141831 <common-name>Frespaciguat</common-name> <description>Frespaciguat is a compound with the chemical formula C27H22ClF5N6O3. With an average molecular weight of 608.95 g/mol, Frespaciguat is a heavy molecule.</description> <cas>2101645-33-2</cas> <pubchem-id nil="true"/> <chemical-formula>C27H22ClF5N6O3</chemical-formula> <weight nil="true"/> <appearance nil="true"/> <melting-point nil="true"/> <boiling-point nil="true"/> <density nil="true"/> <solubility nil="true"/> <specific-gravity nil="true"/> <flash-point nil="true"/> <vapour-pressure nil="true"/> <route-of-exposure nil="true"/> <target nil="true"/> <mechanism-of-toxicity nil="true"/> <metabolism nil="true"/> <toxicity nil="true"/> <lethaldose nil="true"/> <carcinogenicity nil="true"/> <use-source nil="true"/> <min-risk-level nil="true"/> <health-effects nil="true"/> <symptoms nil="true"/> <treatment nil="true"/> <created-at type="dateTime">2026-04-15T18:18:19Z</created-at> <updated-at type="dateTime">2026-05-14T20:49:34Z</updated-at> <interacting-proteins nil="true"/> <wikipedia nil="true"/> <uniprot-id nil="true"/> <kegg-compound-id nil="true"/> <omim-id nil="true"/> <chebi-id nil="true"/> <biocyc-id nil="true"/> <ctd-id nil="true"/> <stitch-id nil="true"/> <drugbank-id>DB21683</drugbank-id> <pdb-id nil="true"/> <actor-id nil="true"/> <organism nil="true"/> <export type="boolean">true</export> <metabolizing-proteins nil="true"/> <transporting-proteins nil="true"/> <moldb-smiles>C[C@]1(C(=O)NC2=NC(=NC(N)=C12)C1=NN(CCC(F)(F)C(F)(F)F)C2=CC(Cl)=CC=C12)C1=CC=C(CCC(O)=O)C=C1</moldb-smiles> <moldb-formula>C27H22ClF5N6O3</moldb-formula> <moldb-inchi>InChI=1S/C27H22ClF5N6O3/c1-25(14-5-2-13(3-6-14)4-9-18(40)41)19-21(34)35-23(36-22(19)37-24(25)42)20-16-8-7-15(28)12-17(16)39(38-20)11-10-26(29,30)27(31,32)33/h2-3,5-8,12H,4,9-11H2,1H3,(H,40,41)(H3,34,35,36,37,42)/t25-/m0/s1</moldb-inchi> <moldb-inchikey>BAFUFNSAYGCZIC-VWLOTQADSA-N</moldb-inchikey> <moldb-average-mass type="decimal">608.95</moldb-average-mass> <moldb-mono-mass type="decimal">608.1362071</moldb-mono-mass> <origin nil="true"/> <state nil="true"/> <logp nil="true"/> <hmdb-id 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<moldb-alogps-solubility nil="true"/> <kingdom nil="true"/> <superklass nil="true"/> <klass nil="true"/> <subklass nil="true"/> <paper-count type="integer">4</paper-count> <sync-id>CED0043311</sync-id> <structure-inchikey>BAFUFNSAYGCZIC-VWLOTQADSA-N</structure-inchikey> <structure-fingerprint>1040010000080000004200000800002044200000000008100000000000000000000022010000000004000200600000000000000000000000804000000000000000840000000000000000000002200000000000000400000000000000000000001008000000000400010000000000002010000000080000000000000000104084800000024000020000000400000100000000000000000100000002001000008080000400004000008c000000000200000045000000000000000000000000008000000000000000000000000000010080000000004c00220000000008000000000000001002040000000000400800000080000000000000000000002</structure-fingerprint> 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