141155 <common-name>Fasidotril</common-name> <description>Fasidotril is an organic compound with the chemical formula C23H25NO6S and an average molecular weight of 443.51 g/mol. Fasidotril belongs to the amino acids, peptides, and analogues, a subclass of carboxylic acids and derivatives within the organic compounds. In terms of its biological activity, one protein target has been recorded for this compound, which acts as a modulator of Neprilysin (MME).</description> <cas>135038-57-2</cas> <pubchem-id>5311337</pubchem-id> <chemical-formula>C23H25NO6S</chemical-formula> <weight>443.5</weight> <appearance nil="true"/> <melting-point nil="true"/> <boiling-point nil="true"/> <density nil="true"/> <solubility nil="true"/> <specific-gravity nil="true"/> <flash-point nil="true"/> <vapour-pressure nil="true"/> <route-of-exposure nil="true"/> <target nil="true"/> <mechanism-of-toxicity nil="true"/> <metabolism nil="true"/> <toxicity nil="true"/> <lethaldose nil="true"/> <carcinogenicity nil="true"/> <use-source nil="true"/> <min-risk-level nil="true"/> <health-effects nil="true"/> <symptoms nil="true"/> <treatment nil="true"/> <created-at type="dateTime">2026-04-15T17:25:01Z</created-at> <updated-at type="dateTime">2026-08-22T00:43:36Z</updated-at> <interacting-proteins nil="true"/> <wikipedia nil="true"/> <uniprot-id nil="true"/> <kegg-compound-id nil="true"/> <omim-id nil="true"/> <chebi-id nil="true"/> <biocyc-id nil="true"/> <ctd-id nil="true"/> <stitch-id nil="true"/> <drugbank-id>DB20511</drugbank-id> <pdb-id nil="true"/> <actor-id nil="true"/> <organism nil="true"/> <export type="boolean">true</export> <metabolizing-proteins nil="true"/> <transporting-proteins nil="true"/> <moldb-smiles>C[C@H](NC(=O)[C@@H](CSC(C)=O)CC1=CC2=C(OCO2)C=C1)C(=O)OCC1=CC=CC=C1</moldb-smiles> <moldb-formula>C23H25NO6S</moldb-formula> <moldb-inchi>InChI=1S/C23H25NO6S/c1-15(23(27)28-12-17-6-4-3-5-7-17)24-22(26)19(13-31-16(2)25)10-18-8-9-20-21(11-18)30-14-29-20/h3-9,11,15,19H,10,12-14H2,1-2H3,(H,24,26)/t15-,19+/m0/s1</moldb-inchi> <moldb-inchikey>KKBIUAUSZKGNOA-HNAYVOBHSA-N</moldb-inchikey> <moldb-average-mass type="decimal">443.51</moldb-average-mass> <moldb-mono-mass type="decimal">443.140258703</moldb-mono-mass> <origin nil="true"/> <state nil="true"/> <logp>3.5</logp> <hmdb-id nil="true"/> <chembl-id nil="true"/> <chemspider-id nil="true"/> <structure-image-file-name nil="true"/> <structure-image-content-type nil="true"/> <structure-image-file-size type="integer" nil="true"/> <structure-image-updated-at type="dateTime" nil="true"/> <biodb-id nil="true"/> <synthesis-reference nil="true"/> <structure-image-caption nil="true"/> <chemdb-id>CHEM137048</chemdb-id> <dsstox-id nil="true"/> <toxcast-id nil="true"/> <stoff-ident-origin nil="true"/> <stoff-ident-id nil="true"/> <susdat-id nil="true"/> <iupac>benzyl (2S)-2-[[(2S)-2-(acetylsulfanylmethyl)-3-(1,3-benzodioxol-5-yl)propanoyl]amino]propanoate</iupac> <moldb-polar-surface-area nil="true"/> <moldb-refractivity nil="true"/> <moldb-polarizability nil="true"/> <moldb-rotatable-bond-count nil="true"/> <moldb-acceptor-count nil="true"/> <moldb-donor-count nil="true"/> <moldb-pka-strongest-acidic nil="true"/> <moldb-pka-strongest-basic nil="true"/> <moldb-physiological-charge nil="true"/> <moldb-number-of-rings nil="true"/> <moldb-alogps-logp nil="true"/> <moldb-alogps-logs nil="true"/> <moldb-alogps-solubility nil="true"/> <kingdom>Organic compounds</kingdom> <superklass>Organic acids and derivatives</superklass> <klass>Carboxylic acids and derivatives</klass> <subklass>Amino acids, peptides, and analogues</subklass> <paper-count type="integer">40</paper-count> <sync-id>CED0024862</sync-id> <structure-inchikey>KKBIUAUSZKGNOA-HNAYVOBHSA-N</structure-inchikey> <structure-fingerprint>40000000000000000001800000000c00000010000000000000000000000000002000801000000200000000000000000004000000000000400000080000000000000000000000000400000000000000000020800000000100001000002040000080000000010000000000000000100000000000020000000080000004800000400010000040200000840000000000000080008000000100000000000000000000000000000000000014000000080000000000000000000000000000000020000000000000000000000000000040010000000004100000000000000220000000000080000000000000010044000000402400000000000000000200000000000020</structure-fingerprint> <structure-pattern-fingerprint>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</structure-pattern-fingerprint> <structure-pickle>ï¾­Þ��������������������!���€���`������ 4��������h��������(�������(������ 4��������`������� ������(�������`�������(�������`������@(������@h�������@(������@(�������(�������`�������(������@h�������@h��������(�������(�������(�������`������@(������@h�������@h�������@h�������@h�������@h��������������� ��(�������������� �� ��������� h� �h���h��� ��������h���h������(��� ��������h���h���h���h���h���h���h��� B����� ����������������������������</structure-pickle> <structure-indexed-at type="dateTime">2026-09-19T04:51:53Z</structure-indexed-at> </compound>