Record Information |
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Version | 1.0 |
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Creation Date | 2016-05-22 03:37:14 UTC |
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Update Date | 2016-11-09 01:15:26 UTC |
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Accession Number | CHEM016567 |
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Identification |
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Common Name | Anisindione |
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Class | Small Molecule |
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Description | Anisindione is a synthetic anticoagulant and an indanedione derivative. Its anticoagulant action is mediated through the inhibition of the vitamin K-mediated gamma-carboxylation of precursor proteins that are critical in forming the formation of active procoagulation factors II, VII, IX, and X, as well as the anticoagulant proteins C and S, in the liver. |
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Contaminant Sources | - HMDB Contaminants - Urine
- ToxCast & Tox21 Chemicals
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Contaminant Type | Not Available |
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Chemical Structure | |
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Synonyms | Value | Source |
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2-(4-Methoxyphenyl)-1H-indene-1,3(2H)-dione | ChEBI | 2-(4-Methoxyphenyl)indan-1,3-dione | ChEBI | 2-(p-Methoxyphenyl)-1,3-indandione | ChEBI | 2-(p-Methoxyphenyl)indane-1,3-dione | ChEBI | 2-p-Anisyl-1,3-indandione | ChEBI | 2-Para-anisyl-1,3-indandione | ChEBI | Anisin indandione | ChEBI | Anisindiona | ChEBI | Anisindionum | ChEBI | Miradon | Kegg |
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Chemical Formula | C16H12O3 |
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Average Molecular Mass | 252.265 g/mol |
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Monoisotopic Mass | 252.079 g/mol |
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CAS Registry Number | 117-37-3 |
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IUPAC Name | 2-(4-methoxyphenyl)-2,3-dihydro-1H-indene-1,3-dione |
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Traditional Name | anisindione |
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SMILES | COC1=CC=C(C=C1)C1C(=O)C2=CC=CC=C2C1=O |
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InChI Identifier | InChI=1S/C16H12O3/c1-19-11-8-6-10(7-9-11)14-15(17)12-4-2-3-5-13(12)16(14)18/h2-9,14H,1H3 |
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InChI Key | XRCFXMGQEVUZFC-UHFFFAOYSA-N |
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Chemical Taxonomy |
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Description | belongs to the class of organic compounds known as indanediones. Indanediones are compounds containing an indane ring bearing two ketone groups. |
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Kingdom | Organic compounds |
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Super Class | Benzenoids |
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Class | Indanes |
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Sub Class | Indanones |
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Direct Parent | Indanediones |
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Alternative Parents | |
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Substituents | - Indanedione
- Phenoxy compound
- Anisole
- Methoxybenzene
- Aryl alkyl ketone
- Aryl ketone
- Phenol ether
- Alkyl aryl ether
- 1,3-diketone
- Monocyclic benzene moiety
- 1,3-dicarbonyl compound
- Ketone
- Ether
- Hydrocarbon derivative
- Organic oxygen compound
- Organooxygen compound
- Organic oxide
- Aromatic homopolycyclic compound
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Molecular Framework | Aromatic homopolycyclic compounds |
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External Descriptors | |
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Biological Properties |
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Status | Detected and Not Quantified |
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Origin | Not Available |
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Cellular Locations | Not Available |
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Biofluid Locations | Not Available |
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Tissue Locations | Not Available |
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Pathways | Not Available |
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Applications | Not Available |
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Biological Roles | Not Available |
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Chemical Roles | Not Available |
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Physical Properties |
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State | Not Available |
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Appearance | Not Available |
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Experimental Properties | Property | Value |
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Melting Point | Not Available | Boiling Point | Not Available | Solubility | Not Available |
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Predicted Properties | |
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Spectra |
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Spectra | Spectrum Type | Description | Splash Key | View |
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Predicted GC-MS | Predicted GC-MS Spectrum - GC-MS (Non-derivatized) - 70eV, Positive | splash10-0pi0-2970000000-3072f4dff3d83d6798e0 | Spectrum | Predicted GC-MS | Predicted GC-MS Spectrum - GC-MS (Non-derivatized) - 70eV, Positive | Not Available | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 10V, Positive | splash10-0udi-0090000000-9a00a2012741ee8d529d | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 20V, Positive | splash10-0udi-0290000000-ae6d022536ede61e9a68 | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 40V, Positive | splash10-0zfr-5970000000-697cb6e17075d45c94f8 | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 10V, Negative | splash10-0udi-0090000000-1e24bd40cb0266b81059 | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 20V, Negative | splash10-0udi-0090000000-db4a7df8621482e26e27 | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 40V, Negative | splash10-000i-1490000000-17630a8bb2f337db9f2c | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 10V, Positive | splash10-0udi-0090000000-8d91e33e4298322ba53d | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 20V, Positive | splash10-0udi-0690000000-5f01d86cb0ff3819b608 | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 40V, Positive | splash10-004i-9510000000-c5661b94b65978419e91 | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 10V, Negative | splash10-0udi-0090000000-aedd17caff57899b7eff | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 20V, Negative | splash10-0udi-0090000000-de3608db6e681e51eb8b | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 40V, Negative | splash10-0532-0940000000-2d549322c6ad1c2373b4 | Spectrum |
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Toxicity Profile |
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Route of Exposure | Not Available |
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Mechanism of Toxicity | Not Available |
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Metabolism | Not Available |
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Toxicity Values | Not Available |
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Lethal Dose | Not Available |
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Carcinogenicity (IARC Classification) | Not Available |
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Uses/Sources | Not Available |
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Minimum Risk Level | Not Available |
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Health Effects | Not Available |
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Symptoms | Not Available |
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Treatment | Not Available |
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Concentrations |
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| Not Available |
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External Links |
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DrugBank ID | DB01125 |
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HMDB ID | HMDB0015257 |
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FooDB ID | Not Available |
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Phenol Explorer ID | Not Available |
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KNApSAcK ID | Not Available |
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BiGG ID | Not Available |
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BioCyc ID | Not Available |
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METLIN ID | Not Available |
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PDB ID | Not Available |
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Wikipedia Link | Anisindione |
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Chemspider ID | 2112 |
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ChEBI ID | 133809 |
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PubChem Compound ID | 2197 |
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Kegg Compound ID | Not Available |
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YMDB ID | Not Available |
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ECMDB ID | Not Available |
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References |
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Synthesis Reference | Not Available |
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MSDS | Not Available |
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General References | |
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