Record Information |
---|
Version | 1.0 |
---|
Creation Date | 2016-05-22 04:27:17 UTC |
---|
Update Date | 2016-11-09 01:15:37 UTC |
---|
Accession Number | CHEM017545 |
---|
Identification |
---|
Common Name | Dimercaprol |
---|
Class | Small Molecule |
---|
Description | A dithiol that is propane-1,2-dithiol in which one of the methyl hydrogens is replaced by a hydroxy group. a chelating agent originally developed during World War II as an experimental antidote against the arsenic-based poison gas Lewisite, it has been used clinically since 1949 for the treatment of poisoning by arsenic, mercury and gold. It can also be used for treatment of poisoning by antimony, bismuth and possibly thallium, and (with sodium calcium edetate) in cases of acute leaad poisoning. Administration is by (painful) intramuscular injection of a suspension of dimercaprol in peanut oil, typically every 4 hours for 2-10 days depending on the toxicity. In the past, dimercaprol was also used for the treatment of Wilson's disease, a severely debilitating genetic disorder in which the body tends to retain copper, with resultant liver and brain injury. |
---|
Contaminant Sources | - HMDB Contaminants - Urine
- STOFF IDENT Compounds
- ToxCast & Tox21 Chemicals
|
---|
Contaminant Type | Not Available |
---|
Chemical Structure | |
---|
Synonyms | Value | Source |
---|
1,2-Dimercapto-3-propanol | ChEBI | 1,2-Dithioglycerol | ChEBI | 2,3-Dimercapto-1-propanol | ChEBI | 2,3-Dimercaptol-1-propanol | ChEBI | 2,3-Dimercaptopropanol | ChEBI | 2,3-Dithiopropanol | ChEBI | 2,3-Mercaptopropan-1-ol | ChEBI | 2,3-Mercaptopropanol | ChEBI | 3-Hydroxy-1,2-propanedithiol | ChEBI | alpha,beta-Dithioglycerol | ChEBI | BAL | ChEBI | British anti-lewisite | ChEBI | British antilewisite | ChEBI | Dimercaprolum | ChEBI | Dimercaptopropanol | ChEBI | Dithioglycerine | ChEBI | Dithioglycerol | ChEBI | Sulfactin | ChEBI | a,b-Dithioglycerol | Generator | Α,β-dithioglycerol | Generator | Sulphactin | Generator | 2,3-Dimercapro | HMDB | 2,3 Dithiopropan 1 O1 | HMDB | 2,3-Dimercaptopropanol, cadmium | HMDB | Cadmium 2,3-dimercaptopropanol | HMDB | Taylor brand OF dimercaprol | HMDB | 2,3 Dimercaptopropanol | HMDB | Anti-lewisite agent, british | HMDB | British anti lewisite agent | HMDB | British anti-lewisite agent | HMDB | Knoll brand OF dimercaprol | HMDB | BAL in oil | HMDB | British anti lewisite | HMDB | Cadmium 2,3 dimercaptopropanol | HMDB | Dicaptol | HMDB | 2,3-Dithiopropan-1-O1 | HMDB | Anti-lewisite, british | HMDB | B.A.L. | HMDB | In oil, bal | HMDB | Oil, bal in | HMDB |
|
---|
Chemical Formula | C3H8OS2 |
---|
Average Molecular Mass | 124.225 g/mol |
---|
Monoisotopic Mass | 124.002 g/mol |
---|
CAS Registry Number | 59-52-9 |
---|
IUPAC Name | 2,3-disulfanylpropan-1-ol |
---|
Traditional Name | dimercaprol |
---|
SMILES | OCC(S)CS |
---|
InChI Identifier | InChI=1S/C3H8OS2/c4-1-3(6)2-5/h3-6H,1-2H2 |
---|
InChI Key | WQABCVAJNWAXTE-UHFFFAOYSA-N |
---|
Chemical Taxonomy |
---|
Description | belongs to the class of organic compounds known as alkylthiols. These are organic compounds containing the thiol functional group linked to an alkyl chain. |
---|
Kingdom | Organic compounds |
---|
Super Class | Organosulfur compounds |
---|
Class | Thiols |
---|
Sub Class | Alkylthiols |
---|
Direct Parent | Alkylthiols |
---|
Alternative Parents | |
---|
Substituents | - Alkylthiol
- Organic oxygen compound
- Hydrocarbon derivative
- Primary alcohol
- Organooxygen compound
- Alcohol
- Aliphatic acyclic compound
|
---|
Molecular Framework | Aliphatic acyclic compounds |
---|
External Descriptors | |
---|
Biological Properties |
---|
Status | Detected and Not Quantified |
---|
Origin | Not Available |
---|
Cellular Locations | Not Available |
---|
Biofluid Locations | Not Available |
---|
Tissue Locations | Not Available |
---|
Pathways | Not Available |
---|
Applications | Not Available |
---|
Biological Roles | Not Available |
---|
Chemical Roles | Not Available |
---|
Physical Properties |
---|
State | Not Available |
---|
Appearance | Not Available |
---|
Experimental Properties | Property | Value |
---|
Melting Point | Not Available | Boiling Point | Not Available | Solubility | Not Available |
