Record Information |
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Version | 1.0 |
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Creation Date | 2016-05-22 05:18:18 UTC |
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Update Date | 2016-11-09 01:15:49 UTC |
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Accession Number | CHEM018516 |
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Identification |
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Common Name | Tricirbine |
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Class | Small Molecule |
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Description | A nucleoside analogue in which the nucleobase portion is a 1,4,5,6,8-pentaazaacenaphthylene ring system substituted with an amino group at position 3, and a methyl group at position 5 and is bound to the beta-D-ribofuranosyl moiety by an N(1)-glycosidic linkage. |
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Contaminant Sources | - ToxCast & Tox21 Chemicals
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Contaminant Type | Not Available |
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Chemical Structure | |
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Synonyms | Value | Source |
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TCN | ChEBI | 6-ARPPP | MeSH | 3-amino-1,5-dihydro-5-Methyl-I-beta-D-ribofuranosyl-1,4,5,6,8- pentaazaacenaphthylene | MeSH | 6-amino-4-Methyl-8-(beta-D-ribofuranosyl)-(4H,8H)pyrrolo(4,3,2-de)pyrimido(4,5-c)pyridazine | MeSH |
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Chemical Formula | C13H16N6O4 |
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Average Molecular Mass | 320.309 g/mol |
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Monoisotopic Mass | 320.123 g/mol |
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CAS Registry Number | 35943-35-2 |
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IUPAC Name | (2R,3S,4R,5R)-2-(hydroxymethyl)-5-{5-imino-7-methyl-2,6,7,9,11-pentaazatricyclo[6.3.1.0⁴,¹²]dodeca-1(11),3,8(12),9-tetraen-2-yl}oxolane-3,4-diol |
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Traditional Name | (2R,3S,4R,5R)-2-(hydroxymethyl)-5-{5-imino-7-methyl-2,6,7,9,11-pentaazatricyclo[6.3.1.0⁴,¹²]dodeca-1(11),3,8(12),9-tetraen-2-yl}oxolane-3,4-diol |
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SMILES | [H][C@]1(CO)O[C@@]([H])(N2C=C3C4=C(N=CN=C24)N(C)NC3=N)[C@]([H])(O)[C@]1([H])O |
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InChI Identifier | InChI=1S/C13H16N6O4/c1-18-11-7-5(10(14)17-18)2-19(12(7)16-4-15-11)13-9(22)8(21)6(3-20)23-13/h2,4,6,8-9,13,20-22H,3H2,1H3,(H2,14,17)/t6-,8-,9-,13-/m1/s1 |
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InChI Key | HOGVTUZUJGHKPL-HTVVRFAVSA-N |
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Chemical Taxonomy |
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Description | belongs to the class of organic compounds known as glycosylamines. Glycosylamines are compounds consisting of an amine with a beta-N-glycosidic bond to a carbohydrate, thus forming a cyclic hemiaminal ether bond (alpha-amino ether). |
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Kingdom | Organic compounds |
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Super Class | Organic oxygen compounds |
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Class | Organooxygen compounds |
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Sub Class | Carbohydrates and carbohydrate conjugates |
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Direct Parent | Glycosylamines |
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Alternative Parents | |
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Substituents | - N-glycosyl compound
- Pentose monosaccharide
- Pyrrolo[2,3-d]pyrimidine
- Pyrrolo[3,4-d]pyridazine
- Pyrrolopyrimidine
- Monosaccharide
- Pyridazine
- Pyrimidine
- Imidolactam
- Substituted pyrrole
- Heteroaromatic compound
- Pyrrole
- Tetrahydrofuran
- Carboxylic acid amidrazone
- Secondary alcohol
- Azacycle
- Oxacycle
- Organoheterocyclic compound
- Primary alcohol
- Hydrocarbon derivative
- Organonitrogen compound
- Organopnictogen compound
- Organic nitrogen compound
- Alcohol
- Aromatic heteropolycyclic compound
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Molecular Framework | Aromatic heteropolycyclic compounds |
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External Descriptors | |
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Biological Properties |
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Status | Detected and Not Quantified |
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Origin | Not Available |
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Cellular Locations | Not Available |
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Biofluid Locations | Not Available |
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Tissue Locations | Not Available |
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Pathways | Not Available |
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Applications | Not Available |
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Biological Roles | Not Available |
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Chemical Roles | Not Available |
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Physical Properties |
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State | Not Available |
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Appearance | Not Available |
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Experimental Properties | Property | Value |
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Melting Point | Not Available | Boiling Point | Not Available | Solubility | Not Available |
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Predicted Properties | |
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Spectra |
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Spectra | Spectrum Type | Description | Splash Key | View |
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Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 10V, Positive | splash10-0079-0916000000-73dd86cbe2e15c326525 | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 20V, Positive | splash10-000i-1900000000-d53846d65c6152b02424 | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 40V, Positive | splash10-0079-1900000000-e553be1c9d0d3bb6310c | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 10V, Negative | splash10-014r-0529000000-c5134d63d7bc50a0dc30 | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 20V, Negative | splash10-000i-0910000000-bb38f9b89df6d2778644 | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 40V, Negative | splash10-00dr-0900000000-a0466d1a7c9fe1956cd0 | Spectrum |
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Toxicity Profile |
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Route of Exposure | Not Available |
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Mechanism of Toxicity | Not Available |
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Metabolism | Not Available |
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Toxicity Values | Not Available |
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Lethal Dose | Not Available |
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Carcinogenicity (IARC Classification) | Not Available |
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Uses/Sources | Not Available |
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Minimum Risk Level | Not Available |
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Health Effects | Not Available |
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Symptoms | Not Available |
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Treatment | Not Available |
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Concentrations |
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| Not Available |
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External Links |
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DrugBank ID | DB12405 |
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HMDB ID | Not Available |
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FooDB ID | Not Available |
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Phenol Explorer ID | Not Available |
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KNApSAcK ID | Not Available |
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BiGG ID | Not Available |
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BioCyc ID | Not Available |
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METLIN ID | Not Available |
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PDB ID | Not Available |
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Wikipedia Link | Triciribine |
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Chemspider ID | Not Available |
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ChEBI ID | 65310 |
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PubChem Compound ID | 65399 |
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Kegg Compound ID | Not Available |
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YMDB ID | Not Available |
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ECMDB ID | Not Available |
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References |
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Synthesis Reference | Not Available |
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MSDS | Not Available |
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General References | |
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