Identification Common Name Dorzolamide hydrochloride Class Small Molecule Description The hydrochloride salt of dorzolamide. It is used in ophthalmic solutions to lower increased intraocular pressure in the treatment of open-angle glaucoma and ocular hypertension. Contaminant Sources STOFF IDENT Compounds
ToxCast & Tox21 Chemicals Contaminant Type Not Available Chemical Structure Synonyms Value Source (4S,6S)-4-(Ethylamino)-5,6-dihydro-6-methyl-4HH-thieno(2,3-b)thiopyran-2-sulfonamide 7,7-dioxide monohydrochloride ChEBI (4S,6S)-4-(Ethylamino)-6-methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide hydrochloride ChEBI (4S,trans)-4-(Ethylamino)-6-methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide hydrochloride ChEBI Dorzolamide HCL ChEBI Trusopt Kegg (4S,6S)-4-(Ethylamino)-5,6-dihydro-6-methyl-4HH-thieno(2,3-b)thiopyran-2-sulphonamide 7,7-dioxide monohydrochloride Generator (4S,6S)-4-(Ethylamino)-6-methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulphonamide 7,7-dioxide hydrochloride Generator (4S,trans)-4-(Ethylamino)-6-methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulphonamide 7,7-dioxide hydrochloride Generator 4-Ethylamino-5,6-dihydro-6-methyl-7,7-dioxide-4H-thieno(2,3-b)thiopyran-2-sulfonamide MeSH 5,6-Dihydro-4-ethylamino-6-methyl-4H-thieno(2,3-b)thiopyran-2-sulfonamide-7,7-dioxide MeSH Dorzolamide MeSH Dorzolamide, (trans)-isomer MeSH Dorzolamide chibret MeSH
Chemical Formula C10 H17 ClN2 O4 S3 Average Molecular Mass 360.890 g/mol Monoisotopic Mass 360.004 g/mol CAS Registry Number 130693-82-2 IUPAC Name (2S,4S)-4-(ethylamino)-2-methyl-1,1-dioxo-2H,3H,4H-1λ⁶-thieno[2,3-b]thiopyran-6-sulfonamide hydrochloride Traditional Name dorzolamide hydrochloride SMILES Cl.[H][C@]1(C)C[C@]([H])(NCC)C2=C(SC(=C2)S(N)(=O)=O)S1(=O)=O InChI Identifier InChI=1S/C10H16N2O4S3.ClH/c1-3-12-8-4-6(2)18(13,14)10-7(8)5-9(17-10)19(11,15)16;/h5-6,8,12H,3-4H2,1-2H3,(H2,11,15,16);1H/t6-,8-;/m0./s1 InChI Key OSRUSFPMRGDLAG-QMGYSKNISA-N Chemical Taxonomy Description belongs to the class of organic compounds known as 2,3,5-trisubstituted thiophenes. These are organic compounds containing a thiophene that is trisubstituted at the C-2, C3- and C5-positions. Kingdom Organic compounds Super Class Organoheterocyclic compounds Class Thiophenes Sub Class 2,3,5-trisubstituted thiophenes Direct Parent 2,3,5-trisubstituted thiophenes Alternative Parents Substituents 2,3,5-trisubstituted thiophene
Aralkylamine
Organosulfonic acid amide
Thiopyran
Sulfone
Organic sulfonic acid or derivatives
Organosulfonic acid or derivatives
Sulfonyl
Aminosulfonyl compound
Heteroaromatic compound
Secondary aliphatic amine
Secondary amine
Organic oxygen compound
Organonitrogen compound
Organic nitrogen compound
Amine
Organosulfur compound
Organopnictogen compound
Organic oxide
Hydrochloride
Hydrocarbon derivative
Aromatic heteropolycyclic compound Molecular Framework Aromatic heteropolycyclic compounds External Descriptors 
