Record Information |
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Version | 1.0 |
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Creation Date | 2016-05-22 03:43:32 UTC |
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Update Date | 2016-11-09 01:15:28 UTC |
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Accession Number | CHEM016782 |
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Identification |
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Common Name | Methylprednisolone acetate |
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Class | Small Molecule |
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Description | An acetate ester resulting from the formal condensation of the 21-hydroxy function of 6alpha-methylprednisolone compound with acetic acid. |
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Contaminant Sources | - ToxCast & Tox21 Chemicals
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Contaminant Type | Not Available |
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Chemical Structure | |
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Synonyms | Value | Source |
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11beta,17,21-Trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione 21-acetate | ChEBI | 6alpha-Methylprednisolone 21-acetate | ChEBI | 6alpha-Methylprednisolone acetate | ChEBI | Depo-medrol | ChEBI | Depo-methylprednisolone acetate | ChEBI | m-Predrol | ChEBI | Methylprednisolone 21-acetate | ChEBI | 11b,17,21-Trihydroxy-6a-methylpregna-1,4-diene-3,20-dione 21-acetate | Generator | 11b,17,21-Trihydroxy-6a-methylpregna-1,4-diene-3,20-dione 21-acetic acid | Generator | 11beta,17,21-Trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione 21-acetic acid | Generator | 11Β,17,21-trihydroxy-6α-methylpregna-1,4-diene-3,20-dione 21-acetate | Generator | 11Β,17,21-trihydroxy-6α-methylpregna-1,4-diene-3,20-dione 21-acetic acid | Generator | 6a-Methylprednisolone 21-acetate | Generator | 6a-Methylprednisolone 21-acetic acid | Generator | 6alpha-Methylprednisolone 21-acetic acid | Generator | 6Α-methylprednisolone 21-acetate | Generator | 6Α-methylprednisolone 21-acetic acid | Generator | 6a-Methylprednisolone acetate | Generator | 6a-Methylprednisolone acetic acid | Generator | 6alpha-Methylprednisolone acetic acid | Generator | 6Α-methylprednisolone acetate | Generator | 6Α-methylprednisolone acetic acid | Generator | Depo-methylprednisolone acetic acid | Generator | Methylprednisolone 21-acetic acid | Generator | Methylprednisolone acetic acid | Generator | [2-[(6S,8S,9S,10R,11S,13S,14S,17R)-11,17-Dihydroxy-6,10,13-trimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetic acid | Generator | Methylprednisolone acetate | MeSH | Methylprednisolone acetate, (11beta,16alpha)-isomer | MeSH | Methylprednisolone-21-acetate | MeSH | Acetyl-methylprednisolone | MeSH | Methylprednisolone acetate, (11beta,16beta)-isomer | MeSH | depo-Medrone | MeSH |
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Chemical Formula | C24H32O6 |
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Average Molecular Mass | 416.514 g/mol |
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Monoisotopic Mass | 416.220 g/mol |
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CAS Registry Number | 53-36-1 |
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IUPAC Name | 2-[(1S,2R,8S,10S,11S,14R,15S,17S)-14,17-dihydroxy-2,8,15-trimethyl-5-oxotetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadeca-3,6-dien-14-yl]-2-oxoethyl acetate |
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Traditional Name | depo-medrol |
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SMILES | [H][C@@]12CC[C@](O)(C(=O)COC(C)=O)[C@@]1(C)C[C@]([H])(O)[C@@]1([H])[C@@]2([H])C[C@]([H])(C)C2=CC(=O)C=C[C@]12C |
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InChI Identifier | InChI=1S/C24H32O6/c1-13-9-16-17-6-8-24(29,20(28)12-30-14(2)25)23(17,4)11-19(27)21(16)22(3)7-5-15(26)10-18(13)22/h5,7,10,13,16-17,19,21,27,29H,6,8-9,11-12H2,1-4H3/t13-,16-,17-,19-,21+,22-,23-,24-/m0/s1 |
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InChI Key | PLBHSZGDDKCEHR-LFYFAGGJSA-N |
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Chemical Taxonomy |
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Description | belongs to the class of organic compounds known as gluco/mineralocorticoids, progestogins and derivatives. These are steroids with a structure based on a hydroxylated prostane moiety. |
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Kingdom | Organic compounds |
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Super Class | Lipids and lipid-like molecules |
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Class | Steroids and steroid derivatives |
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Sub Class | Pregnane steroids |
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Direct Parent | Gluco/mineralocorticoids, progestogins and derivatives |
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Alternative Parents | |
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Substituents | - Progestogin-skeleton
- 20-oxosteroid
- 3-oxo-delta-1,4-steroid
- 3-oxosteroid
- 17-hydroxysteroid
- 11-hydroxysteroid
- 11-beta-hydroxysteroid
- Hydroxysteroid
- Oxosteroid
- Delta-1,4-steroid
- Alpha-acyloxy ketone
- Alpha-hydroxy ketone
- Tertiary alcohol
- Cyclic alcohol
- Ketone
- Cyclic ketone
- Carboxylic acid ester
- Secondary alcohol
- Carboxylic acid derivative
- Monocarboxylic acid or derivatives
- Organic oxygen compound
- Carbonyl group
- Hydrocarbon derivative
- Alcohol
- Organooxygen compound
- Organic oxide
- Aliphatic homopolycyclic compound
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Molecular Framework | Aliphatic homopolycyclic compounds |
