331017 <common-name>[4-hydroxy-4-[3-(trifluoromethyl)phenyl]piperidin-1-yl]-[(1r,2r)-2-phenylcyclopropyl]methanone</common-name> <description>[4-hydroxy-4-[3-(trifluoromethyl)phenyl]piperidin-1-yl]-[(1r,2r)-2-phenylcyclopropyl]methanone is a chemical compound with the formula C22H22F3NO2. It has an average molecular weight of 389.40 g/mol.</description> <cas>102071-61-4</cas> <pubchem-id>3064351</pubchem-id> <chemical-formula>C22H22F3NO2</chemical-formula> <weight>389.4</weight> <appearance nil="true"/> <melting-point nil="true"/> <boiling-point nil="true"/> <density nil="true"/> <solubility nil="true"/> <specific-gravity nil="true"/> <flash-point nil="true"/> <vapour-pressure nil="true"/> <route-of-exposure nil="true"/> <target nil="true"/> <mechanism-of-toxicity nil="true"/> <metabolism nil="true"/> <toxicity nil="true"/> <lethaldose nil="true"/> <carcinogenicity nil="true"/> <use-source nil="true"/> <min-risk-level nil="true"/> <health-effects nil="true"/> <symptoms nil="true"/> <treatment nil="true"/> <created-at type="dateTime">2026-08-30T11:43:52Z</created-at> <updated-at type="dateTime">2026-08-30T11:43:52Z</updated-at> <interacting-proteins nil="true"/> <wikipedia nil="true"/> <uniprot-id nil="true"/> <kegg-compound-id nil="true"/> <omim-id nil="true"/> <chebi-id nil="true"/> <biocyc-id nil="true"/> <ctd-id nil="true"/> <stitch-id nil="true"/> <drugbank-id nil="true"/> <pdb-id nil="true"/> <actor-id nil="true"/> <organism nil="true"/> <export type="boolean">true</export> <metabolizing-proteins nil="true"/> <transporting-proteins nil="true"/> <moldb-smiles>C1CN(CCC1(C2=CC(=CC=C2)C(F)(F)F)O)C(=O)C3CC3C4=CC=CC=C4</moldb-smiles> <moldb-formula>C22H22F3NO2</moldb-formula> <moldb-inchi>InChI=1S/C22H22F3NO2/c23-22(24,25)17-8-4-7-16(13-17)21(28)9-11-26(12-10-21)20(27)19-14-18(19)15-5-2-1-3-6-15/h1-8,13,18-19,28H,9-12,14H2/t18-,19+/m0/s1</moldb-inchi> <moldb-inchikey>HDOBMLLBKGSHNB-RBUKOAKNSA-N</moldb-inchikey> <moldb-average-mass type="decimal" nil="true"/> <moldb-mono-mass type="decimal">389.1602634</moldb-mono-mass> <origin nil="true"/> <state nil="true"/> <logp>3.6</logp> <hmdb-id nil="true"/> <chembl-id nil="true"/> <chemspider-id nil="true"/> <structure-image-file-name nil="true"/> <structure-image-content-type nil="true"/> <structure-image-file-size type="integer" nil="true"/> <structure-image-updated-at type="dateTime" nil="true"/> <biodb-id nil="true"/> <synthesis-reference nil="true"/> <structure-image-caption nil="true"/> <chemdb-id>CHEM326910</chemdb-id> <dsstox-id nil="true"/> <toxcast-id nil="true"/> <stoff-ident-origin nil="true"/> <stoff-ident-id nil="true"/> <susdat-id nil="true"/> <iupac>[4-hydroxy-4-[3-(trifluoromethyl)phenyl]piperidin-1-yl]-[(1r,2r)-2-phenylcyclopropyl]methanone</iupac> <moldb-polar-surface-area nil="true"/> <moldb-refractivity nil="true"/> <moldb-polarizability nil="true"/> <moldb-rotatable-bond-count nil="true"/> <moldb-acceptor-count nil="true"/> <moldb-donor-count nil="true"/> <moldb-pka-strongest-acidic nil="true"/> <moldb-pka-strongest-basic nil="true"/> <moldb-physiological-charge nil="true"/> <moldb-number-of-rings nil="true"/> <moldb-alogps-logp nil="true"/> <moldb-alogps-logs nil="true"/> <moldb-alogps-solubility nil="true"/> <kingdom>Organic compounds</kingdom> <superklass>Organoheterocyclic compounds</superklass> <klass>Piperidines</klass> <subklass>Phenylpiperidines</subklass> <paper-count type="integer" nil="true"/> <sync-id>CED0281557</sync-id> <structure-inchikey>HDOBMLLBKGSHNB-UHFFFAOYSA-N</structure-inchikey> <structure-fingerprint>2000000000010000000000004000000002000000000000000000000000000000000004000080000000000100000000000000008000000008000000000000000000000020000000000000000000000001000008000000014000000000000000100000000000020100000000000000000000100001000008000000800008000000000028200000000100000000200000080001000880040000000000000000080000000040000000040000008000000000200100000000000000000000000000000001010000000000000000000200000000000000000000000000000040000000000400800000000000400000004040000000</structure-fingerprint> <structure-pattern-fingerprint>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</structure-pattern-fingerprint> <structure-pickle>ï¾­Þ������������������������€���`�������`�������(�������`�������`������� �����@(������@h�������@(������@h�������@h�������@h�������� ���� � ���� � ���� � ������`�������(�������(�������`�������`�������`������@(������@h�������@h�������@h�������@h�������@h���������������������������h���h�� h� h� �h����� ������������ ��(���������������h���h���h���h���h������h������h�B�������������� �����������������������</structure-pickle> <structure-indexed-at type="dateTime">2026-09-19T05:33:26Z</structure-indexed-at> </compound>