Record Information |
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Version | 1.0 |
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Creation Date | 2016-05-22 03:45:49 UTC |
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Update Date | 2016-11-09 01:15:29 UTC |
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Accession Number | CHEM016863 |
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Identification |
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Common Name | Rescinnamine |
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Class | Small Molecule |
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Description | Rescinnamine is an angiotensin-converting enzyme inhibitor used as an antihypertensive drug. It is an alkaloid obtained from _Rauwolfia serpentina_ and other species of _Rauwolfia_. |
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Contaminant Sources | - HMDB Contaminants - Urine
- STOFF IDENT Compounds
- ToxCast & Tox21 Chemicals
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Contaminant Type | Not Available |
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Chemical Structure | |
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Synonyms | Value | Source |
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Methyl trimethoxycinnamoylreserpate | HMDB | Recinnamine | HMDB | Rescinnamin | HMDB | Reserpinene | HMDB | Reserpinin | HMDB | Reserpinine | HMDB | Trimethoxycinnamoyl methyl reserpate | HMDB |
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Chemical Formula | C35H42N2O9 |
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Average Molecular Mass | 634.716 g/mol |
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Monoisotopic Mass | 634.289 g/mol |
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CAS Registry Number | 24815-24-5 |
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IUPAC Name | methyl (1R,15S,17R,18R,19S,20S)-6,18-dimethoxy-17-{[3-(3,4,5-trimethoxyphenyl)prop-2-enoyl]oxy}-3,13-diazapentacyclo[11.8.0.0²,¹⁰.0⁴,⁹.0¹⁵,²⁰]henicosa-2(10),4(9),5,7-tetraene-19-carboxylate |
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Traditional Name | rescinnamine |
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SMILES | [H][C@]12C[C@@H](OC(=O)C=CC3=CC(OC)=C(OC)C(OC)=C3)[C@H](OC)[C@@H](C(=O)OC)[C@@]1([H])C[C@@]1([H])N(CCC3=C1NC1=C3C=CC(OC)=C1)C2 |
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InChI Identifier | InChI=1S/C35H42N2O9/c1-40-21-8-9-22-23-11-12-37-18-20-15-29(46-30(38)10-7-19-13-27(41-2)33(43-4)28(14-19)42-3)34(44-5)31(35(39)45-6)24(20)17-26(37)32(23)36-25(22)16-21/h7-10,13-14,16,20,24,26,29,31,34,36H,11-12,15,17-18H2,1-6H3/t20-,24+,26-,29-,31+,34+/m1/s1 |
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InChI Key | SZLZWPPUNLXJEA-LAFLMMDJSA-N |
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Chemical Taxonomy |
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Description | belongs to the class of organic compounds known as yohimbine alkaloids. These are alkaloids containing the pentacyclic yohimban skeleton. The Yohimbinoid alkaloids contain a carbocyclic ring E arising through C-17 to C-18 bond formation in a corynantheine precursor. |
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Kingdom | Organic compounds |
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Super Class | Alkaloids and derivatives |
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Class | Yohimbine alkaloids |
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Sub Class | Not Available |
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Direct Parent | Yohimbine alkaloids |
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Alternative Parents | |
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Substituents | - Yohimbine
- Corynanthean skeleton
- Yohimbine alkaloid
- Pyridoindole
- Beta-carboline
- Cinnamic acid or derivatives
- Coumaric acid or derivatives
- Cinnamic acid ester
- 3-alkylindole
- Indole or derivatives
- Indole
- Styrene
- Methoxybenzene
- Anisole
- Phenoxy compound
- Phenol ether
- Fatty acid ester
- Alkyl aryl ether
- Aralkylamine
- Dicarboxylic acid or derivatives
- Benzenoid
- Monocyclic benzene moiety
- Piperidine
- Fatty acyl
- Heteroaromatic compound
- Alpha,beta-unsaturated carboxylic ester
- Enoate ester
- Methyl ester
- Pyrrole
- Tertiary amine
- Amino acid or derivatives
- Tertiary aliphatic amine
- Carboxylic acid ester
- Carboxylic acid derivative
- Ether
- Azacycle
- Dialkyl ether
- Organoheterocyclic compound
- Organic oxygen compound
- Carbonyl group
- Organic oxide
- Organopnictogen compound
- Hydrocarbon derivative
- Organic nitrogen compound
- Amine
- Organooxygen compound
- Organonitrogen compound
- Aromatic heteropolycyclic compound
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Molecular Framework | Aromatic heteropolycyclic compounds |
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External Descriptors | Not Available |
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Biological Properties |
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Status | Detected and Not Quantified |
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Origin | Not Available |
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Cellular Locations | Not Available |
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Biofluid Locations | Not Available |
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Tissue Locations | Not Available |
