352752 <common-name>2-[(8r)-8-(3,5-difluorophenyl)-8-methyl-6-(111c)methyl-10-oxo-6,9-diazaspiro[4.5]decan-9-yl]-n-[(2s)-2'-oxospiro[1,3-dihydroindene-2,3'-1h-pyrrolo[2,3-b]pyridine]-5-yl]acetamide</common-name> <description>2-[(8r)-8-(3,5-difluorophenyl)-8-methyl-6-(111c)methyl-10-oxo-6,9-diazaspiro[4.5]decan-9-yl]-n-[(2s)-2'-oxospiro[1,3-dihydroindene-2,3'-1h-pyrrolo[2,3-b]pyridine]-5-yl]acetamide has the chemical formula C33H33F2N5O3. With an average molecular weight of 584.60 g/mol, 2-[(8r)-8-(3,5-difluorophenyl)-8-methyl-6-(111c)methyl-10-oxo-6,9-diazaspiro[4.5]decan-9-yl]-n-[(2s)-2'-oxospiro[1,3-dihydroindene-2,3'-1h-pyrrolo[2,3-b]pyridine]-5-yl]acetamide is a heavy molecule.</description> <cas>1263291-50-4</cas> <pubchem-id>155907712</pubchem-id> <chemical-formula>C33H33F2N5O3</chemical-formula> <weight>584.6</weight> <appearance nil="true"/> <melting-point nil="true"/> <boiling-point nil="true"/> <density nil="true"/> <solubility nil="true"/> <specific-gravity nil="true"/> <flash-point nil="true"/> <vapour-pressure nil="true"/> <route-of-exposure nil="true"/> <target nil="true"/> <mechanism-of-toxicity nil="true"/> <metabolism nil="true"/> <toxicity nil="true"/> <lethaldose nil="true"/> <carcinogenicity nil="true"/> <use-source nil="true"/> <min-risk-level nil="true"/> <health-effects nil="true"/> <symptoms nil="true"/> <treatment nil="true"/> <created-at type="dateTime">2026-08-31T19:14:50Z</created-at> <updated-at type="dateTime">2026-08-31T19:14:50Z</updated-at> <interacting-proteins nil="true"/> <wikipedia nil="true"/> <uniprot-id nil="true"/> <kegg-compound-id nil="true"/> <omim-id nil="true"/> <chebi-id nil="true"/> <biocyc-id nil="true"/> <ctd-id nil="true"/> <stitch-id nil="true"/> <drugbank-id nil="true"/> <pdb-id nil="true"/> <actor-id nil="true"/> <organism nil="true"/> <export type="boolean">true</export> <metabolizing-proteins nil="true"/> <transporting-proteins nil="true"/> <moldb-smiles>CC1(CN(C2(CCCC2)C(=O)N1CC(=O)NC3=CC4=C(CC5(C4)C6=C(NC5=O)N=CC=C6)C=C3)C)C7=CC(=CC(=C7)F)F</moldb-smiles> <moldb-formula>C33H33F2N5O3</moldb-formula> <moldb-inchi>InChI=1S/C33H33F2N5O3/c1-31(22-13-23(34)15-24(35)14-22)19-39(2)33(9-3-4-10-33)30(43)40(31)18-27(41)37-25-8-7-20-16-32(17-21(20)12-25)26-6-5-11-36-28(26)38-29(32)42/h5-8,11-15H,3-4,9-10,16-19H2,1-2H3,(H,37,41)(H,36,38,42)/t31-,32-/m0/s1/i2-1</moldb-inchi> <moldb-inchikey>WYWHBLFVASSGIJ-YUUWNJLSSA-N</moldb-inchikey> <moldb-average-mass type="decimal" nil="true"/> <moldb-mono-mass type="decimal">584.2665789</moldb-mono-mass> <origin nil="true"/> <state nil="true"/> <logp>3.4</logp> <hmdb-id nil="true"/> <chembl-id nil="true"/> <chemspider-id nil="true"/> <structure-image-file-name nil="true"/> <structure-image-content-type nil="true"/> <structure-image-file-size type="integer" nil="true"/> <structure-image-updated-at