Record Information |
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Version | 1.0 |
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Creation Date | 2016-05-19 01:32:34 UTC |
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Update Date | 2016-11-09 01:09:16 UTC |
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Accession Number | CHEM004020 |
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Identification |
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Common Name | CFC-12 |
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Class | Small Molecule |
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Description | Dichlorodifluoromethane is a direct contact freezing agent for foods. Refrigerant, aerosol propellant Dichlorodifluoromethane (R-12), usually sold under the brand name Freon-12, is a chlorofluorocarbon halomethane (CFC), used as a refrigerant and aerosol spray propellant. Complying with the Montreal Protocol, its manufacture was banned in the United States along with many other countries in 1994 due to concerns about damage to the ozone layer. It is soluble in many organic solvents |
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Contaminant Sources | - Clean Air Act Chemicals
- EAFUS Chemicals
- FooDB Chemicals
- HPV EPA Chemicals
- STOFF IDENT Compounds
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Contaminant Type | Not Available |
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Chemical Structure | |
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Synonyms | Value | Source |
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Algofrene type 2 | HMDB | Arcton 12 | HMDB | Arcton 6 | HMDB | CCL2f2 | HMDB | CF2CL2 | HMDB | CFC 12 | HMDB | Chlorofluorocarbon 12 | HMDB | Chlorofluoromethane (CCL2f2) | HMDB | Dichloro(difluoro)methane | HMDB | Dichlorodifluoro-methane | HMDB | Dichlorodifluoromethane (NF) | HMDB | Diclorodifluometano | HMDB | Difluorodichloromethane | HMDB | Dwuchlorodwufluorometan | HMDB | Dymel 12 | HMDB | Electro-CF 12 | HMDB | Eskimon 12 | HMDB | Forane 12 | HMDB | Freon 12 | HMDB | Freon F-12 | HMDB | Freon-12 | HMDB | Frigen 12 | HMDB | Fron 12 | HMDB | Genetron 12 | HMDB | Halocarbon 12 | HMDB | Halon | HMDB | Halon 122 | HMDB | Isceon 122 | HMDB | Isot ron 2 | HMDB | Isotron 12 | HMDB | Isotron 2 | HMDB | Kaiser chemicals 12 | HMDB | Ledon 12 | HMDB | Propellant 12 | HMDB | Propellent 12 | HMDB | R 12 (Refrigerant) | HMDB | R 12, Refrigerant | HMDB | R12 | HMDB | Refrigerant 12 | HMDB | Refrigerant R 12 | HMDB | Refrigerant R12 | HMDB | Sterethox | HMDB | Ucon 12 | HMDB | Ucon 12/halocarbon 12 | HMDB | Freon 12, 18F-labeled | HMDB | Fluorocarbon-12 | HMDB | Cryosthesia -60C | HMDB | FC 12 | HMDB |
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Chemical Formula | CCl2F2 |
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Average Molecular Mass | 120.914 g/mol |
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Monoisotopic Mass | 119.935 g/mol |
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CAS Registry Number | 75-71-8 |
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IUPAC Name | dichlorodifluoromethane |
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Traditional Name | dichlorodifluoromethane |
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SMILES | FC(F)(Cl)Cl |
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InChI Identifier | InChI=1S/CCl2F2/c2-1(3,4)5 |
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InChI Key | PXBRQCKWGAHEHS-UHFFFAOYSA-N |
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Chemical Taxonomy |
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Description | belongs to the class of organic compounds known as chlorofluorocarbons. These are alkyhalide compounds that are composed only of chlorine, fluorine, and carbon atoms. |
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Kingdom | Organic compounds |
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Super Class | Organohalogen compounds |
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Class | Alkyl halides |
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Sub Class | Alkyl chlorides |
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Direct Parent | Chlorofluorocarbons |
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Alternative Parents | |
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Substituents | - Chlorofluorocarbon
- Halomethane
- Hydrocarbon derivative
- Organofluoride
- Organochloride
- Alkyl fluoride
- Aliphatic acyclic compound
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Molecular Framework | Aliphatic acyclic compounds |
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External Descriptors | |
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Biological Properties |
