Identification Common Name Astromicin Class Small Molecule Description An amino cyclitol glycoside that is L-chiro-inositol in which the hydroxy groups at positions 1, 4, and 6 are replaced by aminoacetyl)methylamino, amino, and methoxy groups, respectively, and in which the hydroxy group at position 3 is converted to the corresponding 2,6-diamino-2,3,4,6,7-pentadeoxy-beta-L-lyxo-heptopyranoside. The major component of fortimicin, obtained from Micromonospora olivasterospora. It is administered (as the sulfate salt) by intramuscular injection or intravenous infusion for the treatment of severe systemic infections due to sensitive Gram-negative organisms. Contaminant Sources ToxCast & Tox21 Chemicals Contaminant Type Not Available Chemical Structure Synonyms Value Source 4-Amino-1-((aminoacetyl)methylamino)-1,4-dideoxy-3-O-(2,6-diamino-2,3,4,6,7-pentadeoxy-beta-L-lyxo-heptopyranosyl)-6-O-methyl-L-chiro-inositol ChEBI 4-Amino-1-(2-amino-N-methylacetamido)-1,4-dideoxy-3-O-(2,6-diamino-2,3,4,6,7-pentadeoxy-beta-L-lyxo-heptopyranosyl)-6-O-methyl-L-chiro-inositol ChEBI Antibiotic KW-1070 ChEBI ASTM ChEBI Astromicina ChEBI Astromicine ChEBI Astromicinum ChEBI Astromycin ChEBI Fortimicin a ChEBI KW 1070 ChEBI KW-1070 ChEBI XK 70-1 ChEBI XK-70-1 ChEBI 4-Amino-1-((aminoacetyl)methylamino)-1,4-dideoxy-3-O-(2,6-diamino-2,3,4,6,7-pentadeoxy-b-L-lyxo-heptopyranosyl)-6-O-methyl-L-chiro-inositol Generator 4-Amino-1-((aminoacetyl)methylamino)-1,4-dideoxy-3-O-(2,6-diamino-2,3,4,6,7-pentadeoxy-β-L-lyxo-heptopyranosyl)-6-O-methyl-L-chiro-inositol Generator 4-Amino-1-(2-amino-N-methylacetamido)-1,4-dideoxy-3-O-(2,6-diamino-2,3,4,6,7-pentadeoxy-b-L-lyxo-heptopyranosyl)-6-O-methyl-L-chiro-inositol Generator 4-Amino-1-(2-amino-N-methylacetamido)-1,4-dideoxy-3-O-(2,6-diamino-2,3,4,6,7-pentadeoxy-β-L-lyxo-heptopyranosyl)-6-O-methyl-L-chiro-inositol Generator Abbott 44747 MeSH Astromicin MeSH Fortimicin a sulfate MeSH Fortimicin a sulfate (1:2) MeSH
Chemical Formula C17 H35 N5 O6 Average Molecular Mass 405.496 g/mol Monoisotopic Mass 405.259 g/mol CAS Registry Number 55779-06-1 IUPAC Name 2-amino-N-[(1S,2R,3R,4S,5S,6R)-4-amino-3-{[(2R,3R,6S)-3-amino-6-[(1S)-1-aminoethyl]oxan-2-yl]oxy}-2,5-dihydroxy-6-methoxycyclohexyl]-N-methylacetamide Traditional Name astromicin SMILES [H][C@@](C)(N)[C@]1([H])CC[C@@]([H])(N)[C@@]([H])(O[C@]2([H])[C@@]([H])(N)[C@]([H])(O)[C@]([H])(OC)[C@@]([H])(N(C)C(=O)CN)[C@@]2([H])O)O1 InChI Identifier InChI=1S/C17H35N5O6/c1-7(19)9-5-4-8(20)17(27-9)28-15-11(21)13(24)16(26-3)12(14(15)25)22(2)10(23)6-18/h7-9,11-17,24-25H,4-6,18-21H2,1-3H3/t7-,8+,9-,11-,12-,13-,14+,15+,16+,17+/m0/s1 InChI Key BIDUPMYXGFNAEJ-APGVDKLISA-N Chemical Taxonomy Description belongs to the class of organic compounds known as aminocyclitol glycosides. These are organic compounds containing an amicocyclitol moiety glycosidically linked to a carbohydrate moiety. There are two major classes of aminoglycosides containing a 2-streptamine core. They are called 4,5- and 4,6-disubstituted 2-deoxystreptamines. Kingdom Organic compounds Super Class Organic oxygen compounds Class Organooxygen compounds Sub Class Carbohydrates and carbohydrate conjugates Direct Parent Aminocyclitol glycosides Alternative Parents Substituents Amino cyclitol glycoside
Alpha-amino acid amide
Alpha-amino acid or derivatives
Aminocyclitol or derivatives
Cyclohexanol
Cyclohexylamine
Cyclitol or derivatives
Oxane
Cyclic alcohol
Tertiary carboxylic acid amide
1,2-aminoalcohol
Amino acid or derivatives
Carboxamide group
Secondary alcohol
Ether
Dialkyl ether
Organoheterocyclic compound
Carboxylic acid derivative
Acetal
Oxacycle
Organonitrogen compound
Carbonyl group
Hydrocarbon derivative
Organic oxide
Alcohol
Amine
Organopnictogen compound
Organic nitrogen compound
Primary amine
Primary aliphatic amine
Aliphatic heteromonocyclic compound Molecular Framework Aliphatic heteromonocyclic compounds External Descriptors 
