Record Information |
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Version | 1.0 |
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Creation Date | 2016-05-22 05:09:05 UTC |
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Update Date | 2016-11-09 01:15:46 UTC |
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Accession Number | CHEM018315 |
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Identification |
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Common Name | Guanadrel sulfate |
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Class | Small Molecule |
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Description | A sulfate salt resulting from the reaction of 2 eq. guanadrel with 1 eq. sulfuric acid. A postganglionic adrenergic blocking agent formerly used for the management of hypertension, it has been largely superseded by other drugs less likely to cause orthostatic hypotension (dizzy spells on standing up or stretching). |
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Contaminant Sources | - HMDB Contaminants - Urine
- ToxCast & Tox21 Chemicals
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Contaminant Type | Not Available |
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Chemical Structure | |
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Synonyms | Value | Source |
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Anarel | ChEBI | Bis{amino[(1,4-dioxaspiro[4.5]dec-2-ylmethyl)amino]methaniminium} sulfate | ChEBI | CL 1388R | ChEBI | CL-1388R | ChEBI | Hylorel | ChEBI | U 28288D | ChEBI | U-28,288D | ChEBI | Bis{amino[(1,4-dioxaspiro[4.5]dec-2-ylmethyl)amino]methaniminium} sulfuric acid | Generator | Bis{amino[(1,4-dioxaspiro[4.5]dec-2-ylmethyl)amino]methaniminium} sulphate | Generator | Bis{amino[(1,4-dioxaspiro[4.5]dec-2-ylmethyl)amino]methaniminium} sulphuric acid | Generator | Guanadrel sulfuric acid | Generator | Guanadrel sulphate | Generator | Guanadrel sulphuric acid | Generator | 2-(1,4-dioxaspiro[4.5]Decan-3-ylmethyl)guanidine;sulfate | Generator | 2-(1,4-dioxaspiro[4.5]Decan-3-ylmethyl)guanidine;sulphate | Generator | 2-(1,4-dioxaspiro[4.5]Decan-3-ylmethyl)guanidine;sulphuric acid | Generator | Guanadrel sulfate | MeSH | Guanadrel | MeSH |
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Chemical Formula | C20H40N6O8S |
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Average Molecular Mass | 524.630 g/mol |
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Monoisotopic Mass | 524.263 g/mol |
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CAS Registry Number | 22195-34-2 |
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IUPAC Name | bis(N-({1,4-dioxaspiro[4.5]decan-2-yl}methyl)guanidine); sulfuric acid |
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Traditional Name | bis(guanadrelum); sulfuric acid |
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SMILES | OS(O)(=O)=O.NC(=N)NCC1COC2(CCCCC2)O1.NC(=N)NCC1COC2(CCCCC2)O1 |
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InChI Identifier | InChI=1S/2C10H19N3O2.H2O4S/c2*11-9(12)13-6-8-7-14-10(15-8)4-2-1-3-5-10;1-5(2,3)4/h2*8H,1-7H2,(H4,11,12,13);(H2,1,2,3,4) |
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InChI Key | RTEVGQJRTFFMLL-UHFFFAOYSA-N |
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Chemical Taxonomy |
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Description | belongs to the class of organic compounds known as ketals. These are acetals derived from ketones by replacement of the oxo group by two hydrocarbyloxy groups R2C(OR)2 ( R not Hydrogen ). This term, once abandoned, has been reinstated as a subclass of acetals. |
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Kingdom | Organic compounds |
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Super Class | Organic oxygen compounds |
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Class | Organooxygen compounds |
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Sub Class | Ethers |
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Direct Parent | Ketals |
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Alternative Parents | |
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Substituents | - Ketal
- Sulfuric acid
- Organic sulfuric acid or derivatives
- Meta-dioxolane
- Guanidine
- Oxacycle
- Organoheterocyclic compound
- Carboximidamide
- Organic nitrogen compound
- Organopnictogen compound
- Organic oxide
- Hydrocarbon derivative
- Organonitrogen compound
- Imine
- Aliphatic heteropolycyclic compound
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Molecular Framework | Not Available |
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External Descriptors | |
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Biological Properties |
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Status | Detected and Not Quantified |
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Origin | Not Available |
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Cellular Locations | Not Available |
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Biofluid Locations | Not Available |
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Tissue Locations | Not Available |
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Pathways | Not Available |
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Applications | Not Available |
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Biological Roles | Not Available |
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Chemical Roles | Not Available |
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Physical Properties |
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State | Not Available |
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Appearance | Not Available |
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Experimental Properties | Property | Value |
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Melting Point | Not Available | Boiling Point | Not Available | Solubility | Not Available |
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Predicted Properties | |
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Spectra |
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Spectra | Spectrum Type | Description | Splash Key | View |
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Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 10V, Positive | splash10-004i-0000090000-3dc83ac78f4d896381dd | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 20V, Positive | splash10-004i-0000090000-3dc83ac78f4d896381dd | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 40V, Positive | splash10-004i-0000090000-3dc83ac78f4d896381dd | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 10V, Negative | splash10-00di-0000090000-8366537f406f62b92bb4 | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 20V, Negative | splash10-00di-0000090000-8366537f406f62b92bb4 | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 40V, Negative | splash10-00di-0000090000-8366537f406f62b92bb4 | Spectrum |
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Toxicity Profile |
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Route of Exposure | Not Available |
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Mechanism of Toxicity | Not Available |
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Metabolism | Not Available |
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Toxicity Values | Not Available |
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Lethal Dose | Not Available |
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Carcinogenicity (IARC Classification) | Not Available |
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Uses/Sources | Not Available |
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Minimum Risk Level | Not Available |
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Health Effects | Not Available |
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Symptoms | Not Available |
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Treatment | Not Available |
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Concentrations |
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| Not Available |
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External Links |
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DrugBank ID | DBSALT000889 |
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HMDB ID | Not Available |
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FooDB ID | Not Available |
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Phenol Explorer ID | Not Available |
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KNApSAcK ID | Not Available |
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BiGG ID | Not Available |
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BioCyc ID | Not Available |
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METLIN ID | Not Available |
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PDB ID | Not Available |
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Wikipedia Link | Guanadrel |
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Chemspider ID | Not Available |
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ChEBI ID | 5556 |
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PubChem Compound ID | 68552 |
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Kegg Compound ID | Not Available |
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YMDB ID | Not Available |
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ECMDB ID | Not Available |
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References |
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Synthesis Reference | Not Available |
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MSDS | Not Available |
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General References | |
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