|
---|
Predicted Properties | |
---|
Spectra |
---|
Spectra | Spectrum Type | Description | Splash Key | View |
---|
Predicted GC-MS | Predicted GC-MS Spectrum - GC-MS (Non-derivatized) - 70eV, Positive | splash10-0006-9000000000-02d345f6932e4df7ae4c | Spectrum | Predicted GC-MS | Predicted GC-MS Spectrum - GC-MS (1 TMS) - 70eV, Positive | splash10-00ds-9600000000-5c06a4ce37d095db5a1c | Spectrum | Predicted GC-MS | Predicted GC-MS Spectrum - GC-MS (Non-derivatized) - 70eV, Positive | Not Available | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 10V, Positive | splash10-056r-2900000000-5e1d01085e00977775ac | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 20V, Positive | splash10-0a6u-7900000000-2010199887988b9b1f5e | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 40V, Positive | splash10-05fr-9100000000-e15a808f41fdd35de8fe | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 10V, Negative | splash10-008i-9300000000-b6482fcdaeab876341d3 | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 20V, Negative | splash10-0acc-9200000000-f38fb9fba80629c643ff | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 40V, Negative | splash10-0a5c-9000000000-975b939359caaed4e935 | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 10V, Positive | splash10-0adl-7900000000-9b2eced4f80479d4220b | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 20V, Positive | splash10-0596-9000000000-dfbf45f840944602d259 | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 40V, Positive | splash10-05fr-9000000000-f9a12c59d4f73bb8e6e3 | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 10V, Negative | splash10-00di-0900000000-b6d4cfef7736df5ca9d2 | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 20V, Negative | splash10-001l-9000000000-12de67a14d053353befb | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 40V, Negative | splash10-000x-9000000000-72344935882f89d86e04 | Spectrum | 1D NMR | 1H NMR Spectrum | Not Available | Spectrum | 1D NMR | 13C NMR Spectrum | Not Available | Spectrum | 1D NMR | 1H NMR Spectrum | Not Available | Spectrum | 1D NMR | 13C NMR Spectrum | Not Available | Spectrum | 1D NMR | 1H NMR Spectrum | Not Available | Spectrum | 1D NMR | 13C NMR Spectrum | Not Available | Spectrum | 1D NMR | 1H NMR Spectrum | Not Available | Spectrum | 1D NMR | 13C NMR Spectrum | Not Available | Spectrum | 1D NMR | 1H NMR Spectrum | Not Available | Spectrum | 1D NMR | 13C NMR Spectrum | Not Available | Spectrum | 1D NMR | 1H NMR Spectrum | Not Available | Spectrum | 1D NMR | 13C NMR Spectrum | Not Available | Spectrum | 1D NMR | 1H NMR Spectrum | Not Available | Spectrum | 1D NMR | 13C NMR Spectrum | Not Available | Spectrum | 1D NMR | 1H NMR Spectrum | Not Available | Spectrum | 1D NMR | 13C NMR Spectrum | Not Available | Spectrum | 1D NMR | 1H NMR Spectrum | Not Available | Spectrum | 1D NMR | 13C NMR Spectrum | Not Available | Spectrum | 1D NMR | 1H NMR Spectrum | Not Available | Spectrum | 1D NMR | 13C NMR Spectrum | Not Available | Spectrum |
|
---|
Toxicity Profile |
---|
Route of Exposure | Not Available |
---|
Mechanism of Toxicity | Not Available |
---|
Metabolism | Not Available |
---|
Toxicity Values | Not Available |
---|
Lethal Dose | Not Available |
---|
Carcinogenicity (IARC Classification) | Not Available |
---|
Uses/Sources | Not Available |
---|
Minimum Risk Level | Not Available |
---|
Health Effects | Not Available |
---|
Symptoms | Not Available |
---|
Treatment | Not Available |
---|
Concentrations |
---|
| Not Available |
---|
External Links |
---|
DrugBank ID | DB06782 |
---|
HMDB ID | HMDB0015677 |
---|
FooDB ID | Not Available |
---|
Phenol Explorer ID | Not Available |
---|
KNApSAcK ID | Not Available |
---|
BiGG ID | Not Available |
---|
BioCyc ID | Not Available |
---|
METLIN ID | Not Available |
---|
PDB ID | Not Available |
---|
Wikipedia Link | Dimercaprol |
---|
Chemspider ID | 2971 |
---|
ChEBI ID | 64198 |
---|
PubChem Compound ID | 3080 |
---|
Kegg Compound ID | C02924 |
---|
YMDB ID | Not Available |
---|
ECMDB ID | ECMDB20229 |
---|
References |
---|
Synthesis Reference | Not Available |
---|
MSDS | Not Available |
---|
General References | |
---|