Record Information |
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Version | 1.0 |
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Creation Date | 2016-05-22 03:39:58 UTC |
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Update Date | 2016-11-09 01:15:27 UTC |
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Accession Number | CHEM016670 |
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Identification |
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Common Name | Dimetacrine |
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Class | Small Molecule |
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Description | Dimetacrine is also known as dimethacrine or acripamine. It is marketed under the names Istonil, Istonyl, Linostil, and Miroistonil. Dimetacrine is a tricyclic antidepressant (TCA) with imipramine-like effects used in Europe for the treatment of depression. Dimetacrine is no longer used in Japan. |
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Contaminant Sources | - STOFF IDENT Compounds
- ToxCast & Tox21 Chemicals
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Contaminant Type | Not Available |
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Chemical Structure | |
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Synonyms | Value | Source |
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10-(3-(Dimethylamino)propyl)-9,9-dimethylacridan tartrate | MeSH | 3-(9,9-Dimethyl-10(9H)-acridinyl)-N,N-dimethyl-1-propanamine | MeSH | Dimetacrine bitartate | MeSH | Dimetacrine tartate | MeSH | Dimethacrine | MeSH | Dimethacrine tartrate | MeSH | Dimethacrine tartrate, (1:1)(R-(r*,r*))-isomer | MeSH | Istonil | MeSH | Miroistonil | MeSH | Isotonil | MeSH |
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Chemical Formula | C20H26N2 |
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Average Molecular Mass | 294.434 g/mol |
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Monoisotopic Mass | 294.210 g/mol |
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CAS Registry Number | 4757-55-5 |
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IUPAC Name | [3-(9,9-dimethyl-9,10-dihydroacridin-10-yl)propyl]dimethylamine |
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Traditional Name | dimetacrine |
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SMILES | CN(C)CCCN1C2=CC=CC=C2C(C)(C)C2=CC=CC=C12 |
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InChI Identifier | InChI=1S/C20H26N2/c1-20(2)16-10-5-7-12-18(16)22(15-9-14-21(3)4)19-13-8-6-11-17(19)20/h5-8,10-13H,9,14-15H2,1-4H3 |
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InChI Key | RYQOGSFEJBUZBX-UHFFFAOYSA-N |
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Chemical Taxonomy |
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Description | belongs to the class of organic compounds known as acridines. These are organic compounds containing the acridine moiety, a linear tricyclic heterocycle which consists of two benzene rings joined by a pyridine ring. |
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Kingdom | Organic compounds |
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Super Class | Organoheterocyclic compounds |
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Class | Quinolines and derivatives |
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Sub Class | Benzoquinolines |
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Direct Parent | Acridines |
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Alternative Parents | |
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Substituents | - Acridine
- Alkyldiarylamine
- Tertiary aliphatic/aromatic amine
- Benzenoid
- Tertiary aliphatic amine
- Tertiary amine
- Azacycle
- Organic nitrogen compound
- Organopnictogen compound
- Hydrocarbon derivative
- Organonitrogen compound
- Amine
- Aromatic heteropolycyclic compound
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Molecular Framework | Aromatic heteropolycyclic compounds |
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External Descriptors | Not Available |
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Biological Properties |
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Status | Detected and Not Quantified |
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Origin | Not Available |
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Cellular Locations | Not Available |
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Biofluid Locations | Not Available |
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Tissue Locations | Not Available |
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Pathways | Not Available |
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Applications | Not Available |
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Biological Roles | Not Available |
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Chemical Roles | Not Available |
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Physical Properties |
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State | Not Available |
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Appearance | Not Available |
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Experimental Properties | Property | Value |
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Melting Point | Not Available | Boiling Point | Not Available | Solubility | Not Available |
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Predicted Properties | |
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Spectra |
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Spectra | Spectrum Type | Description | Splash Key | View |
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Predicted GC-MS | Predicted GC-MS Spectrum - GC-MS (Non-derivatized) - 70eV, Positive | splash10-0a4i-9580000000-a0b4b0a04fe5d685c54d | Spectrum | Predicted GC-MS | Predicted GC-MS Spectrum - GC-MS (Non-derivatized) - 70eV, Positive | Not Available | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 10V, Positive | splash10-0002-1090000000-f1ec989b044f9c24d5bd | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 20V, Positive | splash10-0f72-5090000000-1633096ac4395c74338e | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 40V, Positive | splash10-000f-9130000000-eb4f001b2bd55e81c50a | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 10V, Negative | splash10-0006-0090000000-d1f3a00dc93e3e42dbd5 | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 20V, Negative | splash10-052f-0090000000-e69ae99ca00798b20846 | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 40V, Negative | splash10-0aor-2790000000-99e516e9016bfd8f01f9 | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 10V, Positive | splash10-0002-0090000000-19fde7b235562f81ace5 | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 20V, Positive | splash10-0002-1090000000-72b162b3d9dc56876d50 | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 40V, Positive | splash10-0a4i-9360000000-6b017f602090f565ab8f | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 10V, Negative | splash10-0006-0090000000-d7e41f50346ef7ead2a6 | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 20V, Negative | splash10-0006-0090000000-1b4ca5fb6e195df60ca3 | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 40V, Negative | splash10-052f-0790000000-3ea1bf32911269e8d62b | Spectrum |
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Toxicity Profile |
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Route of Exposure | Not Available |
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Mechanism of Toxicity | Not Available |
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Metabolism | Not Available |
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Toxicity Values | Not Available |
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Lethal Dose | Not Available |
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Carcinogenicity (IARC Classification) | Not Available |
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Uses/Sources | Not Available |
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Minimum Risk Level | Not Available |
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Health Effects | Not Available |
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Symptoms | Not Available |
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Treatment | Not Available |
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Concentrations |
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| Not Available |
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External Links |
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DrugBank ID | DB08996 |
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HMDB ID | HMDB0251373 |
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FooDB ID | Not Available |
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Phenol Explorer ID | Not Available |
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KNApSAcK ID | Not Available |
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BiGG ID | Not Available |
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BioCyc ID | Not Available |
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METLIN ID | Not Available |
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PDB ID | Not Available |
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Wikipedia Link | Dimetacrine |
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Chemspider ID | 85085 |
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ChEBI ID | Not Available |
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PubChem Compound ID | 94280 |
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Kegg Compound ID | Not Available |
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YMDB ID | Not Available |
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ECMDB ID | Not Available |
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References |
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Synthesis Reference | Not Available |
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MSDS | Not Available |
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General References | Not Available |
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