type="dateTime" nil="true"/> <biodb-id nil="true"/> <synthesis-reference nil="true"/> <structure-image-caption nil="true"/> <chemdb-id>CHEM348645</chemdb-id> <dsstox-id nil="true"/> <toxcast-id nil="true"/> <stoff-ident-origin nil="true"/> <stoff-ident-id nil="true"/> <susdat-id nil="true"/> <iupac>2-[(8r)-8-(3,5-difluorophenyl)-8-methyl-6-(111c)methyl-10-oxo-6,9-diazaspiro[4.5]decan-9-yl]-n-[(2s)-2'-oxospiro[1,3-dihydroindene-2,3'-1h-pyrrolo[2,3-b]pyridine]-5-yl]acetamide</iupac> <moldb-polar-surface-area nil="true"/> <moldb-refractivity nil="true"/> <moldb-polarizability nil="true"/> <moldb-rotatable-bond-count nil="true"/> <moldb-acceptor-count nil="true"/> <moldb-donor-count nil="true"/> <moldb-pka-strongest-acidic nil="true"/> <moldb-pka-strongest-basic nil="true"/> <moldb-physiological-charge nil="true"/> <moldb-number-of-rings nil="true"/> <moldb-alogps-logp nil="true"/> <moldb-alogps-logs nil="true"/> <moldb-alogps-solubility nil="true"/> <kingdom nil="true"/> <superklass nil="true"/> <klass nil="true"/> <subklass nil="true"/> <paper-count type="integer" nil="true"/> <sync-id>CED0303036</sync-id> <structure-inchikey>WYWHBLFVASSGIJ-UHFFFAOYSA-N</structure-inchikey> <structure-fingerprint>40000000008000000000000000000000400081000000000000000100000000020000200000000400000020000800000020000080000000002000000000000000080000800000200000000000200000000000100040000000000001000000320102000000100002001000000400000201080000000000000000000008001000480000008100002000000040c0200000000080000000080000000020080000008200000040000000080000080000000010080800001000000200000008000040000000000000000002000000020000080000000000000200000000000000008000000000002040000000000400800000000000080000000000000105</structure-fingerprint> <structure-pattern-fingerprint>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</structure-pattern-fingerprint> <structure-pickle type="binary" encoding="base64">776t3gAAAAAQAAAAAwAAAAAAAAArAAAAMQAAAIABBgBgAAAAAQMGACAAAAAE BgBgAAAAAgIHACAAAAADBgAgAAAABAYAYAAAAAICBgBgAAAAAgIGAGAAAAAC AgYAYAAAAAICBgAoAAAAAwQIACgAAAADAgcAKAAAAAMDBgBgAAAAAgIGACgA AAADBAgAKAAAAAMCBwBoAAAAAwIBBkAoAAAAAwQGQGgAAAADAwEGQCgAAAAD BAZAKAAAAAMEBgBgAAAAAgIGACAAAAAEBgBgAAAAAgIGQCgAAAADBAZAKAAA AAMEBwBoAAAAAwIBBgAoAAAAAwQIACgAAAADAgdAKAAAAAMDBkBoAAAAAwMB BkBoAAAAAwMBBkBoAAAAAwMBBkBoAAAAAwMBBkBoAAAAAwMBBgBgAAAAAQMG QCgAAAADBAZAaAAAAAMDAQZAKAAAAAMEBkBoAAAAAwMBBkAoAAAAAwQGQGgA AAADAwEJACAAAAABCQAgAAAAAQsAAQABAgACAwADBAAEBQAFBgAGBwAHCAAE CQAJCigCCQsgCwwADA0ADQ4oAg0PIA8QIBARaAwREmgMEhNoDBMUABQVABUW ABUXABcYaAwYGSAZGiAaGygCGBxoDBwdaAwdHmgMHh9oDBMgaAwgIWgMAyIA ASMAIyRoDCQlaAwlJmgMJidoDCcoaAwnKQAlKgALAQAIBAAhEGgMFhIAGhUA HxdoDCgjaAxCBwAAAAYCAwQJCwEFBQQIBwYGERITICEQBRQTEhYVBRkYFxUa BhwdHh8XGAYkJSYnKCMXBAAAAAAAAAAW </structure-pickle> <structure-indexed-at type="dateTime">2026-09-19T05:50:27Z</structure-indexed-at> </compound>