Record Information |
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Version | 1.0 |
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Creation Date | 2016-05-22 04:40:58 UTC |
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Update Date | 2016-11-09 01:15:40 UTC |
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Accession Number | CHEM017833 |
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Identification |
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Common Name | Levosulpiride |
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Class | Small Molecule |
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Description | An optically active form of sulpiride having (S)-configuration. The active enantiomer of the racemic drug sulpiride. Selective D2-like dopamine antagonist (Ki values are ~ 0.015. ~ 0.013, 1, ~ 45 and ~ 77 muM at D2, D3, D4, D1 and D5 receptors respectively). |
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Contaminant Sources | - ToxCast & Tox21 Chemicals
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Contaminant Type | Not Available |
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Chemical Structure | |
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Synonyms | Value | Source |
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(-)-Sulpiride | ChEBI | (-)-N-(((S)-1-Ethyl-2-pyrrolidinyl)methyl)-5-sulfamoyl-O-anisamide | ChEBI | (S)-(-)-5-Aminosulfonyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-methoxybenzamide | ChEBI | (S)-(-)-N-((1-Ethyl-2-pyrrolidinyl)methyl)-5-sulfamoyl-O-anisamide | ChEBI | (S)-Sulpiride | ChEBI | Levosulpirida | ChEBI | Levosulpiride | ChEBI | Levosulpiridum | ChEBI | S-(-)-N-(1-Ethyl-2-pyrrolidinomethyl)-2-methoxy-5-sulfamoylebenzamide | ChEBI | Levopraid | Kegg | (-)-N-(((S)-1-Ethyl-2-pyrrolidinyl)methyl)-5-sulphamoyl-O-anisamide | Generator | (S)-(-)-5-Aminosulphonyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-methoxybenzamide | Generator | (S)-(-)-N-((1-Ethyl-2-pyrrolidinyl)methyl)-5-sulphamoyl-O-anisamide | Generator | S-(-)-N-(1-Ethyl-2-pyrrolidinomethyl)-2-methoxy-5-sulphamoylebenzamide | Generator | N-(((S)-1-Ethyl-2-pyrrolidinyl)methyl)-5-sulfamoyl-O-anisamide | MeSH | N-[[(2S)-1-Ethylpyrrolidin-2-yl]methyl]-2-methoxy-5-sulphamoylbenzamide | Generator |
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Chemical Formula | C15H23N3O4S |
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Average Molecular Mass | 341.430 g/mol |
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Monoisotopic Mass | 341.141 g/mol |
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CAS Registry Number | 23672-07-3 |
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IUPAC Name | N-{[(2S)-1-ethylpyrrolidin-2-yl]methyl}-2-methoxy-5-sulfamoylbenzene-1-carboximidic acid |
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Traditional Name | S-(-)-sulpiride |
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SMILES | [H][C@@]1(CN=C(O)C2=C(OC)C=CC(=C2)S(N)(=O)=O)CCCN1CC |
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InChI Identifier | InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21)/t11-/m0/s1 |
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InChI Key | BGRJTUBHPOOWDU-NSHDSACASA-N |
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Chemical Taxonomy |
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Description | belongs to the class of organic compounds known as benzenesulfonamides. These are organic compounds containing a sulfonamide group that is S-linked to a benzene ring. |
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Kingdom | Organic compounds |
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Super Class | Benzenoids |
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Class | Benzene and substituted derivatives |
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Sub Class | Benzenesulfonamides |
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Direct Parent | Benzenesulfonamides |
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Alternative Parents | |
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Substituents | - Benzenesulfonamide
- Benzamide
- Benzenesulfonyl group
- Benzoic acid or derivatives
- Phenoxy compound
- Anisole
- Benzoyl
- Methoxybenzene
- Phenol ether
- Alkyl aryl ether
- N-alkylpyrrolidine
- Organosulfonic acid amide
- Pyrrolidine
- Organic sulfonic acid or derivatives
- Organosulfonic acid or derivatives
- Aminosulfonyl compound
- Sulfonyl
- Tertiary aliphatic amine
- Tertiary amine
- Amino acid or derivatives
- Carboxamide group
- Secondary carboxylic acid amide
- Ether
- Carboxylic acid derivative
- Azacycle
- Organoheterocyclic compound
- Organooxygen compound
- Organonitrogen compound
- Organic oxygen compound
- Hydrocarbon derivative
- Organic oxide
- Organopnictogen compound
- Organosulfur compound
- Organic nitrogen compound
- Amine
- Aromatic heteromonocyclic compound
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Molecular Framework | Aromatic heteromonocyclic compounds |
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External Descriptors | |
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Biological Properties |
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Status | Detected and Not Quantified |
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Origin | Not Available |
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Cellular Locations | Not Available |
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Biofluid Locations | Not Available |
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Tissue Locations | Not Available |
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Pathways | Not Available |
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Applications | Not Available |
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Biological Roles | Not Available |
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Chemical Roles | Not Available |
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Physical Properties |
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State | Not Available |
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Appearance | Not Available |
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Experimental Properties | Property | Value |
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Melting Point | Not Available | Boiling Point | Not Available | Solubility | Not Available |
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Predicted Properties | |
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Spectra |
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Spectra | Spectrum Type | Description | Splash Key | View |
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Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 10V, Positive | splash10-01ox-0519000000-709a0cc07372655e216e | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 20V, Positive | splash10-03fr-2931000000-a4feed04814e6a775edb | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 40V, Positive | splash10-01qm-9300000000-41411c150a46fffcffd5 | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 10V, Negative | splash10-0006-0019000000-908ca17fb0c5d8ea4da3 | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 20V, Negative | splash10-01t9-6936000000-913d80650e823e5a057c | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 40V, Negative | splash10-004i-9210000000-e9d0ec345582ac120e35 | Spectrum |
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Toxicity Profile |
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Route of Exposure | Not Available |
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Mechanism of Toxicity | Not Available |
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Metabolism | Not Available |
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Toxicity Values | Not Available |
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Lethal Dose | Not Available |
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Carcinogenicity (IARC Classification) | Not Available |
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Uses/Sources | Not Available |
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Minimum Risk Level | Not Available |
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Health Effects | Not Available |
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Symptoms | Not Available |
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Treatment | Not Available |
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Concentrations |
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| Not Available |
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External Links |
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DrugBank ID | Not Available |
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HMDB ID | Not Available |
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FooDB ID | Not Available |
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Phenol Explorer ID | Not Available |
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KNApSAcK ID | Not Available |
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BiGG ID | Not Available |
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BioCyc ID | Not Available |
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METLIN ID | Not Available |
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PDB ID | Not Available |
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Wikipedia Link | Levosulpiride |
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Chemspider ID | Not Available |
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ChEBI ID | 64119 |
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PubChem Compound ID | 688272 |
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Kegg Compound ID | Not Available |
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YMDB ID | Not Available |
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ECMDB ID | Not Available |
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References |
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Synthesis Reference | Not Available |
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MSDS | Not Available |
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General References | |
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