Record Information |
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Version | 1.0 |
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Creation Date | 2016-05-22 03:38:22 UTC |
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Update Date | 2016-11-09 01:15:26 UTC |
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Accession Number | CHEM016608 |
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Identification |
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Common Name | Carminomycin |
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Class | Small Molecule |
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Description | A toxic anthracycline antibiotic that is produced by Actinomadura carminata and also has potent antineoplastic activity. |
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Contaminant Sources | - ToxCast & Tox21 Chemicals
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Contaminant Type | Not Available |
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Chemical Structure | |
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Synonyms | Value | Source |
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Carubicin | ChEBI | CCRIS 961 | ChEBI | Karminomycin | ChEBI | O-Demethyldaunomycin | ChEBI | Carminomicin | MeSH | Carminomycin II | MeSH | Hydrochloride, carubicin | MeSH | Rubeomycin a1 | MeSH | Carminomycin I | MeSH | Demethyldaunomycin | MeSH | Carminomycin III | MeSH | Demethyldaunorubicin | MeSH | Rubeomycin a | MeSH | Carubicin hydrochloride | MeSH | Karminomicin | MeSH |
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Chemical Formula | C26H27NO10 |
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Average Molecular Mass | 513.499 g/mol |
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Monoisotopic Mass | 513.163 g/mol |
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CAS Registry Number | 50935-04-1 |
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IUPAC Name | (8S,10S)-8-acetyl-10-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy}-1,6,8,11-tetrahydroxy-5,7,8,9,10,12-hexahydrotetracene-5,12-dione |
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Traditional Name | carminomycin |
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SMILES | [H][C@]1(N)C[C@]([H])(O[C@@]2([H])C[C@@](O)(CC3=C(O)C4=C(C(O)=C23)C(=O)C2=C(C=CC=C2O)C4=O)C(C)=O)O[C@@]([H])(C)[C@@]1([H])O |
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InChI Identifier | InChI=1S/C26H27NO10/c1-9-21(30)13(27)6-16(36-9)37-15-8-26(35,10(2)28)7-12-18(15)25(34)20-19(23(12)32)22(31)11-4-3-5-14(29)17(11)24(20)33/h3-5,9,13,15-16,21,29-30,32,34-35H,6-8,27H2,1-2H3/t9-,13-,15-,16-,21+,26-/m0/s1 |
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InChI Key | XREUEWVEMYWFFA-CSKJXFQVSA-N |
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Chemical Taxonomy |
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Description | belongs to the class of organic compounds known as anthracyclines. These are polyketides containing a tetracenequinone ring structure with a sugar attached by glycosidic linkage. |
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Kingdom | Organic compounds |
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Super Class | Phenylpropanoids and polyketides |
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Class | Anthracyclines |
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Sub Class | Not Available |
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Direct Parent | Anthracyclines |
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Alternative Parents | |
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Substituents | - Anthracycline
- Anthracyclinone-skeleton
- Aminoglycoside core
- Tetracenequinone
- 9,10-anthraquinone
- 1,4-anthraquinone
- Anthracene
- Hexose monosaccharide
- Glycosyl compound
- O-glycosyl compound
- Tetralin
- Aryl ketone
- Amino saccharide
- 1-hydroxy-4-unsubstituted benzenoid
- 1-hydroxy-2-unsubstituted benzenoid
- Benzenoid
- Monosaccharide
- Oxane
- Tertiary alcohol
- Alpha-hydroxy ketone
- Vinylogous acid
- Secondary alcohol
- 1,2-aminoalcohol
- Ketone
- Polyol
- Organoheterocyclic compound
- Acetal
- Oxacycle
- Alcohol
- Carbonyl group
- Organic oxide
- Organopnictogen compound
- Organic oxygen compound
- Hydrocarbon derivative
- Primary aliphatic amine
- Organic nitrogen compound
- Amine
- Organonitrogen compound
- Primary amine
- Organooxygen compound
- Aromatic heteropolycyclic compound
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Molecular Framework | Aromatic heteropolycyclic compounds |
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External Descriptors | |
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Biological Properties |
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Status | Detected and Not Quantified |
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Origin | Not Available |
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Cellular Locations | Not Available |
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Biofluid Locations | Not Available |
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Tissue Locations | Not Available |
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Pathways | Not Available |
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Applications | Not Available |
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Biological Roles | Not Available |
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Chemical Roles | Not Available |
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Physical Properties |
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State | Not Available |
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Appearance | Not Available |
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Experimental Properties | Property | Value |
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Melting Point | Not Available | Boiling Point | Not Available | Solubility | Not Available |
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Predicted Properties | |
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Spectra |
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Spectra | Spectrum Type | Description | Splash Key | View |
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Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 10V, Positive | splash10-03y1-0009640000-34d19b4f5d8c12af8e7f | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 20V, Positive | splash10-014r-0319100000-ba8046944f882fb30aea | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 40V, Positive | splash10-014i-6239000000-14d7102b462bb57eb98a | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 10V, Negative | splash10-03di-1106490000-39f06fccf321ebc6d072 | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 20V, Negative | splash10-001l-2109400000-2c91fca3d223bba58a7f | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 40V, Negative | splash10-001i-3109000000-1031d4a1fb1f8e3929a9 | Spectrum |
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Toxicity Profile |
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Route of Exposure | Not Available |
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Mechanism of Toxicity | Not Available |
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Metabolism | Not Available |
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Toxicity Values | Not Available |
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Lethal Dose | Not Available |
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Carcinogenicity (IARC Classification) | Not Available |
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Uses/Sources | Not Available |
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Minimum Risk Level | Not Available |
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Health Effects | Not Available |
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Symptoms | Not Available |
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Treatment | Not Available |
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Concentrations |
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| Not Available |
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External Links |
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DrugBank ID | Not Available |
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HMDB ID | Not Available |
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FooDB ID | Not Available |
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Phenol Explorer ID | Not Available |
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KNApSAcK ID | Not Available |
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BiGG ID | Not Available |
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BioCyc ID | CPD-15734 |
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METLIN ID | Not Available |
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PDB ID | Not Available |
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Wikipedia Link | Carubicin |
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Chemspider ID | Not Available |
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ChEBI ID | 31359 |
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PubChem Compound ID | 443831 |
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Kegg Compound ID | C12432 |
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YMDB ID | Not Available |
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ECMDB ID | Not Available |
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References |
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Synthesis Reference | Not Available |
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MSDS | Not Available |
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General References | |
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