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External Descriptors | |
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Biological Properties |
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Status | Detected and Not Quantified |
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Origin | Not Available |
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Cellular Locations | Not Available |
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Biofluid Locations | Not Available |
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Tissue Locations | Not Available |
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Pathways | Not Available |
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Applications | Not Available |
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Biological Roles | Not Available |
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Chemical Roles | Not Available |
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Physical Properties |
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State | Not Available |
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Appearance | Not Available |
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Experimental Properties | Property | Value |
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Melting Point | Not Available | Boiling Point | Not Available | Solubility | Not Available |
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Predicted Properties | |
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Spectra |
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Spectra | Spectrum Type | Description | Splash Key | View |
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LC-MS/MS | LC-MS/MS Spectrum - LC-ESI-qTof , Positive | splash10-0gw1-0797000000-d1887e3160a98e711a98 | Spectrum | LC-MS/MS | LC-MS/MS Spectrum - LC-ESI-qTof , Positive | splash10-0f72-0889100000-fdcb13410e4528ac916a | Spectrum | LC-MS/MS | LC-MS/MS Spectrum - , positive | splash10-0gw1-0797000000-d1887e3160a98e711a98 | Spectrum | LC-MS/MS | LC-MS/MS Spectrum - , positive | splash10-0f72-0889100000-fdcb13410e4528ac916a | Spectrum | LC-MS/MS | LC-MS/MS Spectrum - , positive | splash10-03dr-3960000000-8700b8836d2bf65e620a | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 10V, Positive | splash10-00kb-1019200000-c3371497914460d2b010 | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 20V, Positive | splash10-0a4s-0229000000-16f935fa13ce51646fa7 | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 40V, Positive | splash10-00rw-3791000000-aa90746b0fd20a51c37d | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 10V, Negative | splash10-0aor-9005500000-d53da8dc6d22e5be4be6 | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 20V, Negative | splash10-0a4i-9014000000-f2807f6ecf92d896e018 | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 40V, Negative | splash10-0a4i-9012000000-1b7647cf48e8b9dfda6f | Spectrum |
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Toxicity Profile |
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Route of Exposure | Not Available |
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Mechanism of Toxicity | Not Available |
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Metabolism | Not Available |
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Toxicity Values | Not Available |
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Lethal Dose | Not Available |
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Carcinogenicity (IARC Classification) | Not Available |
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Uses/Sources | Not Available |
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Minimum Risk Level | Not Available |
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Health Effects | Not Available |
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Symptoms | Not Available |
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Treatment | Not Available |
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Concentrations |
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External Links |
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DrugBank ID | DBSALT001157 |
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HMDB ID | Not Available |
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FooDB ID | Not Available |
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Phenol Explorer ID | Not Available |
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KNApSAcK ID | Not Available |
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BiGG ID | Not Available |
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BioCyc ID | Not Available |
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METLIN ID | Not Available |
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PDB ID | Not Available |
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Wikipedia Link | Methylprednisolone acetate |
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Chemspider ID | Not Available |
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ChEBI ID | 6889 |
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PubChem Compound ID | 5877 |
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Kegg Compound ID | C08179 |
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YMDB ID | Not Available |
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ECMDB ID | Not Available |
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References |
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Synthesis Reference | Not Available |
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MSDS | Not Available |
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General References | Not Available |
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