145684 <common-name>AZD1390</common-name> <description>AZD1390 belongs to the imidazoquinolines, a subclass of quinolines and derivatives within the organic compounds. It is an organoheterocyclic compound with the formula C27H32FN5O2 and an average molecular weight of 477.58 g/mol.</description> <cas>2089288-03-7</cas> <pubchem-id>126689157</pubchem-id> <chemical-formula>C27H32FN5O2</chemical-formula> <weight>477.6</weight> <appearance nil="true"/> <melting-point nil="true"/> <boiling-point nil="true"/> <density nil="true"/> <solubility nil="true"/> <specific-gravity nil="true"/> <flash-point nil="true"/> <vapour-pressure nil="true"/> <route-of-exposure nil="true"/> <target nil="true"/> <mechanism-of-toxicity nil="true"/> <metabolism nil="true"/> <toxicity nil="true"/> <lethaldose nil="true"/> <carcinogenicity nil="true"/> <use-source nil="true"/> <min-risk-level nil="true"/> <health-effects nil="true"/> <symptoms nil="true"/> <treatment nil="true"/> <created-at type="dateTime">2026-05-14T20:52:17Z</created-at> <updated-at type="dateTime">2026-08-22T07:30:57Z</updated-at> <interacting-proteins nil="true"/> <wikipedia nil="true"/> <uniprot-id nil="true"/> <kegg-compound-id nil="true"/> <omim-id nil="true"/> <chebi-id nil="true"/> <biocyc-id nil="true"/> <ctd-id nil="true"/> <stitch-id nil="true"/> <drugbank-id>DB23332</drugbank-id> <pdb-id nil="true"/> <actor-id nil="true"/> <organism nil="true"/> <export type="boolean">true</export> <metabolizing-proteins nil="true"/> <transporting-proteins nil="true"/> <moldb-smiles>CC(C)N1C(=O)N(C)C2=C1C1=C(C=C(F)C(=C1)C1=CC=C(OCCCN3CCCCC3)N=C1)N=C2</moldb-smiles> <moldb-formula>C27H32FN5O2</moldb-formula> <moldb-inchi>InChI=1S/C27H32FN5O2/c1-18(2)33-26-21-14-20(22(28)15-23(21)29-17-24(26)31(3)27(33)34)19-8-9-25(30-16-19)35-13-7-12-32-10-5-4-6-11-32/h8-9,14-18H,4-7,10-13H2,1-3H3</moldb-inchi> <moldb-inchikey>VQSZIPCGAGVRRP-UHFFFAOYSA-N</moldb-inchikey> <moldb-average-mass type="decimal">477.584</moldb-average-mass> <moldb-mono-mass type="decimal">477.254003453</moldb-mono-mass> <origin nil="true"/> <state nil="true"/> <logp>4.2</logp> <hmdb-id nil="true"/> <chembl-id nil="true"/> <chemspider-id nil="true"/> <structure-image-file-name nil="true"/> <structure-image-content-type nil="true"/> <structure-image-file-size type="integer" nil="true"/> <structure-image-updated-at type="dateTime" nil="true"/> <biodb-id nil="true"/> <synthesis-reference nil="true"/> <structure-image-caption nil="true"/> <chemdb-id>CHEM141577</chemdb-id> <dsstox-id nil="true"/> <toxcast-id nil="true"/> <stoff-ident-origin nil="true"/> <stoff-ident-id nil="true"/> <susdat-id nil="true"/> <iupac>7-fluoro-3-methyl-8-[6-(3-piperidin-1-ylpropoxy)-3-pyridinyl]-1-propan-2-ylimidazo[4,5-c]quinolin-2-one</iupac> <moldb-polar-surface-area nil="true"/> <moldb-refractivity nil="true"/> <moldb-polarizability nil="true"/> <moldb-rotatable-bond-count nil="true"/> <moldb-acceptor-count nil="true"/> <moldb-donor-count nil="true"/> <moldb-pka-strongest-acidic nil="true"/> <moldb-pka-strongest-basic nil="true"/> <moldb-physiological-charge nil="true"/> <moldb-number-of-rings nil="true"/> <moldb-alogps-logp nil="true"/> <moldb-alogps-logs nil="true"/> <moldb-alogps-solubility nil="true"/> <kingdom>Organic compounds</kingdom> <superklass>Organoheterocyclic compounds</superklass> <klass>Quinolines and derivatives</klass> <subklass>Imidazoquinolines</subklass> <paper-count type="integer">412</paper-count> <sync-id>CED0011926</sync-id> <structure-inchikey>VQSZIPCGAGVRRP-UHFFFAOYSA-N</structure-inchikey> <structure-fingerprint>6004000008840000000080000000000000000204008000000000000000000000000000100000012000000000800000200000000000000000000000000000000000000000000008000000000000000000402400004000011000000000000000001000000001000000000000020010000080000002010000000000000000000000080000004000000000401000200000400080000000200000000000000000000000000000000000000004000008000000000200008008000000a100000002000100000000200080000000000000400000000000000000800020000200000000010000000000008001000040000000010000a02000000000400002000000000000</structure-fingerprint> 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