| Record Information |
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| Version | 1.0 |
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| Creation Date | 2016-05-22 03:41:20 UTC |
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| Update Date | 2016-11-09 01:15:27 UTC |
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| Accession Number | CHEM016717 |
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| Identification |
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| Common Name | Foscarnet trisodium |
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| Class | Small Molecule |
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| Description | The trisodium salt of phosphonoformic acid. It is used as an antiviral agent in the treatment of cytomegalovirus retinitis (CMV retinitis, an inflamation of the retina that can lead to blindness) and as an alternative to ganciclovir for AIDS patients who require concurrent antiretroviral therapy but are unable to tolerate ganciclovir due to haematological toxicity. |
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| Contaminant Sources | - HMDB Contaminants - Urine
- STOFF IDENT Compounds
- ToxCast & Tox21 Chemicals
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| Contaminant Type | Not Available |
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| Chemical Structure | |
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| Synonyms | | Value | Source |
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| Foscarnet sodique | ChEBI | | FOSCARNET sodium | ChEBI | | Foscarneto sodico | ChEBI | | Foscarnetum natricum | ChEBI | | Trisodium carboxyphosphate | ChEBI | | Trisodium carboxyphosphate (anhydrous) | ChEBI | | Trisodium dioxidophosphinecarboxylate oxide | ChEBI | | Trisodium phosphonoformate (anhydrous) | ChEBI | | Foscavir | Kegg | | Trisodium carboxyphosphoric acid | Generator | | Trisodium carboxyphosphoric acid (anhydrous) | Generator | | Trisodium dioxidophosphinecarboxylic acid oxide | Generator | | Trisodium phosphonoformic acid (anhydrous) | Generator | | Trisodium phosphonoformic acid | Generator | | Foscarnet tripotassium salt | MeSH | | Foscarnet manganese (2+) (2:3) salt | MeSH | | Foscarnet barium (2:3) salt | MeSH | | Foscarnet trisodium salt | MeSH | | Foscarnet calcium (2:3) salt | MeSH | | Foscarnet | MeSH | | Foscarnet trilithium salt | MeSH | | Foscarnet sodium hexahydrate | MeSH | | Foscarnet magnesium (2:3) salt | MeSH | | Phosphonoformic acid | MeSH | | Phosphonoformate | MeSH | | Foscarnet disodium salt | MeSH | | Disodium salt, foscarnet | MeSH | | Phosphonoformate, trisodium | MeSH | | Sodium, foscarnet | MeSH | | Sodium hexahydrate, foscarnet | MeSH | | Hexahydrate, foscarnet sodium | MeSH | | Trilithium salt, foscarnet | MeSH | | Tripotassium salt, foscarnet | MeSH | | Trisodium salt, foscarnet | MeSH | | Trisodium phosphonoformate | MeSH |
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| Chemical Formula | CNa3O5P |
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| Average Molecular Mass | 191.951 g/mol |
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| Monoisotopic Mass | 191.918 g/mol |
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| CAS Registry Number | 63585-09-1 |
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| IUPAC Name | trisodium phosphonatoformate |
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| Traditional Name | trisodium foscarnet(3-) |
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| SMILES | [Na+].[Na+].[Na+].[O-]C(=O)P([O-])([O-])=O |
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| InChI Identifier | InChI=1S/CH3O5P.3Na/c2-1(3)7(4,5)6;;;/h(H,2,3)(H2,4,5,6);;;/q;3*+1/p-3 |
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| InChI Key | DFHAXXVZCFXGOQ-UHFFFAOYSA-K |
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| Chemical Taxonomy |
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| Description | belongs to the class of organic compounds known as organic phosphonic acids. These are organic compounds containing phosphonic acid. |
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| Kingdom | Organic compounds |
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| Super Class | Organic acids and derivatives |
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| Class | Organic phosphonic acids and derivatives |
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| Sub Class | Organic phosphonic acids |
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| Direct Parent | Organic phosphonic acids |
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| Alternative Parents | |
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| Substituents | - Organophosphonic acid
- Carbonic acid derivative
- Organic alkali metal salt
- Organic oxygen compound
- Organopnictogen compound
- Organic oxide
- Hydrocarbon derivative
- Organic sodium salt
- Organic salt
- Organophosphorus compound
- Organooxygen compound
- Aliphatic acyclic compound
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| Molecular Framework | Aliphatic acyclic compounds |
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| External Descriptors | |
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| Biological Properties |
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| Status | Detected and Not Quantified |
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| Origin | Not Available |
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| Cellular Locations | Not Available |
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| Biofluid Locations | Not Available |
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| Tissue Locations | Not Available |
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| Pathways | Not Available |
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| Applications | Not Available |
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| Biological Roles | Not Available |
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| Chemical Roles | Not Available |
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| Physical Properties |
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| State | Not Available |
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| Appearance | Not Available |
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| Experimental Properties | | Property | Value |
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| Melting Point | Not Available | | Boiling Point | Not Available | | Solubility | Not Available |
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| Predicted Properties | |
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| Spectra |
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| Spectra | | Spectrum Type | Description | Splash Key | View |
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| Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 10V, Positive | splash10-0006-0900000000-ba0cfa4dc4f50ae25d73 | Spectrum | | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 20V, Positive | splash10-0006-0900000000-ba0cfa4dc4f50ae25d73 | Spectrum | | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 40V, Positive | splash10-0006-0900000000-ba0cfa4dc4f50ae25d73 | Spectrum |
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| Toxicity Profile |
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| Route of Exposure | Not Available |
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| Mechanism of Toxicity | Not Available |
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| Metabolism | Not Available |
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| Toxicity Values | Not Available |
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| Lethal Dose | Not Available |
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| Carcinogenicity (IARC Classification) | Not Available |
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| Uses/Sources | Not Available |
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| Minimum Risk Level | Not Available |
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| Health Effects | Not Available |
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| Symptoms | Not Available |
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| Treatment | Not Available |
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| Concentrations |
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| Not Available |
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| External Links |
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| DrugBank ID | DBSALT000200 |
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| HMDB ID | Not Available |
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| FooDB ID | Not Available |
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| Phenol Explorer ID | Not Available |
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| KNApSAcK ID | Not Available |
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| BiGG ID | Not Available |
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| BioCyc ID | Not Available |
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| METLIN ID | Not Available |
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| PDB ID | Not Available |
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| Wikipedia Link | Not Available |
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| Chemspider ID | Not Available |
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| ChEBI ID | 141644 |
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| PubChem Compound ID | 44561 |
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| Kegg Compound ID | Not Available |
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| YMDB ID | Not Available |
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| ECMDB ID | Not Available |
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| References |
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| Synthesis Reference | Not Available |
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| MSDS | Not Available |
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| General References | Not Available |
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