141435 <common-name>Amsilarotene</common-name> <description>Amsilarotene belongs to the anilides, a subclass of benzene and substituted derivatives within the organic compounds. This benzenoid compound has the chemical formula C20H27NO3Si2 and an average molecular weight of 385.61 g/mol.</description> <cas>125973-56-0</cas> <pubchem-id>9800306</pubchem-id> <chemical-formula>C20H27NO3Si2</chemical-formula> <weight>385.6</weight> <appearance nil="true"/> <melting-point nil="true"/> <boiling-point nil="true"/> <density nil="true"/> <solubility nil="true"/> <specific-gravity nil="true"/> <flash-point nil="true"/> <vapour-pressure nil="true"/> <route-of-exposure nil="true"/> <target nil="true"/> <mechanism-of-toxicity nil="true"/> <metabolism nil="true"/> <toxicity nil="true"/> <lethaldose nil="true"/> <carcinogenicity nil="true"/> <use-source nil="true"/> <min-risk-level nil="true"/> <health-effects nil="true"/> <symptoms nil="true"/> <treatment nil="true"/> <created-at type="dateTime">2026-04-15T17:46:39Z</created-at> <updated-at type="dateTime">2026-08-20T06:27:57Z</updated-at> <interacting-proteins nil="true"/> <wikipedia nil="true"/> <uniprot-id nil="true"/> <kegg-compound-id nil="true"/> <omim-id nil="true"/> <chebi-id nil="true"/> <biocyc-id nil="true"/> <ctd-id nil="true"/> <stitch-id nil="true"/> <drugbank-id>DB21085</drugbank-id> <pdb-id nil="true"/> <actor-id nil="true"/> <organism nil="true"/> <export type="boolean">true</export> <metabolizing-proteins nil="true"/> <transporting-proteins nil="true"/> <moldb-smiles>C[Si](C)(C)C1=CC(=CC(=C1)C(=O)NC1=CC=C(C=C1)C(O)=O)[Si](C)(C)C</moldb-smiles> <moldb-formula>C20H27NO3Si2</moldb-formula> <moldb-inchi>InChI=1S/C20H27NO3Si2/c1-25(2,3)17-11-15(12-18(13-17)26(4,5)6)19(22)21-16-9-7-14(8-10-16)20(23)24/h7-13H,1-6H3,(H,21,22)(H,23,24)</moldb-inchi> <moldb-inchikey>VVTNSTLJOVCBDL-UHFFFAOYSA-N</moldb-inchikey> <moldb-average-mass type="decimal">385.61</moldb-average-mass> <moldb-mono-mass type="decimal">385.152946803</moldb-mono-mass> <origin nil="true"/> <state nil="true"/> <logp nil="true"/> <hmdb-id nil="true"/> <chembl-id nil="true"/> <chemspider-id nil="true"/> <structure-image-file-name nil="true"/> <structure-image-content-type nil="true"/> <structure-image-file-size type="integer" nil="true"/> <structure-image-updated-at type="dateTime" nil="true"/> <biodb-id nil="true"/> <synthesis-reference nil="true"/> <structure-image-caption nil="true"/> <chemdb-id>CHEM137328</chemdb-id> <dsstox-id nil="true"/> <toxcast-id nil="true"/> <stoff-ident-origin nil="true"/> <stoff-ident-id nil="true"/> <susdat-id nil="true"/> <iupac>4-[[3,5-bis(trimethylsilyl)benzoyl]amino]benzoic acid</iupac> <moldb-polar-surface-area nil="true"/> <moldb-refractivity nil="true"/> <moldb-polarizability nil="true"/> <moldb-rotatable-bond-count nil="true"/> <moldb-acceptor-count nil="true"/> <moldb-donor-count nil="true"/> <moldb-pka-strongest-acidic nil="true"/> <moldb-pka-strongest-basic nil="true"/> <moldb-physiological-charge nil="true"/> <moldb-number-of-rings nil="true"/> <moldb-alogps-logp nil="true"/> <moldb-alogps-logs nil="true"/> <moldb-alogps-solubility nil="true"/> <kingdom>Organic compounds</kingdom> <superklass>Benzenoids</superklass> <klass>Benzene and substituted derivatives</klass> <subklass>Anilides</subklass> <paper-count type="integer">1</paper-count> <sync-id>CED0063603</sync-id> <structure-inchikey>VVTNSTLJOVCBDL-UHFFFAOYSA-N</structure-inchikey> <structure-fingerprint>200000000000000000000100000000000000000800200000000000000200000000002004000000008000000080000002000000000000000000000000000000000000000020800000000000000000000000000000000000010000000010000000100000000000000000000000000000000000000000000040000400000000000004200080000000000000000000000000000000000000000000000000000000085000000000000000000000000000000000000000000010000000000000000000000000000000004000000000000200000000001000008000000000000040000000000400000000000000200000000000000000</structure-fingerprint> 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