137802 <common-name>MK-0773</common-name> <description>MK-0773 is an organic compound with the chemical formula C27H34FN5O2 and an average molecular weight of 479.60 g/mol. MK-0773 belongs to the androstane steroids, a subclass of steroids and steroid derivatives within the organic compounds. In terms of its biological activity, it is recorded as a modulator of the androgen receptor (AR).</description> <cas>606101-58-0</cas> <pubchem-id>11950726</pubchem-id> <chemical-formula>C27H34FN5O2</chemical-formula> <weight>479.6</weight> <appearance nil="true"/> <melting-point nil="true"/> <boiling-point nil="true"/> <density nil="true"/> <solubility nil="true"/> <specific-gravity nil="true"/> <flash-point nil="true"/> <vapour-pressure nil="true"/> <route-of-exposure nil="true"/> <target nil="true"/> <mechanism-of-toxicity nil="true"/> <metabolism nil="true"/> <toxicity nil="true"/> <lethaldose nil="true"/> <carcinogenicity nil="true"/> <use-source nil="true"/> <min-risk-level nil="true"/> <health-effects nil="true"/> <symptoms nil="true"/> <treatment nil="true"/> <created-at type="dateTime">2026-04-14T20:41:38Z</created-at> <updated-at type="dateTime">2026-08-22T07:35:37Z</updated-at> <interacting-proteins nil="true"/> <wikipedia nil="true"/> <uniprot-id nil="true"/> <kegg-compound-id nil="true"/> <omim-id nil="true"/> <chebi-id nil="true"/> <biocyc-id nil="true"/> <ctd-id nil="true"/> <stitch-id nil="true"/> <drugbank-id>DB16244</drugbank-id> <pdb-id nil="true"/> <actor-id nil="true"/> <organism nil="true"/> <export type="boolean">true</export> <metabolizing-proteins nil="true"/> <transporting-proteins nil="true"/> <moldb-smiles>[H][C@@]12CC[C@H](C(=O)NCC3=NC4=C(N3)C=CC=N4)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC[C@@]2([H])N(C)C(=O)C(F)=C[C@]12C</moldb-smiles> <moldb-formula>C27H34FN5O2</moldb-formula> <moldb-inchi>InChI=1S/C27H34FN5O2/c1-26-11-10-17-15(6-9-21-27(17,2)13-19(28)25(35)33(21)3)16(26)7-8-18(26)24(34)30-14-22-31-20-5-4-12-29-23(20)32-22/h4-5,12-13,15-18,21H,6-11,14H2,1-3H3,(H,30,34)(H,29,31,32)/t15-,16-,17-,18+,21+,26-,27+/m0/s1</moldb-inchi> <moldb-inchikey>GBEUKTWTUSPHEE-JWJWXJQQSA-N</moldb-inchikey> <moldb-average-mass type="decimal">479.6</moldb-average-mass> <moldb-mono-mass type="decimal">479.269653518</moldb-mono-mass> <origin nil="true"/> <state nil="true"/> <logp>2.36</logp> <hmdb-id nil="true"/> <chembl-id nil="true"/> <chemspider-id nil="true"/> <structure-image-file-name nil="true"/> <structure-image-content-type nil="true"/> <structure-image-file-size type="integer" nil="true"/> <structure-image-updated-at type="dateTime" nil="true"/> <biodb-id nil="true"/> <synthesis-reference nil="true"/> <structure-image-caption nil="true"/> <chemdb-id>CHEM133695</chemdb-id> <dsstox-id nil="true"/> <toxcast-id nil="true"/> <stoff-ident-origin nil="true"/> <stoff-ident-id nil="true"/> <susdat-id nil="true"/> <iupac>(4aS,4bS,6aS,7S,9aS,9bS,11aR)-3-fluoro-N-({1H-imidazo[4,5-b]pyridin-2-yl}methyl)-1,4a,6a-trimethyl-2-oxo-1H,2H,4aH,4bH,5H,6H,6aH,7H,8H,9H,9aH,9bH,10H,11H,11aH-indeno[5,4-f]quinoline-7-carboxamide</iupac> <moldb-polar-surface-area nil="true"/> <moldb-refractivity nil="true"/> <moldb-polarizability nil="true"/> <moldb-rotatable-bond-count nil="true"/> <moldb-acceptor-count nil="true"/> <moldb-donor-count nil="true"/> <moldb-pka-strongest-acidic nil="true"/> <moldb-pka-strongest-basic nil="true"/> <moldb-physiological-charge nil="true"/> <moldb-number-of-rings nil="true"/> <moldb-alogps-logp nil="true"/> <moldb-alogps-logs nil="true"/> <moldb-alogps-solubility nil="true"/> <kingdom>Organic compounds</kingdom> <superklass>Lipids and lipid-like molecules</superklass> <klass>Steroids and steroid derivatives</klass> <subklass>Androstane steroids</subklass> <paper-count type="integer">116</paper-count> <sync-id>CED0018173</sync-id> <structure-inchikey>GBEUKTWTUSPHEE-JWJWXJQQSA-N</structure-inchikey> <structure-fingerprint>900000400180000002008000000224020000000000010000000000000020000100000000002000000000000400008000000000000000012040000000200000000080000210000820000000004010000800000004000000000000210000000000000000030000000000020100000000000000000000100000100048000000a10000200000004080200000000000000000000000000020000001000004000000080000080001000000000001080000040000000000000000000000800000000000000000000000000000080000020000004200800001000000000000800001002040000000000400800001000001400000000000000000</structure-fingerprint> <structure-pattern-fingerprint>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</structure-pattern-fingerprint> <structure-pickle type="binary" encoding="base64">776t3gAAAAAQAAAAAwAAAAAAAAAjAAAAKAAAAIABBiA0AAAAAgEEBgBgAAAA AgIGAGAAAAACAgYgNAAAAAIBBAYAKAAAAAMECAAoAAAAAwIHAGgAAAADAgEG AGAAAAACAgZAKAAAAAMEB0AoAAAAAwMGQCgAAAADBAZAKAAAAAMEB0A4AAAA AwEDBkBoAAAAAwMBBkBoAAAAAwMBBkBoAAAAAwMBB0AoAAAAAwMGICQAAAAB BAYAYAAAAAEDBgBgAAAAAgIGAGAAAAACAgYgNAAAAAEBBAYgNAAAAAEBBAYA YAAAAAICBgBgAAAAAgIGIDQAAAABAQQHACgAAAADAwYAYAAAAAEDBgAoAAAA AwQIACgAAAADAgYAKAAAAAMECQAgAAAAAQYAaAAAAAMDAQYgJAAAAAIEBgBg AAAAAQMLAAEAAQIAAgMAAwQABAUoAgQGIAYHAAcIAAgJaAwJCmgMCgtoDAsM aAwLDWgMDQ5oDA4PaAwPEGgMAxEAERIAERMAExQAFBUAFRYAFhcAFxgAGBkA GRoAGhsAGhwgHB0oAhweIB4fAB4gKAIgIQAhIgARAAAhFQAWAAAhGQAMCGgM EApoDEIGAAAABQEAEQMCBQkIDAsKBg0ODxAKCwYTFBUWABEGFxgZIRUWBhoc HiAhGRcEAAAAAAAAABY= </structure-pickle> <structure-indexed-at type="dateTime">2026-09-19T04:50:36Z</structure-indexed-at> </compound>