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Pathways | Not Available |
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Applications | Not Available |
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Biological Roles | Not Available |
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Chemical Roles | Not Available |
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Physical Properties |
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State | Not Available |
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Appearance | Not Available |
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Experimental Properties | Property | Value |
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Melting Point | Not Available | Boiling Point | Not Available | Solubility | Not Available |
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Predicted Properties | |
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Spectra |
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Spectra | Spectrum Type | Description | Splash Key | View |
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Predicted GC-MS | Predicted GC-MS Spectrum - GC-MS (Non-derivatized) - 70eV, Positive | splash10-007p-0469134000-22e085a00ac52f1a3fc4 | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 10V, Positive | splash10-0079-0033209000-ee873b6b010ae1decc8c | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 20V, Positive | splash10-00xs-0379405000-82705d2979450611dc45 | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 40V, Positive | splash10-0pj0-3559003000-62945eb088df2981f749 | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 10V, Negative | splash10-001i-0031209000-69bd23b15cb07f5f5bc2 | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 20V, Negative | splash10-0i0s-0258429000-07d3b407787494d1c141 | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 40V, Negative | splash10-000t-0549211000-fe6752c4b31c0e6bce52 | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 10V, Positive | splash10-0079-0042009000-3f55aeb201794c3d5500 | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 20V, Positive | splash10-0079-0451019000-95ecd82537f2ede2cae9 | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 40V, Positive | splash10-0ukd-0931021000-36cc3bd5905e4017f7cf | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 10V, Negative | splash10-001i-0010009000-4efc2ba750ec5d3d3b4e | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 20V, Negative | splash10-00dr-0110094000-9f95afa9be8d5fe523c3 | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 40V, Negative | splash10-056a-1212191000-9673c536103f8fc8f464 | Spectrum |
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Toxicity Profile |
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Route of Exposure | Not Available |
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Mechanism of Toxicity | Not Available |
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Metabolism | Not Available |
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Toxicity Values | Not Available |
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Lethal Dose | Not Available |
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Carcinogenicity (IARC Classification) | Not Available |
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Uses/Sources | Not Available |
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Minimum Risk Level | Not Available |
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Health Effects | Not Available |
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Symptoms | Not Available |
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Treatment | Not Available |
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Concentrations |
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| Not Available |
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External Links |
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DrugBank ID | DB01180 |
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HMDB ID | HMDB0015311 |
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FooDB ID | Not Available |
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Phenol Explorer ID | Not Available |
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KNApSAcK ID | C00001762 |
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BiGG ID | Not Available |
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BioCyc ID | Not Available |
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METLIN ID | Not Available |
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PDB ID | Not Available |
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Wikipedia Link | Rescinnamine |
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Chemspider ID | 30295 |
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ChEBI ID | 28572 |
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PubChem Compound ID | 5280954 |
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Kegg Compound ID | C06540 |
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YMDB ID | Not Available |
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ECMDB ID | Not Available |
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References |
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Synthesis Reference | Not Available |
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MSDS | Not Available |
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General References | Not Available |
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