Record Information |
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Version | 1.0 |
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Creation Date | 2016-05-22 03:46:49 UTC |
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Update Date | 2016-11-09 01:15:29 UTC |
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Accession Number | CHEM016895 |
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Identification |
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Common Name | Syrosingopine |
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Class | Small Molecule |
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Description | Not Available |
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Contaminant Sources | - ToxCast & Tox21 Chemicals
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Contaminant Type | Not Available |
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Chemical Structure | |
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Synonyms | Value | Source |
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Siringina | Kegg | Methyl (1R,15S,17R,18R,19S,20S)-17-{4-[(ethoxycarbonyl)oxy]-3,5-dimethoxybenzoyloxy}-6,18-dimethoxy-3,13-diazapentacyclo[11.8.0.0,.0,.0,]henicosa-2(10),4(9),5,7-tetraene-19-carboxylic acid | Generator | Syringopine | MeSH | Methyl (1R,15S,17R,18R,19S,20S)-17-{4-[(ethoxycarbonyl)oxy]-3,5-dimethoxybenzoyloxy}-6,18-dimethoxy-3,13-diazapentacyclo[11.8.0.0²,¹⁰.0⁴,⁹.0¹⁵,²⁰]henicosa-2(10),4(9),5,7-tetraene-19-carboxylic acid | Generator |
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Chemical Formula | C35H42N2O11 |
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Average Molecular Mass | 666.724 g/mol |
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Monoisotopic Mass | 666.279 g/mol |
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CAS Registry Number | 84-36-6 |
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IUPAC Name | methyl (1R,15S,17R,18R,19S,20S)-17-{4-[(ethoxycarbonyl)oxy]-3,5-dimethoxybenzoyloxy}-6,18-dimethoxy-3,13-diazapentacyclo[11.8.0.0²,¹⁰.0⁴,⁹.0¹⁵,²⁰]henicosa-2(10),4(9),5,7-tetraene-19-carboxylate |
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Traditional Name | syrosingopine |
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SMILES | [H][C@@]12CN3CCC4=C(NC5=C4C=CC(OC)=C5)[C@@]3([H])C[C@]1([H])[C@]([H])(C(=O)OC)[C@@]([H])(OC)[C@@]([H])(C2)OC(=O)C1=CC(OC)=C(OC(=O)OCC)C(OC)=C1 |
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InChI Identifier | InChI=1S/C35H42N2O11/c1-7-46-35(40)48-31-26(42-3)12-18(13-27(31)43-4)33(38)47-28-14-19-17-37-11-10-22-21-9-8-20(41-2)15-24(21)36-30(22)25(37)16-23(19)29(32(28)44-5)34(39)45-6/h8-9,12-13,15,19,23,25,28-29,32,36H,7,10-11,14,16-17H2,1-6H3/t19-,23+,25-,28-,29+,32+/m1/s1 |
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InChI Key | ZCDNRPPFBQDQHR-SSYATKPKSA-N |
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Chemical Taxonomy |
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Description | belongs to the class of organic compounds known as yohimbine alkaloids. These are alkaloids containing the pentacyclic yohimban skeleton. The Yohimbinoid alkaloids contain a carbocyclic ring E arising through C-17 to C-18 bond formation in a corynantheine precursor. |
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Kingdom | Organic compounds |
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Super Class | Alkaloids and derivatives |
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Class | Yohimbine alkaloids |
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Sub Class | Not Available |
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Direct Parent | Yohimbine alkaloids |
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Alternative Parents | |
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Substituents | - Yohimbine
- Corynanthean skeleton
- Yohimbine alkaloid
- Beta-carboline
- Pyridoindole
- Gallic acid or derivatives
- M-methoxybenzoic acid or derivatives
- Benzoate ester
- M-dimethoxybenzene
- Dimethoxybenzene
- 3-alkylindole
- Indole
- Indole or derivatives
- Benzoic acid or derivatives
- Phenoxy compound
- Anisole
- Phenol ether
- Methoxybenzene
- Benzoyl
- Alkyl aryl ether
- Aralkylamine
- Piperidine
- Carbonic acid diester
- Monocyclic benzene moiety
- Dicarboxylic acid or derivatives
- Benzenoid
- Pyrrole
- Heteroaromatic compound
- Methyl ester
- Tertiary amine
- Carboxylic acid ester
- Carbonic acid derivative
- Tertiary aliphatic amine
- Amino acid or derivatives
- Azacycle
- Organoheterocyclic compound
- Carboxylic acid derivative
- Ether
- Dialkyl ether
- Organooxygen compound
- Amine
- Organic nitrogen compound
- Hydrocarbon derivative
- Organic oxide
- Organonitrogen compound
- Carbonyl group
- Organic oxygen compound
- Organopnictogen compound
- Aromatic heteropolycyclic compound
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Molecular Framework | Aromatic heteropolycyclic compounds |
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External Descriptors | Not Available |
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Biological Properties |
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Status | Detected and Not Quantified |
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Origin | Not Available |
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Cellular Locations | Not Available |
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Biofluid Locations | Not Available |
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Tissue Locations | Not Available |
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Pathways | Not Available |
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Applications | Not Available |
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Biological Roles | Not Available |
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Chemical Roles | Not Available |
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Physical Properties |
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State | Not Available |
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Appearance | Not Available |
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Experimental Properties | Property | Value |
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Melting Point | Not Available | Boiling Point | Not Available | Solubility | Not Available |
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Predicted Properties | |
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Spectra |
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Spectra | Spectrum Type | Description | Splash Key | View |
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Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 10V, Positive | splash10-0171-0033059000-cd45d7761a5bb5c6ad03 | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 20V, Positive | splash10-0002-2555098000-6633953209f80c8634c0 | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 40V, Positive | splash10-053r-2913061000-58f261b5afc84b5c5a80 | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 10V, Negative | splash10-014i-2020019000-b98b60489684885da61d | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 20V, Negative | splash10-00y0-9010077000-924bb3d1074fed57e425 | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 40V, Negative | splash10-004j-3923233000-07b860052c0b71815f02 | Spectrum |
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Toxicity Profile |
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Route of Exposure | Not Available |
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Mechanism of Toxicity | Not Available |
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Metabolism | Not Available |
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Toxicity Values | Not Available |
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Lethal Dose | Not Available |
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Carcinogenicity (IARC Classification) | Not Available |
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Uses/Sources | Not Available |
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Minimum Risk Level | Not Available |
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Health Effects | Not Available |
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Symptoms | Not Available |
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Treatment | Not Available |
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Concentrations |
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| Not Available |
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External Links |
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DrugBank ID | Not Available |
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HMDB ID | Not Available |
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FooDB ID | Not Available |
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Phenol Explorer ID | Not Available |
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KNApSAcK ID | Not Available |
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BiGG ID | Not Available |
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BioCyc ID | Not Available |
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METLIN ID | Not Available |
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PDB ID | Not Available |
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Wikipedia Link | Not Available |
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Chemspider ID | Not Available |
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ChEBI ID | Not Available |
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PubChem Compound ID | 6769 |
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Kegg Compound ID | Not Available |
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YMDB ID | Not Available |
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ECMDB ID | Not Available |
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References |
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Synthesis Reference | Not Available |
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MSDS | Not Available |
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General References | Not Available |
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