145781 <common-name>Anvumetostat</common-name> <description>Anvumetostat belongs to the morpholines, a subclass of oxazinanes within the organic compounds. This organoheterocyclic compound has the formula C22H19F3N4O3 and an average molecular weight of 444.41 g/mol.</description> <cas>2790567-82-5</cas> <pubchem-id nil="true"/> <chemical-formula>C22H19F3N4O3</chemical-formula> <weight nil="true"/> <appearance nil="true"/> <melting-point nil="true"/> <boiling-point nil="true"/> <density nil="true"/> <solubility nil="true"/> <specific-gravity nil="true"/> <flash-point nil="true"/> <vapour-pressure nil="true"/> <route-of-exposure nil="true"/> <target nil="true"/> <mechanism-of-toxicity nil="true"/> <metabolism nil="true"/> <toxicity nil="true"/> <lethaldose nil="true"/> <carcinogenicity nil="true"/> <use-source nil="true"/> <min-risk-level nil="true"/> <health-effects nil="true"/> <symptoms nil="true"/> <treatment nil="true"/> <created-at type="dateTime">2026-05-14T21:06:11Z</created-at> <updated-at type="dateTime">2026-05-14T21:06:11Z</updated-at> <interacting-proteins nil="true"/> <wikipedia nil="true"/> <uniprot-id nil="true"/> <kegg-compound-id nil="true"/> <omim-id nil="true"/> <chebi-id nil="true"/> <biocyc-id nil="true"/> <ctd-id nil="true"/> <stitch-id nil="true"/> <drugbank-id>DB32647</drugbank-id> <pdb-id nil="true"/> <actor-id nil="true"/> <organism nil="true"/> <export type="boolean">true</export> <metabolizing-proteins nil="true"/> <transporting-proteins nil="true"/> <moldb-smiles>NC1=C2COCC2=C2C=C(N=CC2=N1)C(=O)N1CCOC[C@@H]1C1=CC=C(C=C1)C(F)(F)F</moldb-smiles> <moldb-formula>C22H19F3N4O3</moldb-formula> <moldb-inchi>InChI=1S/C22H19F3N4O3/c23-22(24,25)13-3-1-12(2-4-13)19-11-31-6-5-29(19)21(30)17-7-14-15-9-32-10-16(15)20(26)28-18(14)8-27-17/h1-4,7-8,19H,5-6,9-11H2,(H2,26,28)/t19-/m0/s1</moldb-inchi> <moldb-inchikey>BFEBTMFPRJPBTK-LJQANCHMSA-N</moldb-inchikey> <moldb-average-mass type="decimal">444.414</moldb-average-mass> <moldb-mono-mass type="decimal">444.140924977</moldb-mono-mass> <origin nil="true"/> <state nil="true"/> <logp nil="true"/> <hmdb-id nil="true"/> <chembl-id nil="true"/> <chemspider-id nil="true"/> <structure-image-file-name nil="true"/> <structure-image-content-type nil="true"/> <structure-image-file-size type="integer" nil="true"/> <structure-image-updated-at type="dateTime" nil="true"/> <biodb-id nil="true"/> <synthesis-reference nil="true"/> <structure-image-caption nil="true"/> <chemdb-id>CHEM141674</chemdb-id> <dsstox-id nil="true"/> <toxcast-id nil="true"/> <stoff-ident-origin nil="true"/> <stoff-ident-id nil="true"/> <susdat-id nil="true"/> <iupac nil="true"/> <moldb-polar-surface-area nil="true"/> <moldb-refractivity nil="true"/> <moldb-polarizability nil="true"/> <moldb-rotatable-bond-count nil="true"/> <moldb-acceptor-count nil="true"/> <moldb-donor-count nil="true"/> <moldb-pka-strongest-acidic nil="true"/> <moldb-pka-strongest-basic nil="true"/> <moldb-physiological-charge nil="true"/> <moldb-number-of-rings nil="true"/> <moldb-alogps-logp nil="true"/> <moldb-alogps-logs nil="true"/> <moldb-alogps-solubility nil="true"/> <kingdom>Organic compounds</kingdom> <superklass>Organoheterocyclic compounds</superklass> <klass>Oxazinanes</klass> <subklass>Morpholines</subklass> <paper-count type="integer">0</paper-count> <sync-id>CED0126631</sync-id> <structure-inchikey>BFEBTMFPRJPBTK-LJQANCHMSA-N</structure-inchikey> <structure-fingerprint>80000000000a0000000000000000000000000000000200000000002002000000000000000400021000000000201008000000000000000100010400000000000000000004000000000208000000000000000000000000000008000000140000000000100001000080000000201000200000000000000001000800000000000001040000000000000000010000002000000040000000800010000000080000000000400004800000000400000400c5000008000008000000100000000000000000000000000000000400000000000000000000200000000008010000000000001000040000100000410800000000000000000000000000000</structure-fingerprint> 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