344166 <common-name>2-[[(2s)-1-[5-(4-fluorophenyl)-2-methyl-1,3-thiazole-4-carbonyl]piperidin-2-yl]methyl]-5-hydroxyisoquinolin-1-one</common-name> <description>2-[[(2s)-1-[5-(4-fluorophenyl)-2-methyl-1,3-thiazole-4-carbonyl]piperidin-2-yl]methyl]-5-hydroxyisoquinolin-1-one is a chemical compound with the formula C26H24FN3O3S. It has an average molecular weight of 477.60 g/mol.</description> <cas nil="true"/> <pubchem-id>118753162</pubchem-id> <chemical-formula>C26H24FN3O3S</chemical-formula> <weight>477.6</weight> <appearance nil="true"/> <melting-point nil="true"/> <boiling-point nil="true"/> <density nil="true"/> <solubility nil="true"/> <specific-gravity nil="true"/> <flash-point nil="true"/> <vapour-pressure nil="true"/> <route-of-exposure nil="true"/> <target nil="true"/> <mechanism-of-toxicity nil="true"/> <metabolism nil="true"/> <toxicity nil="true"/> <lethaldose nil="true"/> <carcinogenicity nil="true"/> <use-source nil="true"/> <min-risk-level nil="true"/> <health-effects nil="true"/> <symptoms nil="true"/> <treatment nil="true"/> <created-at type="dateTime">2026-08-31T06:00:23Z</created-at> <updated-at type="dateTime">2026-08-31T06:00:23Z</updated-at> <interacting-proteins nil="true"/> <wikipedia nil="true"/> <uniprot-id nil="true"/> <kegg-compound-id nil="true"/> <omim-id nil="true"/> <chebi-id nil="true"/> <biocyc-id nil="true"/> <ctd-id nil="true"/> <stitch-id nil="true"/> <drugbank-id nil="true"/> <pdb-id nil="true"/> <actor-id nil="true"/> <organism nil="true"/> <export type="boolean">true</export> <metabolizing-proteins nil="true"/> <transporting-proteins nil="true"/> <moldb-smiles>CC1=NC(=C(S1)C2=CC=C(C=C2)F)C(=O)N3CCCCC3CN4C=CC5=C(C4=O)C=CC=C5O</moldb-smiles> <moldb-formula>C26H24FN3O3S</moldb-formula> <moldb-inchi>InChI=1S/C26H24FN3O3S/c1-16-28-23(24(34-16)17-8-10-18(27)11-9-17)26(33)30-13-3-2-5-19(30)15-29-14-12-20-21(25(29)32)6-4-7-22(20)31/h4,6-12,14,19,31H,2-3,5,13,15H2,1H3/t19-/m0/s1</moldb-inchi> <moldb-inchikey>GKLCFHOWTGKAFS-IBGZPJMESA-N</moldb-inchikey> <moldb-average-mass type="decimal" nil="true"/> <moldb-mono-mass type="decimal">477.152241</moldb-mono-mass> <origin nil="true"/> <state nil="true"/> <logp>4.8</logp> <hmdb-id nil="true"/> <chembl-id nil="true"/> <chemspider-id nil="true"/> <structure-image-file-name nil="true"/> <structure-image-content-type nil="true"/> <structure-image-file-size type="integer" nil="true"/> <structure-image-updated-at type="dateTime" nil="true"/> <biodb-id nil="true"/> <synthesis-reference nil="true"/> <structure-image-caption nil="true"/> <chemdb-id>CHEM340059</chemdb-id> <dsstox-id nil="true"/> <toxcast-id nil="true"/> <stoff-ident-origin nil="true"/> <stoff-ident-id nil="true"/> <susdat-id nil="true"/> <iupac>2-[[(2s)-1-[5-(4-fluorophenyl)-2-methyl-1,3-thiazole-4-carbonyl]piperidin-2-yl]methyl]-5-hydroxyisoquinolin-1-one</iupac> <moldb-polar-surface-area nil="true"/> <moldb-refractivity nil="true"/> <moldb-polarizability nil="true"/> <moldb-rotatable-bond-count nil="true"/> <moldb-acceptor-count nil="true"/> <moldb-donor-count nil="true"/> <moldb-pka-strongest-acidic nil="true"/> <moldb-pka-strongest-basic nil="true"/> <moldb-physiological-charge nil="true"/> <moldb-number-of-rings nil="true"/> <moldb-alogps-logp nil="true"/> <moldb-alogps-logs nil="true"/> <moldb-alogps-solubility nil="true"/> <kingdom>Organic compounds</kingdom> <superklass>Organoheterocyclic compounds</superklass> <klass>Isoquinolines and derivatives</klass> <subklass>Isoquinolones and derivatives</subklass> <paper-count type="integer" nil="true"/> <sync-id>CED0294538</sync-id> <structure-inchikey>GKLCFHOWTGKAFS-UHFFFAOYSA-N</structure-inchikey> <structure-fingerprint>802000000000000000002000000040000000000020010000000000000020000020000000002000000000000200000000000000200080000000011000000000000000000000000020004010000010000000000000000000000000010000000010000000080020800800020100000000000000000000100801000040000000800400200000000000800000000000000000000000010000000000020016000000040100080000002000000200010000008000008000400000008000040000402100000000000000020100000000002000000200000010000000000001000001000040000000000400800000000000000002000000000000</structure-fingerprint> <structure-pattern-fingerprint>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</structure-pattern-fingerprint> <structure-pickle>ï¾­Þ����������������"���&���€���`������@(������@(������@(������@(������@(������@(������@h�������@h�������@(������@h�������@h������ � ������(�������(�������(�������`�������`�������`�������`�������`�������`������@(������@h�������@h�������@(������@(������@(�������(������@h�������@h�������@h�������@(�������h������������h���h���h���h��� ��h���h�� h� h� �h� ��� �(� � �����������������������h���h���h���h���h���(���h���h���h�� h� ! ��h���h������h� �h�B������������� �������������������� ������������</structure-pickle> <structure-indexed-at type="dateTime">2026-09-19T05:43:27Z</structure-indexed-at> </compound>