139151 <common-name>Navuridine</common-name> <description>Navuridine is an organic compound with the formula C9H11N5O4 and an average molecular weight of 253.22 g/mol. Navuridine belongs to the pyrimidine 2',3'-dideoxyribonucleosides, a subclass of pyrimidine nucleosides within the organic compounds. In terms of its biological activity, it is recorded as an inhibitor of the Gag-Pol polyprotein (gag-pol).</description> <cas>84472-85-5</cas> <pubchem-id>55262</pubchem-id> <chemical-formula>C9H11N5O4</chemical-formula> <weight>253.22</weight> <appearance nil="true"/> <melting-point nil="true"/> <boiling-point nil="true"/> <density nil="true"/> <solubility nil="true"/> <specific-gravity nil="true"/> <flash-point nil="true"/> <vapour-pressure nil="true"/> <route-of-exposure nil="true"/> <target nil="true"/> <mechanism-of-toxicity nil="true"/> <metabolism nil="true"/> <toxicity nil="true"/> <lethaldose nil="true"/> <carcinogenicity nil="true"/> <use-source nil="true"/> <min-risk-level nil="true"/> <health-effects nil="true"/> <symptoms nil="true"/> <treatment nil="true"/> <created-at type="dateTime">2026-04-14T21:41:03Z</created-at> <updated-at type="dateTime">2026-08-25T09:07:25Z</updated-at> <interacting-proteins nil="true"/> <wikipedia nil="true"/> <uniprot-id nil="true"/> <kegg-compound-id nil="true"/> <omim-id nil="true"/> <chebi-id nil="true"/> <biocyc-id nil="true"/> <ctd-id nil="true"/> <stitch-id nil="true"/> <drugbank-id>DB17759</drugbank-id> <pdb-id nil="true"/> <actor-id nil="true"/> <organism nil="true"/> <export type="boolean">true</export> <metabolizing-proteins nil="true"/> <transporting-proteins nil="true"/> <moldb-smiles>OC[C@H]1O[C@H](C[C@@H]1N=[N+]=[N-])N1C=CC(=O)NC1=O</moldb-smiles> <moldb-formula>C9H11N5O4</moldb-formula> <moldb-inchi>InChI=1S/C9H11N5O4/c10-13-12-5-3-8(18-6(5)4-15)14-2-1-7(16)11-9(14)17/h1-2,5-6,8,15H,3-4H2,(H,11,16,17)/t5-,6-,8-/m1/s1</moldb-inchi> <moldb-inchikey>ZSNNBSPEFVIUDS-SHYZEUOFSA-N</moldb-inchikey> <moldb-average-mass type="decimal">253.218</moldb-average-mass> <moldb-mono-mass type="decimal">253.081103854</moldb-mono-mass> <origin nil="true"/> <state nil="true"/> <logp>-0.69</logp> <hmdb-id nil="true"/> <chembl-id nil="true"/> <chemspider-id nil="true"/> <structure-image-file-name nil="true"/> <structure-image-content-type nil="true"/> <structure-image-file-size type="integer" nil="true"/> <structure-image-updated-at type="dateTime" nil="true"/> <biodb-id nil="true"/> <synthesis-reference nil="true"/> <structure-image-caption nil="true"/> <chemdb-id>CHEM135044</chemdb-id> <dsstox-id nil="true"/> <toxcast-id nil="true"/> <stoff-ident-origin nil="true"/> <stoff-ident-id nil="true"/> <susdat-id nil="true"/> <iupac>1-[(2R,4S,5S)-4-azido-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione</iupac> <moldb-polar-surface-area nil="true"/> <moldb-refractivity nil="true"/> <moldb-polarizability nil="true"/> <moldb-rotatable-bond-count nil="true"/> <moldb-acceptor-count nil="true"/> <moldb-donor-count nil="true"/> <moldb-pka-strongest-acidic nil="true"/> <moldb-pka-strongest-basic nil="true"/> <moldb-physiological-charge nil="true"/> <moldb-number-of-rings nil="true"/> <moldb-alogps-logp nil="true"/> <moldb-alogps-logs nil="true"/> <moldb-alogps-solubility nil="true"/> <kingdom>Organic compounds</kingdom> <superklass>Nucleosides, nucleotides, and analogues</superklass> <klass>Pyrimidine nucleosides</klass> <subklass>Pyrimidine 2',3'-dideoxyribonucleosides</subklass> <paper-count type="integer">61</paper-count> <sync-id>CED0022117</sync-id> <structure-inchikey>ZSNNBSPEFVIUDS-SHYZEUOFSA-N</structure-inchikey> <structure-fingerprint>8000000000000000000c20000000000200000000000000000000002000000000000000000000020000000000000000000000000000000000000000001000000000000000000080040000000200000000020800000000000000004000800020000000000010000000000000000000000000000020100000000000000000000100000000000000000000400200000000000000000800000000000000000000020020800000000800000000000080000400000000000400100000000000008200000000000000010000010000000000000000000000000000000004200080000000000001000020000000040000000000040000000000000040000800000000000</structure-fingerprint> <structure-pattern-fingerprint>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</structure-pattern-fingerprint> <structure-pickle type="binary" encoding="base64">776t3gAAAAAQAAAAAwAAAAAAAAASAAAAEwAAAIABCABgAAAAAQEGAGAAAAAC AgYgNAAAAAEBBAgAIAAAAAIGIDQAAAACAQQGAGAAAAACAgYgNAAAAAIBBAcA KAAAAAMDByAqAAAAAQIEByAqAAAA/wMCB0AoAAAAAwMGQGgAAAADAwEGQGgA AAADAwEGQCgAAAADBAgAKAAAAAMCB0A4AAAAAwEDBkAoAAAAAwQIACgAAAAD AgsAAQABAgACAwADBAAEBQAFBgAGBwAHCCgCCAkoAgQKAAoLaAwLDGgMDA1o DA0OKAIND2gMDxBoDBARKAIGAgAQCmgMQgIAAAAFAgMEBQYGCwwNDxAKFwQA AAAAAAAAFg== </structure-pickle> <structure-indexed-at type="dateTime">2026-09-19T04:50:55Z</structure-indexed-at> </compound>