137047 <common-name>Reldesemtiv</common-name> <description>Reldesemtiv is an organic compound with the formula C19H18F2N6O and an average molecular weight of 384.39 g/mol. Reldesemtiv belongs to the pyrrole carboxylic acids and derivatives, a subclass of pyrroles within the organic compounds. It is further classified as an organoheterocyclic compound. Regarding its biological activity, one protein target has been recorded for this compound, as it acts as a modulator of Troponin C, skeletal muscle (TNNC2).</description> <cas>1345410-31-2</cas> <pubchem-id nil="true"/> <chemical-formula>C19H18F2N6O</chemical-formula> <weight nil="true"/> <appearance nil="true"/> <melting-point nil="true"/> <boiling-point nil="true"/> <density nil="true"/> <solubility nil="true"/> <specific-gravity nil="true"/> <flash-point nil="true"/> <vapour-pressure nil="true"/> <route-of-exposure nil="true"/> <target nil="true"/> <mechanism-of-toxicity nil="true"/> <metabolism nil="true"/> <toxicity nil="true"/> <lethaldose nil="true"/> <carcinogenicity nil="true"/> <use-source nil="true"/> <min-risk-level nil="true"/> <health-effects nil="true"/> <symptoms nil="true"/> <treatment nil="true"/> <created-at type="dateTime">2026-04-14T20:11:51Z</created-at> <updated-at type="dateTime">2026-05-14T19:49:37Z</updated-at> <interacting-proteins nil="true"/> <wikipedia nil="true"/> <uniprot-id nil="true"/> <kegg-compound-id nil="true"/> <omim-id nil="true"/> <chebi-id nil="true"/> <biocyc-id nil="true"/> <ctd-id nil="true"/> <stitch-id nil="true"/> <drugbank-id>DB15256</drugbank-id> <pdb-id nil="true"/> <actor-id nil="true"/> <organism nil="true"/> <export type="boolean">true</export> <metabolizing-proteins nil="true"/> <transporting-proteins nil="true"/> <moldb-smiles>NC(=O)C1=CN(C=C1)C1=CN=C(NC[C@@]2(C[C@H](F)C2)C2=NC=CC=C2F)N=C1</moldb-smiles> <moldb-formula>C19H18F2N6O</moldb-formula> <moldb-inchi>InChI=1S/C19H18F2N6O/c20-13-6-19(7-13,16-15(21)2-1-4-23-16)11-26-18-24-8-14(9-25-18)27-5-3-12(10-27)17(22)28/h1-5,8-10,13H,6-7,11H2,(H2,22,28)(H,24,25,26)/t13-,19-</moldb-inchi> <moldb-inchikey>MQXWPWOCXGARRK-HJGJAMNPSA-N</moldb-inchikey> <moldb-average-mass type="decimal">384.391</moldb-average-mass> <moldb-mono-mass type="decimal">384.15101555</moldb-mono-mass> <origin nil="true"/> <state nil="true"/> <logp>1.57</logp> <hmdb-id nil="true"/> <chembl-id nil="true"/> <chemspider-id nil="true"/> <structure-image-file-name nil="true"/> <structure-image-content-type nil="true"/> <structure-image-file-size type="integer" nil="true"/> <structure-image-updated-at type="dateTime" nil="true"/> <biodb-id nil="true"/> <synthesis-reference nil="true"/> <structure-image-caption nil="true"/> <chemdb-id>CHEM132940</chemdb-id> <dsstox-id nil="true"/> <toxcast-id nil="true"/> <stoff-ident-origin nil="true"/> <stoff-ident-id nil="true"/> <susdat-id nil="true"/> <iupac>1-[2-({[(1r,3r)-3-fluoro-1-(3-fluoropyridin-2-yl)cyclobutyl]methyl}amino)pyrimidin-5-yl]-1H-pyrrole-3-carboxamide</iupac> <moldb-polar-surface-area nil="true"/> <moldb-refractivity nil="true"/> <moldb-polarizability nil="true"/> <moldb-rotatable-bond-count nil="true"/> <moldb-acceptor-count nil="true"/> <moldb-donor-count nil="true"/> <moldb-pka-strongest-acidic nil="true"/> <moldb-pka-strongest-basic nil="true"/> <moldb-physiological-charge nil="true"/> <moldb-number-of-rings nil="true"/> <moldb-alogps-logp nil="true"/> <moldb-alogps-logs nil="true"/> <moldb-alogps-solubility nil="true"/> <kingdom>Organic compounds</kingdom> <superklass>Organoheterocyclic compounds</superklass> <klass>Pyrroles</klass> <subklass>Pyrrole carboxylic acids and derivatives</subklass> <paper-count type="integer">92</paper-count> <sync-id>CED0019465</sync-id> <structure-inchikey>MQXWPWOCXGARRK-HJGJAMNPSA-N</structure-inchikey> <structure-fingerprint>800000000000800000000000100800000000000000000010080000000000000000100400000000000000002000000000000000008200800008000000040000009000000000000000000000000020000001000010000000000000000000000000810000004000000000000000000000020101100100000000000000100080100008000000800401000000000080001000000000000000000000000000080000000000000000000000084000000080000000080800000000000000000100000000000200000000000000000010000000000000002100000200000000000000010040008000002060000000000400800000000000000000000000000000</structure-fingerprint> 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