Silane (CHEM004463)

IdentificationTaxonomyBiological PropertiesPhysical PropertiesToxicity ProfileSpectraConcentrationsLinksReferencesXML
Record Information
Version1.0
Creation Date2016-05-19 01:45:59 UTC
Update Date2016-11-09 01:09:21 UTC
Accession NumberCHEM004463
Identification
Common NameSilane
ClassSmall Molecule
Description
Contaminant Sources
  • Clean Air Act Chemicals
  • HPV EPA Chemicals
Contaminant TypeNot Available
Chemical Structure
Thumb
MOLSDFPDBSMILESInChI
Synonyms
ValueSource
Si(4+)ChEBI
SiHMDB
SilicaHMDB
SilicateHMDB
Silicic acidHMDB
Chemical FormulaH4Si
Average Molecular Mass32.117 g/mol
Monoisotopic Mass32.008 g/mol
CAS Registry Number7803-62-5
IUPAC Namesilicon(4+) ion
Traditional Namesilicon(4+) ion
SMILES[SiH4]
InChI IdentifierInChI=1S/H4Si/h1H4
InChI KeyBLRPTPMANUNPDV-UHFFFAOYSA-N
Chemical Taxonomy
Description belongs to the class of inorganic compounds known as homogeneous metalloid compounds. These are inorganic compounds containing only metal atoms,with the largest atom being a metalloid atom.
KingdomInorganic compounds
Super ClassHomogeneous metal compounds
ClassHomogeneous metalloid compounds
Sub ClassNot Available
Direct ParentHomogeneous metalloid compounds
Alternative ParentsNot Available
Substituents
  • Homogeneous metalloid
Molecular FrameworkNot Available
External Descriptors
Biological Properties
StatusDetected and Not Quantified
OriginNot Available
Cellular LocationsNot Available
Biofluid LocationsNot Available
Tissue LocationsNot Available
PathwaysNot Available
ApplicationsNot Available
Biological RolesNot Available
Chemical RolesNot Available
Physical Properties
StateNot Available
AppearanceNot Available
Experimental Properties
PropertyValue
Melting PointNot Available
Boiling PointNot Available
SolubilityNot Available
Predicted Properties
PropertyValueSource
logP0.045ChemAxon
Physiological Charge4ChemAxon
Hydrogen Acceptor Count0ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area0 ŲChemAxon
Rotatable Bond Count0ChemAxon
Refractivity0 m³·mol⁻¹ChemAxon
Polarizability1.78 ųChemAxon
Number of Rings0ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterNoChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleNoChemAxon
Spectra
SpectraNot Available
Toxicity Profile
Route of ExposureNot Available
Mechanism of ToxicityNot Available
MetabolismNot Available
Toxicity ValuesNot Available
Lethal DoseNot Available
Carcinogenicity (IARC Classification)Not Available
Uses/SourcesNot Available
Minimum Risk LevelNot Available
Health EffectsNot Available
SymptomsNot Available
TreatmentNot Available
Concentrations
Not Available
DrugBank IDNot Available
HMDB IDHMDB0002175
FooDB IDFDB003713
Phenol Explorer IDNot Available
KNApSAcK IDNot Available
BiGG IDNot Available
BioCyc IDNot Available
METLIN IDNot Available
PDB IDNot Available
Wikipedia LinkSilicon
Chemspider ID3296906
ChEBI ID30584
PubChem Compound ID4082203
Kegg Compound IDC06263
YMDB IDNot Available
ECMDB IDNot Available
References
Synthesis ReferenceNot Available
MSDSNot Available
General References
1. Nielsen FH: How should dietary guidance be given for mineral elements with beneficial actions or suspected of being essential? J Nutr. 1996 Sep;126(9 Suppl):2377S-2385S.
2. Epstein E: The anomaly of silicon in plant biology. Proc Natl Acad Sci U S A. 1994 Jan 4;91(1):11-7.
3. Uthus EO, Seaborn CD: Deliberations and evaluations of the approaches, endpoints and paradigms for dietary recommendations of the other trace elements. J Nutr. 1996 Sep;126(9 Suppl):2452S-2459S.
4. Jones LH: Mineral components of plant cell walls. Am J Clin Nutr. 1978 Oct;31(10 Suppl):S94-S98.
5. Powell JJ, McNaughton SA, Jugdaohsingh R, Anderson SH, Dear J, Khot F, Mowatt L, Gleason KL, Sykes M, Thompson RP, Bolton-Smith C, Hodson MJ: A provisional database for the silicon content of foods in the United Kingdom. Br J Nutr. 2005 Nov;94(5):804-12.
6. Porter AE: Nanoscale characterization of the interface between bone and hydroxyapatite implants and the effect of silicon on bone apposition. Micron. 2006;37(8):681-8. Epub 2006 Mar 31.
7. Jugdaohsingh R: Silicon and bone health. J Nutr Health Aging. 2007 Mar-Apr;11(2):99-110.
8. Showell GA, Mills JS: Chemistry challenges in lead optimization: silicon isosteres in drug discovery. Drug Discov Today. 2003 Jun 15;8(12):551-6.
9. Bains W, Tacke R: Silicon chemistry as a novel source of chemical diversity in drug design. Curr Opin Drug Discov Devel. 2003 Jul;6(4):526-43.
10. Shanklin DR, Smalley DL: The immunopathology of siliconosis. History, clinical presentation, and relation to silicosis and the chemistry of silicon and silicone. Immunol Res. 1998;18(3):125-73.