332543 <common-name>N-[(1r,5s)-8-[(4-chlorophenyl)methyl]-8-azabicyclo[3.2.1]octan-3-yl]-2-(dimethylamino)-4-methoxypyrimidine-5-carboxamide</common-name> <description>N-[(1r,5s)-8-[(4-chlorophenyl)methyl]-8-azabicyclo[3.2.1]octan-3-yl]-2-(dimethylamino)-4-methoxypyrimidine-5-carboxamide is a chemical compound with the formula C22H28ClN5O2. It has an average molecular weight of 429.90 g/mol.</description> <cas nil="true"/> <pubchem-id>13382869</pubchem-id> <chemical-formula>C22H28ClN5O2</chemical-formula> <weight>429.9</weight> <appearance nil="true"/> <melting-point nil="true"/> <boiling-point nil="true"/> <density nil="true"/> <solubility nil="true"/> <specific-gravity nil="true"/> <flash-point nil="true"/> <vapour-pressure nil="true"/> <route-of-exposure nil="true"/> <target nil="true"/> <mechanism-of-toxicity nil="true"/> <metabolism nil="true"/> <toxicity nil="true"/> <lethaldose nil="true"/> <carcinogenicity nil="true"/> <use-source nil="true"/> <min-risk-level nil="true"/> <health-effects nil="true"/> <symptoms nil="true"/> <treatment nil="true"/> <created-at type="dateTime">2026-08-30T13:44:23Z</created-at> <updated-at type="dateTime">2026-08-30T13:44:23Z</updated-at> <interacting-proteins nil="true"/> <wikipedia nil="true"/> <uniprot-id nil="true"/> <kegg-compound-id nil="true"/> <omim-id nil="true"/> <chebi-id nil="true"/> <biocyc-id nil="true"/> <ctd-id nil="true"/> <stitch-id nil="true"/> <drugbank-id nil="true"/> <pdb-id nil="true"/> <actor-id nil="true"/> <organism nil="true"/> <export type="boolean">true</export> <metabolizing-proteins nil="true"/> <transporting-proteins nil="true"/> <moldb-smiles>CN(C)C1=NC=C(C(=N1)OC)C(=O)NC2CC3CCC(C2)N3CC4=CC=C(C=C4)Cl</moldb-smiles> <moldb-formula>C22H28ClN5O2</moldb-formula> <moldb-inchi>InChI=1S/C22H28ClN5O2/c1-27(2)22-24-12-19(21(26-22)30-3)20(29)25-16-10-17-8-9-18(11-16)28(17)13-14-4-6-15(23)7-5-14/h4-7,12,16-18H,8-11,13H2,1-3H3,(H,25,29)/t16?,17-,18+</moldb-inchi> <moldb-inchikey>GEJOURLVTDCMJS-AYHJJNSGSA-N</moldb-inchikey> <moldb-average-mass type="decimal" nil="true"/> <moldb-mono-mass type="decimal">429.1931528</moldb-mono-mass> <origin nil="true"/> <state nil="true"/> <logp>3.6</logp> <hmdb-id nil="true"/> <chembl-id nil="true"/> <chemspider-id nil="true"/> <structure-image-file-name nil="true"/> <structure-image-content-type nil="true"/> <structure-image-file-size type="integer" nil="true"/> <structure-image-updated-at type="dateTime" nil="true"/> <biodb-id nil="true"/> <synthesis-reference nil="true"/> <structure-image-caption nil="true"/> <chemdb-id>CHEM328436</chemdb-id> <dsstox-id nil="true"/> <toxcast-id nil="true"/> <stoff-ident-origin nil="true"/> <stoff-ident-id nil="true"/> <susdat-id nil="true"/> <iupac>N-[(1r,5s)-8-[(4-chlorophenyl)methyl]-8-azabicyclo[3.2.1]octan-3-yl]-2-(dimethylamino)-4-methoxypyrimidine-5-carboxamide</iupac> <moldb-polar-surface-area nil="true"/> <moldb-refractivity nil="true"/> <moldb-polarizability nil="true"/> <moldb-rotatable-bond-count nil="true"/> <moldb-acceptor-count nil="true"/> <moldb-donor-count nil="true"/> <moldb-pka-strongest-acidic nil="true"/> <moldb-pka-strongest-basic nil="true"/> <moldb-physiological-charge nil="true"/> <moldb-number-of-rings nil="true"/> <moldb-alogps-logp nil="true"/> <moldb-alogps-logs nil="true"/> <moldb-alogps-solubility nil="true"/> <kingdom>Organic compounds</kingdom> <superklass>Organoheterocyclic compounds</superklass> <klass>Piperidines</klass> <subklass>Benzylpiperidines</subklass> <paper-count type="integer" nil="true"/> <sync-id>CED0283054</sync-id> <structure-inchikey>GEJOURLVTDCMJS-UHFFFAOYSA-N</structure-inchikey> <structure-fingerprint>1000000000000000800000000000002000000000000000000080000000000000800000000200000020000000002018004000000000000000000002000000000000000000400000000000000000000020001000002100000000000000000000000000110080400040000200004000000000020100000000000000000000100000000040020001020000000000000080100000000000000000000000000000000800040004000000000000080000000002000000080000000000000000000180000000000004000000000020000000000010000800000000000220040000000000000000002001000040000000020410000000000000000100000000000040</structure-fingerprint> <structure-pattern-fingerprint>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</structure-pattern-fingerprint> <structure-pickle>ï¾­Þ��������������������!���€���`�������(�������`������@(������@(������@h�������@(������@(������@(�������(�������`�������(�������(�������h��������`�������`�������`�������`�������`�������`�������`������� ������`������@(������@h�������@h�������@(������@h�������@h�������� ������������� ��h���h���h���h���h�� ��� ��(�� �������������������������������h���h���h���h���h������h���������h�B�����������������������������������������</structure-pickle> <structure-indexed-at type="dateTime">2026-09-19T05:34:48Z</structure-indexed-at> </compound>