Record Information |
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Version | 1.0 |
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Creation Date | 2016-05-22 04:28:32 UTC |
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Update Date | 2016-11-09 01:15:37 UTC |
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Accession Number | CHEM017582 |
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Identification |
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Common Name | Oxymetazoline |
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Class | Small Molecule |
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Description | A direct acting sympathomimetic used as a vasoconstrictor to relieve nasal congestion. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1251) |
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Contaminant Sources | - HMDB Contaminants - Urine
- STOFF IDENT Compounds
- ToxCast & Tox21 Chemicals
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Contaminant Type | Not Available |
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Chemical Structure | |
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Synonyms | Value | Source |
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2-(4-Tert-butyl-2,6-dimethyl-3-hydroxybenzyl)-2-imidazoline | ChEBI | 3-[(4,5-Dihydro-1H-imidazol-2-yl)methyl]-6-(1,1-dimethylethyl)-2,4-dimethylphenol | ChEBI | 6-t-Butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimethylphenol | ChEBI | 6-Tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimethylphenol | ChEBI | Oxymetazolina | ChEBI | Oxymetazolinum | ChEBI | Afrin | Kegg | Operil | Kegg | Oximetazolinum | HMDB | Oxymetazoline hydrochloride crystalline | HMDB | Oxymethazoline | HMDB | Oxymetozoline | HMDB | Hydrochloride, oxymetazoline | HMDB | Oxymetazoline hydrochloride | HMDB |
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Chemical Formula | C16H24N2O |
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Average Molecular Mass | 260.375 g/mol |
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Monoisotopic Mass | 260.189 g/mol |
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CAS Registry Number | 1491-59-4 |
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IUPAC Name | 6-tert-butyl-3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethylphenol |
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Traditional Name | oxymetazoline |
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SMILES | CC1=CC(=C(O)C(C)=C1CC1=NCCN1)C(C)(C)C |
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InChI Identifier | InChI=1S/C16H24N2O/c1-10-8-13(16(3,4)5)15(19)11(2)12(10)9-14-17-6-7-18-14/h8,19H,6-7,9H2,1-5H3,(H,17,18) |
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InChI Key | WYWIFABBXFUGLM-UHFFFAOYSA-N |
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Chemical Taxonomy |
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Description | belongs to the class of organic compounds known as xylenols. These are aromatic compounds that contain a xylene moiety, which is a monocyclic benzene carrying exactly two methyl groups, and at least one hydroxyl group. |
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Kingdom | Organic compounds |
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Super Class | Benzenoids |
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Class | Benzene and substituted derivatives |
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Sub Class | Xylenes |
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Direct Parent | Xylenols |
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Alternative Parents | |
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Substituents | - Xylenol
- Phenylpropane
- M-xylene
- O-cresol
- P-cresol
- Phenol
- Imidolactam
- 2-imidazoline
- Amidine
- Carboxylic acid amidine
- Azacycle
- Organoheterocyclic compound
- Organic 1,3-dipolar compound
- Propargyl-type 1,3-dipolar organic compound
- Carboximidamide
- Organic nitrogen compound
- Hydrocarbon derivative
- Organooxygen compound
- Organonitrogen compound
- Organopnictogen compound
- Organic oxygen compound
- Aromatic heteromonocyclic compound
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Molecular Framework | Aromatic heteromonocyclic compounds |
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External Descriptors | |
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Biological Properties |
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Status | Detected and Not Quantified |
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Origin | Not Available |
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Cellular Locations | Not Available |
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Biofluid Locations | Not Available |
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Tissue Locations | Not Available |
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Pathways | Not Available |
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Applications | Not Available |
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Biological Roles | Not Available |
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Chemical Roles | Not Available |
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Physical Properties |
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State | Not Available |
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Appearance | Not Available |
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Experimental Properties | Property | Value |
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Melting Point | Not Available | Boiling Point | Not Available | Solubility | Not Available |
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Predicted Properties | |
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Spectra |
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Spectra | Spectrum Type | Description | Splash Key | View |
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Predicted GC-MS | Predicted GC-MS Spectrum - GC-MS (Non-derivatized) - 70eV, Positive | splash10-004m-3970000000-ee2ec321a55bc78173e1 | Spectrum | Predicted GC-MS | Predicted GC-MS Spectrum - GC-MS (1 TMS) - 70eV, Positive | splash10-01di-9847000000-0444f6bbf25ec5a41405 | Spectrum | Predicted GC-MS | Predicted GC-MS Spectrum - GC-MS (Non-derivatized) - 70eV, Positive | Not Available | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 10V, Positive | splash10-03di-0090000000-c488f3b0f9552a4b7dfc | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 20V, Positive | splash10-03di-1290000000-a18cdab404c55b4e4497 | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 40V, Positive | splash10-0006-7960000000-1c8f2a11df7638b325df | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 10V, Negative | splash10-0a4i-0090000000-fd2fa239fe46b8ca41c0 | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 20V, Negative | splash10-0a4i-1090000000-0e91b1578606ee50752f | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 40V, Negative | splash10-01r6-4890000000-3e6c50f85057e4ad43d2 | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 10V, Positive | splash10-03di-0190000000-d99fec2889c2b1f7a321 | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 20V, Positive | splash10-03dr-1970000000-c0fcd30c275a95baee23 | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 40V, Positive | splash10-0596-6910000000-b96b7ef48bcbbf6173b0 | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 10V, Negative | splash10-0a4i-0090000000-7c4aa654b272455d2904 | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 20V, Negative | splash10-0a6r-0970000000-1e55ae3560aa333e78fa | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 40V, Negative | splash10-00ac-0930000000-4066d357ff89a3ee1206 | Spectrum |
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Toxicity Profile |
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Route of Exposure | Not Available |
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Mechanism of Toxicity | Not Available |
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Metabolism | Not Available |
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Toxicity Values | Not Available |
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Lethal Dose | Not Available |
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Carcinogenicity (IARC Classification) | Not Available |
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Uses/Sources | Not Available |
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Minimum Risk Level | Not Available |
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Health Effects | Not Available |
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Symptoms | Not Available |
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Treatment | Not Available |
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Concentrations |
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| Not Available |
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External Links |
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DrugBank ID | DB00935 |
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HMDB ID | HMDB0015070 |
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FooDB ID | Not Available |
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Phenol Explorer ID | Not Available |
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KNApSAcK ID | Not Available |
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BiGG ID | Not Available |
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BioCyc ID | Not Available |
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METLIN ID | Not Available |
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PDB ID | Not Available |
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Wikipedia Link | Oxymetazoline |
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Chemspider ID | 4475 |
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ChEBI ID | 7862 |
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PubChem Compound ID | 4636 |
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Kegg Compound ID | C07363 |
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YMDB ID | Not Available |
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ECMDB ID | Not Available |
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References |
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Synthesis Reference | Not Available |
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MSDS | Not Available |
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General References | |
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