140052 <common-name>AVL-3288</common-name> <description>AVL-3288 is an organic compound with the formula C19H15Cl2N3O2 and an average molecular weight of 388.25 g/mol. AVL-3288 belongs to the anilides, a subclass of benzene and substituted derivatives within the organic compounds. In terms of its biological activity, it is recorded as a modulator of the neuronal acetylcholine receptor subunit alpha-7 (CHRNA7).</description> <cas>917837-54-8</cas> <pubchem-id>16005981</pubchem-id> <chemical-formula>C19H15Cl2N3O2</chemical-formula> <weight>388.2</weight> <appearance nil="true"/> <melting-point nil="true"/> <boiling-point nil="true"/> <density nil="true"/> <solubility nil="true"/> <specific-gravity nil="true"/> <flash-point nil="true"/> <vapour-pressure nil="true"/> <route-of-exposure nil="true"/> <target nil="true"/> <mechanism-of-toxicity nil="true"/> <metabolism nil="true"/> <toxicity nil="true"/> <lethaldose nil="true"/> <carcinogenicity nil="true"/> <use-source nil="true"/> <min-risk-level nil="true"/> <health-effects nil="true"/> <symptoms nil="true"/> <treatment nil="true"/> <created-at type="dateTime">2026-04-15T16:05:27Z</created-at> <updated-at type="dateTime">2026-08-20T01:57:42Z</updated-at> <interacting-proteins nil="true"/> <wikipedia nil="true"/> <uniprot-id nil="true"/> <kegg-compound-id nil="true"/> <omim-id nil="true"/> <chebi-id nil="true"/> <biocyc-id nil="true"/> <ctd-id nil="true"/> <stitch-id nil="true"/> <drugbank-id>DB18707</drugbank-id> <pdb-id nil="true"/> <actor-id nil="true"/> <organism nil="true"/> <export type="boolean">true</export> <metabolizing-proteins nil="true"/> <transporting-proteins nil="true"/> <moldb-smiles>CC1=NOC(=C1)C(=C\NC1=CC=C(Cl)C=C1)\C(=O)NC1=CC=C(Cl)C=C1</moldb-smiles> <moldb-formula>C19H15Cl2N3O2</moldb-formula> <moldb-inchi>InChI=1S/C19H15Cl2N3O2/c1-12-10-18(26-24-12)17(11-22-15-6-2-13(20)3-7-15)19(25)23-16-8-4-14(21)5-9-16/h2-11,22H,1H3,(H,23,25)/b17-11-</moldb-inchi> <moldb-inchikey>VMAKIACTLSBBIY-BOPFTXTBSA-N</moldb-inchikey> <moldb-average-mass type="decimal">388.25</moldb-average-mass> <moldb-mono-mass type="decimal">387.0541321</moldb-mono-mass> <origin nil="true"/> <state nil="true"/> <logp>4.1</logp> <hmdb-id nil="true"/> <chembl-id nil="true"/> <chemspider-id nil="true"/> <structure-image-file-name nil="true"/> <structure-image-content-type nil="true"/> <structure-image-file-size type="integer" nil="true"/> <structure-image-updated-at type="dateTime" nil="true"/> <biodb-id nil="true"/> <synthesis-reference nil="true"/> <structure-image-caption nil="true"/> <chemdb-id>CHEM135945</chemdb-id> <dsstox-id nil="true"/> <toxcast-id nil="true"/> <stoff-ident-origin nil="true"/> <stoff-ident-id nil="true"/> <susdat-id nil="true"/> <iupac>(2Z)-N-(4-chlorophenyl)-3-[(4-chlorophenyl)amino]-2-(3-methyl-1,2-oxazol-5-yl)prop-2-enamide</iupac> <moldb-polar-surface-area nil="true"/> <moldb-refractivity nil="true"/> <moldb-polarizability nil="true"/> <moldb-rotatable-bond-count nil="true"/> <moldb-acceptor-count nil="true"/> <moldb-donor-count nil="true"/> <moldb-pka-strongest-acidic nil="true"/> <moldb-pka-strongest-basic nil="true"/> <moldb-physiological-charge nil="true"/> <moldb-number-of-rings nil="true"/> <moldb-alogps-logp nil="true"/> <moldb-alogps-logs nil="true"/> <moldb-alogps-solubility nil="true"/> <kingdom>Organic compounds</kingdom> <superklass>Benzenoids</superklass> <klass>Benzene and substituted derivatives</klass> <subklass>Anilides</subklass> <paper-count type="integer">72</paper-count> <sync-id>CED0021070</sync-id> <structure-inchikey>VMAKIACTLSBBIY-BOPFTXTBSA-N</structure-inchikey> <structure-fingerprint>8000000000000000000000400000000000000000000001000000c0000000800000000000000000000000000000002000000000000000000000000080000000000000100000400000000000000000000220800000080240000000000000000000000000010080000010000000100000000000000000000000000000000000000000000040020400000100000000000080000000004000200400000000000000000000000000000000000000088000000000000000000000000000000000000002000000000000000000000000000080000010000000002010000220000000000000008000000000000040000000000400000000000000000000000000080000</structure-fingerprint> 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