136143 <common-name>Selisistat</common-name> <description>Selisistat is an organic compound with the formula C13H13ClN2O and an average molecular weight of 248.71 g/mol. Selisistat belongs to the carbazoles, a subclass of indoles and derivatives within the organic compounds. In terms of biological activity, it is recorded as an inhibitor of the NAD-dependent protein deacetylase sirtuin-1 (SIRT1).</description> <cas>49843-98-3</cas> <pubchem-id>5113032</pubchem-id> <chemical-formula>C13H13ClN2O</chemical-formula> <weight>248.71</weight> <appearance nil="true"/> <melting-point nil="true"/> <boiling-point nil="true"/> <density nil="true"/> <solubility nil="true"/> <specific-gravity nil="true"/> <flash-point nil="true"/> <vapour-pressure nil="true"/> <route-of-exposure nil="true"/> <target nil="true"/> <mechanism-of-toxicity nil="true"/> <metabolism nil="true"/> <toxicity nil="true"/> <lethaldose nil="true"/> <carcinogenicity nil="true"/> <use-source nil="true"/> <min-risk-level nil="true"/> <health-effects nil="true"/> <symptoms nil="true"/> <treatment nil="true"/> <created-at type="dateTime">2026-04-14T19:36:56Z</created-at> <updated-at type="dateTime">2026-08-18T23:18:37Z</updated-at> <interacting-proteins nil="true"/> <wikipedia nil="true"/> <uniprot-id nil="true"/> <kegg-compound-id nil="true"/> <omim-id nil="true"/> <chebi-id nil="true"/> <biocyc-id nil="true"/> <ctd-id nil="true"/> <stitch-id nil="true"/> <drugbank-id>DB13978</drugbank-id> <pdb-id nil="true"/> <actor-id nil="true"/> <organism nil="true"/> <export type="boolean">true</export> <metabolizing-proteins nil="true"/> <transporting-proteins nil="true"/> <moldb-smiles>NC(=O)C1CCCC2=C1NC1=C2C=C(Cl)C=C1</moldb-smiles> <moldb-formula>C13H13ClN2O</moldb-formula> <moldb-inchi>InChI=1S/C13H13ClN2O/c14-7-4-5-11-10(6-7)8-2-1-3-9(13(15)17)12(8)16-11/h4-6,9,16H,1-3H2,(H2,15,17)</moldb-inchi> <moldb-inchikey>FUZYTVDVLBBXDL-UHFFFAOYSA-N</moldb-inchikey> <moldb-average-mass type="decimal">248.71</moldb-average-mass> <moldb-mono-mass type="decimal">248.0716407</moldb-mono-mass> <origin nil="true"/> <state nil="true"/> <logp>2.46</logp> <hmdb-id nil="true"/> <chembl-id nil="true"/> <chemspider-id nil="true"/> <structure-image-file-name nil="true"/> <structure-image-content-type nil="true"/> <structure-image-file-size type="integer" nil="true"/> <structure-image-updated-at type="dateTime" nil="true"/> <biodb-id nil="true"/> <synthesis-reference nil="true"/> <structure-image-caption nil="true"/> <chemdb-id>CHEM132036</chemdb-id> <dsstox-id nil="true"/> <toxcast-id nil="true"/> <stoff-ident-origin nil="true"/> <stoff-ident-id nil="true"/> <susdat-id nil="true"/> <iupac>6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide</iupac> <moldb-polar-surface-area nil="true"/> <moldb-refractivity nil="true"/> <moldb-polarizability nil="true"/> <moldb-rotatable-bond-count nil="true"/> <moldb-acceptor-count nil="true"/> <moldb-donor-count nil="true"/> <moldb-pka-strongest-acidic nil="true"/> <moldb-pka-strongest-basic nil="true"/> <moldb-physiological-charge nil="true"/> <moldb-number-of-rings nil="true"/> <moldb-alogps-logp nil="true"/> <moldb-alogps-logs nil="true"/> <moldb-alogps-solubility nil="true"/> <kingdom>Organic compounds</kingdom> <superklass>Organoheterocyclic compounds</superklass> <klass>Indoles and derivatives</klass> <subklass>Carbazoles</subklass> <paper-count type="integer">549</paper-count> <sync-id>CED0010706</sync-id> <structure-inchikey>FUZYTVDVLBBXDL-UHFFFAOYSA-N</structure-inchikey> <structure-fingerprint>100000800000400000000000080020000000000000000000000000000000040000000000000000000000000004000000000000000000000400000000000000000000020000000000000000040000000000000000000010080000000000000100000000000020000000000000000000000100800000000000000002000200000000000001000000000000000000000000000000010000004000008040000080100000000000000000080000000000000000000000000000000000000008000000080000012000000000200204200000000000000010000000000000040000000000400001000000000080000000000000000</structure-fingerprint> <structure-pattern-fingerprint>501002100902864080008844010828000180340211052004003560408200808c74220814168000000000510800c0800004204024e08c32410226643004a04000c4110c0812101c900090100003620200082005915301177262000522102058021c2804270048220020008400d4140200200680308109c40431192a2802510012024600194cd8820808061240aa2c0008393c881244c0348300220c8020c0008480c300000802c1000a000948017c2f1002c02000a953084818a0421808c242100001128404400a1301800004140502c004010008624050220d0002440a008100111008100001420400080411515a2000081022309242000e4008b08052000006</structure-pattern-fingerprint> <structure-pickle type="binary" encoding="base64">776t3gAAAAAQAAAAAwAAAAAAAAARAAAAEwAAAIABBwBoAAAAAwECBgAoAAAA AwQIACgAAAADAgYAYAAAAAMBBgBgAAAAAgIGAGAAAAACAgYAYAAAAAICBkAo AAAAAwQGQCgAAAADBAdAOAAAAAMBAwZAKAAAAAMEBkAoAAAAAwQGQGgAAAAD AwEGQCgAAAADBBEAIAAAAAEGQGgAAAADAwEGQGgAAAADAwELAAEgAQIoAgED AAMEAAQFAAUGAAYHAAcIaAwICWgMCQpoDAoLaAwLDGgMDA1oDA0OAA0PaAwP EGgMCAMAEApoDAsHaAxCAwAAAAYDCAcGBQQFCQgHCwoGDA0PEAoLFwQAAAAA AAAAFg== </structure-pickle> <structure-indexed-at type="dateTime">2026-09-19T04:49:54Z</structure-indexed-at> </compound>