346391 <common-name>(2r)-2-[(1s)-6,7-dihydroxy-1-[2-[4-(trifluoromethyl)phenyl]ethyl]-3,4-dihydro-1h-isoquinolin-2-yl]-n-methyl-2-phenylacetamide</common-name> <description>(2r)-2-[(1s)-6,7-dihydroxy-1-[2-[4-(trifluoromethyl)phenyl]ethyl]-3,4-dihydro-1h-isoquinolin-2-yl]-n-methyl-2-phenylacetamide is a chemical compound with the formula C27H27F3N2O3. It has an average molecular weight of 484.50 g/mol.</description> <cas nil="true"/> <pubchem-id>118753422</pubchem-id> <chemical-formula>C27H27F3N2O3</chemical-formula> <weight>484.5</weight> <appearance nil="true"/> <melting-point nil="true"/> <boiling-point nil="true"/> <density nil="true"/> <solubility nil="true"/> <specific-gravity nil="true"/> <flash-point nil="true"/> <vapour-pressure nil="true"/> <route-of-exposure nil="true"/> <target nil="true"/> <mechanism-of-toxicity nil="true"/> <metabolism nil="true"/> <toxicity nil="true"/> <lethaldose nil="true"/> <carcinogenicity nil="true"/> <use-source nil="true"/> <min-risk-level nil="true"/> <health-effects nil="true"/> <symptoms nil="true"/> <treatment nil="true"/> <created-at type="dateTime">2026-08-31T09:49:01Z</created-at> <updated-at type="dateTime">2026-08-31T09:49:01Z</updated-at> <interacting-proteins nil="true"/> <wikipedia nil="true"/> <uniprot-id nil="true"/> <kegg-compound-id nil="true"/> <omim-id nil="true"/> <chebi-id nil="true"/> <biocyc-id nil="true"/> <ctd-id nil="true"/> <stitch-id nil="true"/> <drugbank-id nil="true"/> <pdb-id nil="true"/> <actor-id nil="true"/> <organism nil="true"/> <export type="boolean">true</export> <metabolizing-proteins nil="true"/> <transporting-proteins nil="true"/> <moldb-smiles>CNC(=O)C(C1=CC=CC=C1)N2CCC3=CC(=C(C=C3C2CCC4=CC=C(C=C4)C(F)(F)F)O)O</moldb-smiles> <moldb-formula>C27H27F3N2O3</moldb-formula> <moldb-inchi>InChI=1S/C27H27F3N2O3/c1-31-26(35)25(18-5-3-2-4-6-18)32-14-13-19-15-23(33)24(34)16-21(19)22(32)12-9-17-7-10-20(11-8-17)27(28,29)30/h2-8,10-11,15-16,22,25,33-34H,9,12-14H2,1H3,(H,31,35)/t22-,25+/m0/s1</moldb-inchi> <moldb-inchikey>CKPMZERRTCMUKQ-WIOPSUGQSA-N</moldb-inchikey> <moldb-average-mass type="decimal" nil="true"/> <moldb-mono-mass type="decimal">484.1973772</moldb-mono-mass> <origin nil="true"/> <state nil="true"/> <logp>5.4</logp> <hmdb-id nil="true"/> <chembl-id nil="true"/> <chemspider-id nil="true"/> <structure-image-file-name nil="true"/> <structure-image-content-type nil="true"/> <structure-image-file-size type="integer" nil="true"/> <structure-image-updated-at type="dateTime" nil="true"/> <biodb-id nil="true"/> <synthesis-reference nil="true"/> <structure-image-caption nil="true"/> <chemdb-id>CHEM342284</chemdb-id> <dsstox-id nil="true"/> <toxcast-id nil="true"/> <stoff-ident-origin nil="true"/> <stoff-ident-id nil="true"/> <susdat-id nil="true"/> <iupac>(2r)-2-[(1s)-6,7-dihydroxy-1-[2-[4-(trifluoromethyl)phenyl]ethyl]-3,4-dihydro-1h-isoquinolin-2-yl]-n-methyl-2-phenylacetamide</iupac> <moldb-polar-surface-area nil="true"/> <moldb-refractivity nil="true"/> <moldb-polarizability nil="true"/> <moldb-rotatable-bond-count nil="true"/> <moldb-acceptor-count nil="true"/> <moldb-donor-count nil="true"/> <moldb-pka-strongest-acidic nil="true"/> <moldb-pka-strongest-basic nil="true"/> <moldb-physiological-charge nil="true"/> <moldb-number-of-rings nil="true"/> <moldb-alogps-logp nil="true"/> <moldb-alogps-logs nil="true"/> <moldb-alogps-solubility nil="true"/> <kingdom>Organic compounds</kingdom> <superklass>Organoheterocyclic compounds</superklass> <klass>Isoquinolines and derivatives</klass> <subklass>Benzylisoquinolines</subklass> <paper-count type="integer" nil="true"/> <sync-id>CED0296744</sync-id> <structure-inchikey>CKPMZERRTCMUKQ-UHFFFAOYSA-N</structure-inchikey> <structure-fingerprint>40000000000000000000800000002000000000000000000100000000000000000000000000000200000000400000000104000000000000000000000000000000000000000001000400040000000000000020000000000000000000014000000000000000014000008000000000100000000000020100000200000000000000101000049040000000800000020000000080000000000100000001081000080000000000000020000000000400080010000040020000040000008000000000000000000000000400002100000000000008400000000000440001200220000040000000000000000000000040008000000400800000000000000000000000000000</structure-fingerprint> 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