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Status | Detected and Not Quantified |
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Origin | Not Available |
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Cellular Locations | Not Available |
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Biofluid Locations | Not Available |
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Tissue Locations | Not Available |
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Pathways | Not Available |
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Applications | Not Available |
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Biological Roles | Not Available |
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Chemical Roles | Not Available |
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Physical Properties |
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State | Not Available |
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Appearance | Not Available |
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Experimental Properties | Property | Value |
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Melting Point | Not Available | Boiling Point | Not Available | Solubility | Not Available |
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Predicted Properties | |
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Spectra |
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Spectra | Spectrum Type | Description | Splash Key | View |
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GC-MS | GC-MS Spectrum - EI-B (Non-derivatized) | splash10-000i-9000000000-7ce8490add18c2d34cdb | Spectrum | GC-MS | GC-MS Spectrum - EI-B (Non-derivatized) | splash10-000i-9000000000-7ce8490add18c2d34cdb | Spectrum | Predicted GC-MS | Predicted GC-MS Spectrum - GC-MS (Non-derivatized) - 70eV, Positive | splash10-0uyi-4900000000-d9ecb6e559e4ac0b92ca | Spectrum | Predicted GC-MS | Predicted GC-MS Spectrum - GC-MS (Non-derivatized) - 70eV, Positive | Not Available | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 10V, Positive | splash10-00di-0900000000-972f2b0f297391bee854 | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 20V, Positive | splash10-00di-0900000000-972f2b0f297391bee854 | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 40V, Positive | splash10-00di-0900000000-972f2b0f297391bee854 | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 10V, Negative | splash10-014i-0900000000-fa4c5d80e0cdc8095779 | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 20V, Negative | splash10-014i-0900000000-fa4c5d80e0cdc8095779 | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 40V, Negative | splash10-014i-0900000000-fa4c5d80e0cdc8095779 | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 10V, Positive | splash10-00di-0900000000-3ff685d239190ad982fd | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 20V, Positive | splash10-00di-0900000000-3ff685d239190ad982fd | Spectrum | Predicted LC-MS/MS | Predicted LC-MS/MS Spectrum - 40V, Positive | splash10-00e9-5900000000-10d0e3114ac34d0ab8fa | Spectrum |
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Toxicity Profile |
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Route of Exposure | Not Available |
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Mechanism of Toxicity | Not Available |
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Metabolism | Not Available |
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Toxicity Values | Not Available |
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Lethal Dose | Not Available |
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Carcinogenicity (IARC Classification) | Not Available |
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Uses/Sources | Not Available |
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Minimum Risk Level | Not Available |
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Health Effects | Not Available |
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Symptoms | Not Available |
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Treatment | Not Available |
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Concentrations |
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| Not Available |
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External Links |
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DrugBank ID | Not Available |
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HMDB ID | HMDB0029570 |
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FooDB ID | FDB000725 |
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Phenol Explorer ID | Not Available |
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KNApSAcK ID | Not Available |
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BiGG ID | Not Available |
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BioCyc ID | Not Available |
