluoride
- Organohalogen compound
- Alkyl halide
- Organic nitrogen compound
- Alkyl fluoride
- Hydrocarbon derivative
- Alcohol
- Organopnictogen compound
- Aromatic heteromonocyclic compound
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Molecular Framework | Aromatic heteromonocyclic compounds |
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External Descriptors | Not Available |
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Biological Properties |
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Status | Detected and Not Quantified |
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Origin | Not Available |
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Cellular Locations | Not Available |
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Biofluid Locations | Not Available |
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Tissue Locations | Not Available |
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Pathways | Not Available |
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Applications | Not Available |
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Biological Roles | Not Available |
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Chemical Roles | Not Available |
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Physical Properties |
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State | Not Available |
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Appearance | Not Available |
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Experimental Properties | Property | Value |
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Melting Point | Not Available | Boiling Point | Not Available | Solubility | Not Available |
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Predicted Properties | |
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Spectra |
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Spectra | Spectrum Type | Description | Splash Key | View |
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Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 10V, Positive | splash10-004i-0900000000-af3de878092804213b25 | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 20V, Positive | splash10-004i-5900000000-04fe37a71dcee53f7641 | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 40V, Positive | splash10-0a7j-9600000000-1439442a96b2db10e0a6 | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 10V, Negative | splash10-06vl-2490000000-3cbbd3571cad4ad5bb05 | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 20V, Negative | splash10-016r-3940000000-3b38afa22362d19cbe11 | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 40V, Negative | splash10-0006-9200000000-4c10d3c40755185b0460 | Spectrum |
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Toxicity Profile |
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Route of Exposure | Not Available |
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Mechanism of Toxicity | Not Available |
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Metabolism | Not Available |
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Toxicity Values | Not Available |
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Lethal Dose | Not Available |
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Carcinogenicity (IARC Classification) | Not Available |
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Uses/Sources | Not Available |
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Minimum Risk Level | Not Available |
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Health Effects | Not Available |
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Symptoms | Not Available |
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Treatment | Not Available |
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Concentrations |
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External Links |
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DrugBank ID | Not Available |
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HMDB ID | Not Available |
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FooDB ID | Not Available |
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Phenol Explorer ID | Not Available |
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KNApSAcK ID | Not Available |
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BiGG ID | Not Available |
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BioCyc ID | Not Available |
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METLIN ID | Not Available |
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PDB ID | Not Available |
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Wikipedia Link | Not Available |
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Chemspider ID | Not Available |
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ChEBI ID | Not Available |
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PubChem Compound ID | 72327 |
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Kegg Compound ID | Not Available |
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YMDB ID | Not Available |
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ECMDB ID | Not Available |
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References |
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Synthesis Reference | Not Available |
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MSDS | Not Available |
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General References | Not Available |
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