137791 <common-name>Milvexian</common-name> <description>Milvexian belongs to the macrolactams, a class of phenylpropanoids and polyketides within the organic compounds. It has the chemical formula C28H23Cl2F2N9O2. With an average molecular weight of 626.45 g/mol, Milvexian is a heavy molecule. In terms of biological activity, it is recorded as an inhibitor of Coagulation factor XI (F11).</description> <cas>1802425-99-5</cas> <pubchem-id>118277544</pubchem-id> <chemical-formula>C28H23Cl2F2N9O2</chemical-formula> <weight>626.4</weight> <appearance nil="true"/> <melting-point nil="true"/> <boiling-point nil="true"/> <density nil="true"/> <solubility nil="true"/> <specific-gravity nil="true"/> <flash-point nil="true"/> <vapour-pressure nil="true"/> <route-of-exposure nil="true"/> <target nil="true"/> <mechanism-of-toxicity nil="true"/> <metabolism nil="true"/> <toxicity nil="true"/> <lethaldose nil="true"/> <carcinogenicity nil="true"/> <use-source nil="true"/> <min-risk-level nil="true"/> <health-effects nil="true"/> <symptoms nil="true"/> <treatment nil="true"/> <created-at type="dateTime">2026-04-14T20:41:10Z</created-at> <updated-at type="dateTime">2026-08-22T08:07:13Z</updated-at> <interacting-proteins nil="true"/> <wikipedia nil="true"/> <uniprot-id nil="true"/> <kegg-compound-id nil="true"/> <omim-id nil="true"/> <chebi-id nil="true"/> <biocyc-id nil="true"/> <ctd-id nil="true"/> <stitch-id nil="true"/> <drugbank-id>DB16233</drugbank-id> <pdb-id nil="true"/> <actor-id nil="true"/> <organism nil="true"/> <export type="boolean">true</export> <metabolizing-proteins nil="true"/> <transporting-proteins nil="true"/> <moldb-smiles>C[C@@H]1CCC[C@H](N2C=NC(=CC2=O)C2=CC(Cl)=CC=C2N2C=C(Cl)N=N2)C2=CC(=CC=N2)C2=C(NC1=O)C=NN2C(F)F</moldb-smiles> <moldb-formula>C28H23Cl2F2N9O2</moldb-formula> <moldb-inchi>InChI=1S/C28H23Cl2F2N9O2/c1-15-3-2-4-23(20-9-16(7-8-33-20)26-21(36-27(15)43)12-35-41(26)28(31)32)39-14-34-19(11-25(39)42)18-10-17(29)5-6-22(18)40-13-24(30)37-38-40/h5-15,23,28H,2-4H2,1H3,(H,36,43)/t15-,23+/m1/s1</moldb-inchi> <moldb-inchikey>FSWFYCYPTDLKON-CMJOXMDJSA-N</moldb-inchikey> <moldb-average-mass type="decimal">626.45</moldb-average-mass> <moldb-mono-mass type="decimal">625.1319827</moldb-mono-mass> <origin nil="true"/> <state nil="true"/> <logp>4.72</logp> <hmdb-id nil="true"/> <chembl-id nil="true"/> <chemspider-id nil="true"/> <structure-image-file-name nil="true"/> <structure-image-content-type nil="true"/> <structure-image-file-size type="integer" nil="true"/> <structure-image-updated-at type="dateTime" nil="true"/> <biodb-id nil="true"/> <synthesis-reference nil="true"/> <structure-image-caption nil="true"/> <chemdb-id>CHEM133684</chemdb-id> <dsstox-id nil="true"/> <toxcast-id nil="true"/> <stoff-ident-origin nil="true"/> <stoff-ident-id nil="true"/> <susdat-id nil="true"/> <iupac>(9R,13S)-13-{4-[5-chloro-2-(4-chloro-1H-1,2,3-triazol-1-yl)phenyl]-6-oxo-1,6-dihydropyrimidin-1-yl}-3-(difluoromethyl)-9-methyl-3,4,7,15-tetraazatricyclo[12.3.1.0^{2,6}]octadeca-1(17),2(6),4,14(18),15-pentaen-8-one</iupac> <moldb-polar-surface-area nil="true"/> <moldb-refractivity nil="true"/> <moldb-polarizability nil="true"/> <moldb-rotatable-bond-count nil="true"/> <moldb-acceptor-count nil="true"/> <moldb-donor-count nil="true"/> <moldb-pka-strongest-acidic nil="true"/> <moldb-pka-strongest-basic nil="true"/> <moldb-physiological-charge nil="true"/> <moldb-number-of-rings nil="true"/> <moldb-alogps-logp nil="true"/> <moldb-alogps-logs nil="true"/> <moldb-alogps-solubility nil="true"/> <kingdom>Organic compounds</kingdom> <superklass>Phenylpropanoids and polyketides</superklass> <klass>Macrolactams</klass> <subklass nil="true"/> <paper-count type="integer">292</paper-count> <sync-id>CED0013399</sync-id> <structure-inchikey>FSWFYCYPTDLKON-CMJOXMDJSA-N</structure-inchikey> 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"# #$(�!%h�%&h�&'h�'(�()�(*�#����h�� h���h���h�' h�B������#"! ���������� �������� ��������������%! '&����������</structure-pickle> <structure-indexed-at type="dateTime">2026-09-19T04:50:35Z</structure-indexed-at> </compound>