136131 <common-name>2,5-Dimethoxy-4-ethylthioamphetamine</common-name> <description>2,5-Dimethoxy-4-ethylthioamphetamine belongs to the phenethylamines, a subclass of benzene and substituted derivatives within the organic compounds. This benzenoid compound has the chemical formula C13H21NO2S and an average molecular weight of 255.38 g/mol. In terms of its pharmacological profile, two protein targets have been recorded for this substance. It acts as an agonist of 5-hydroxytryptamine receptor 2A (HTR2A) and 5-hydroxytryptamine receptor 2C (HTR2C).</description> <cas>185562-00-9</cas> <pubchem-id nil="true"/> <chemical-formula>C13H21NO2S</chemical-formula> <weight nil="true"/> <appearance nil="true"/> <melting-point nil="true"/> <boiling-point nil="true"/> <density nil="true"/> <solubility nil="true"/> <specific-gravity nil="true"/> <flash-point nil="true"/> <vapour-pressure nil="true"/> <route-of-exposure nil="true"/> <target nil="true"/> <mechanism-of-toxicity nil="true"/> <metabolism nil="true"/> <toxicity nil="true"/> <lethaldose nil="true"/> <carcinogenicity nil="true"/> <use-source nil="true"/> <min-risk-level nil="true"/> <health-effects nil="true"/> <symptoms nil="true"/> <treatment nil="true"/> <created-at type="dateTime">2026-04-14T19:36:05Z</created-at> <updated-at type="dateTime">2026-05-14T19:38:42Z</updated-at> <interacting-proteins nil="true"/> <wikipedia nil="true"/> <uniprot-id nil="true"/> <kegg-compound-id nil="true"/> <omim-id nil="true"/> <chebi-id nil="true"/> <biocyc-id nil="true"/> <ctd-id nil="true"/> <stitch-id nil="true"/> <drugbank-id>DB13940</drugbank-id> <pdb-id nil="true"/> <actor-id nil="true"/> <organism nil="true"/> <export type="boolean">true</export> <metabolizing-proteins nil="true"/> <transporting-proteins nil="true"/> <moldb-smiles>CCSC1=CC(OC)=C(CC(C)N)C=C1OC</moldb-smiles> <moldb-formula>C13H21NO2S</moldb-formula> <moldb-inchi>InChI=1S/C13H21NO2S/c1-5-17-13-8-11(15-3)10(6-9(2)14)7-12(13)16-4/h7-9H,5-6,14H2,1-4H3</moldb-inchi> <moldb-inchikey>MCYCODJKXUJSAT-UHFFFAOYSA-N</moldb-inchikey> <moldb-average-mass type="decimal">255.38</moldb-average-mass> <moldb-mono-mass type="decimal">255.129300094</moldb-mono-mass> <origin nil="true"/> <state nil="true"/> <logp>2.37</logp> <hmdb-id nil="true"/> <chembl-id nil="true"/> <chemspider-id nil="true"/> <structure-image-file-name nil="true"/> <structure-image-content-type nil="true"/> <structure-image-file-size type="integer" nil="true"/> <structure-image-updated-at type="dateTime" nil="true"/> <biodb-id nil="true"/> <synthesis-reference nil="true"/> <structure-image-caption nil="true"/> <chemdb-id>CHEM132024</chemdb-id> <dsstox-id nil="true"/> <toxcast-id nil="true"/> <stoff-ident-origin nil="true"/> <stoff-ident-id nil="true"/> <susdat-id nil="true"/> <iupac>1-[4-(ethylsulfanyl)-2,5-dimethoxyphenyl]propan-2-amine</iupac> <moldb-polar-surface-area nil="true"/> <moldb-refractivity nil="true"/> <moldb-polarizability nil="true"/> <moldb-rotatable-bond-count nil="true"/> <moldb-acceptor-count nil="true"/> <moldb-donor-count nil="true"/> <moldb-pka-strongest-acidic nil="true"/> <moldb-pka-strongest-basic nil="true"/> <moldb-physiological-charge nil="true"/> <moldb-number-of-rings nil="true"/> <moldb-alogps-logp nil="true"/> <moldb-alogps-logs nil="true"/> <moldb-alogps-solubility nil="true"/> <kingdom>Organic compounds</kingdom> <superklass>Benzenoids</superklass> <klass>Benzene and substituted derivatives</klass> <subklass>Phenethylamines</subklass> <paper-count type="integer">1</paper-count> <sync-id>CED0067735</sync-id> <structure-inchikey>MCYCODJKXUJSAT-UHFFFAOYSA-N</structure-inchikey> <structure-fingerprint>40000000000000000001800000000800000000008400000000000000000000400000001002000000000004000000000000000000000000000000000000000000000000000000010000000000200400000000000000000100000000000000000000002000000008000040000000380000000000000000000000000000000100004000000040000000000000000000000000001000000000000000000000000000000000000000800004000000080000000000000000000000000000000000000080000000000000000000010000000080000000000000000000000000000000000000000000000000000040000000000000000000000020000000000000000000</structure-fingerprint> <structure-pattern-fingerprint>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</structure-pattern-fingerprint> <structure-pickle type="binary" encoding="base64">776t3gAAAAAQAAAAAwAAAAAAAAARAAAAEQAAAIABBgBgAAAAAQMGAGAAAAAC AhAAIAAAAAIGQCgAAAADBAZAaAAAAAMDAQZAKAAAAAMECAAoAAAAAwIGAGAA AAABAwZAKAAAAAMEBgBgAAAAAgIGAGAAAAADAQYAYAAAAAEDBwBgAAAAAQIG QGgAAAADAwEGQCgAAAADBAgAKAAAAAMCBgBgAAAAAQMLAAEAAQIAAgMAAwRo DAQFaAwFBiAGBwAFCGgMCAkACQoACgsACgwACA1oDA0OaAwODyAPEAAOA2gM QgEAAAAGAw4NCAUEFwQAAAAAAAAAFg== </structure-pickle> <structure-indexed-at type="dateTime">2026-09-19T04:49:53Z</structure-indexed-at> </compound>