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METLIN ID | Not Available |
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PDB ID | Not Available |
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Wikipedia Link | Dichlorodifluoromethane |
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Chemspider ID | 6151 |
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ChEBI ID | 52073 |
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PubChem Compound ID | 6391 |
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Kegg Compound ID | Not Available |
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YMDB ID | Not Available |
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ECMDB ID | Not Available |
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References |
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Synthesis Reference | Not Available |
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MSDS | Not Available |
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General References | 1. Graupner K, Haughey SA, Field TA, Mayhew CA, Hoffmann TH, May O, Fedor J, Allan M, Fabrikant II, Illenberger E, Braun M, Ruf MW, Hotop H: Low-energy electron attachment to the dichlorodifluoromethane (CCl2F2) molecule. J Phys Chem A. 2010 Jan 28;114(3):1474-84. doi: 10.1021/jp9081992. | 2. Schrikker AC, Wesenhagen H, Luijendijk SC: Intrapulmonary gas mixing and dead space in artificially ventilated dogs. Pflugers Arch. 1995 Sep;430(5):862-70. | 3. Rybolt TR, Bivona KT, Thomas HE, O'Dell CM: Comparison of gas-solid chromatography and MM2 force field molecular binding energies for greenhouse gases on a carbonaceous surface. J Colloid Interface Sci. 2009 Oct 1;338(1):287-92. doi: 10.1016/j.jcis.2009.06.001. Epub 2009 Jun 6. | 4. Tsai TR, Rose RA, Weidmann D, Wysocki G: Atmospheric vertical profiles of O3, N2O, CH4, CCl2F2, and H2O retrieved from external-cavity quantum-cascade laser heterodyne radiometer measurements. Appl Opt. 2012 Dec 20;51(36):8779-92. doi: 10.1364/AO.51.008779. | 5. Schrikker AC, Wesenhagen H, Luijendijk SC: Intrapulmonary gas mixing and pulmonary gas exchange in artificially ventilated dogs. Pflugers Arch. 1993 Oct;425(1-2):16-21. | 6. Gallegos P, Lutz J, Markwiese J, Ryti R, Mirenda R: Wildlife ecological screening levels for inhalation of volatile organic chemicals. Environ Toxicol Chem. 2007 Jun;26(6):1299-303. | 7. Anderson BJ, Bazant MZ, Tester JW, Trout BL: Application of the cell potential method to predict phase equilibria of multicomponent gas hydrate systems. J Phys Chem B. 2005 Apr 28;109(16):8153-63. | 8. Paulet G, Lessard Y: [The effect of difluorodichloromethane (FC 12) on isolated rat and rabbit heart]. C R Seances Soc Biol Fil. 1975;169(4):1048-53. | 9. Rodriguez C, Linge K, Blair P, Busetti F, Devine B, Van Buynder P, Weinstein P, Cook A: Recycled water: potential health risks from volatile organic compounds and use of 1,4-dichlorobenzene as treatment performance indicator. Water Res. 2012 Jan 1;46(1):93-106. doi: 10.1016/j.watres.2011.10.032. Epub 2011 Oct 25. | 10. Tamai T, Inazu K, Aika K: Dichlorodifluoromethane decomposition to CO2 with simultaneous halogen fixation by calcium oxide based materials. Environ Sci Technol. 2006 Feb 1;40(3):823-9. | 11. Weidmann D, Tsai T, Macleod NA, Wysocki G: Atmospheric observations of multiple molecular species using ultra-high-resolution external cavity quantum cascade laser heterodyne radiometry. Opt Lett. 2011 Jun 1;36(11):1951-3. doi: 10.1364/OL.36.001951. | 12. Fabrizi G, Fioretti M, Rocca LM: Occupational exposure to complex mixtures of volatile organic compounds in ambient air: desorption from activated charcoal using accelerated solvent extraction can replace carbon disulfide? Anal Bioanal Chem. 2013 Jan;405(2-3):961-76. doi: 10.1007/s00216-012-6379-7. Epub 2012 Sep 12. | 13. Authors unspecified: Community air quality guides. Dichlorodifluoromethane. (Difluorodichloromethane, Fluorocarbon No. 12). CCl-2F2. Am Ind Hyg Assoc J. 1968 Sep-Oct;29(5):513-6. | 14. Sun H, Chen L, Yue Z, Sun G, Ma W: [Measurement of chlorodifluoromethane(HCFC-22) in the atmosphere by using an O2-induced electron capture detector (ECD)]. Huan Jing Ke Xue. 2001 Jul;22(4):21-4. | 15. Shan X, Chen XJ, Zhou LX, Li ZJ, Liu T, Xue XX, Xu KZ: High resolution electron momentum spectroscopy of dichlorodifluoromethane: unambiguous assignments of outer valence molecular orbitals. J Chem Phys. 2006 Oct 21;125(15):154307. | 16. Durakovic Z, Stilinovic L, Bakran I Jr: Electrocardiographic changes in rats after inhalation of dichlorotetrafluoroethane, Arcton 114, C2Cl2F4. Jpn Heart J. 1976 Nov;17(6):753-9. | 17. Yannai, Shmuel. (2004) Dictionary of food compounds with CD-ROM: Additives, flavors, and ingredients. Boca Raton: Chapman & Hall/CRC. |
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