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  <id type="integer">133852</id>
  <title nil="true"/>
  <common-name>Glesatinib</common-name>
  <description>Glesatinib is an organic compound with the chemical formula C31H27F2N5O3S2. Glesatinib belongs to the n-phenylthioureas, a subclass of benzene and substituted derivatives within the organic compounds. With an average molecular weight of 619.71 g/mol, Glesatinib is a heavy molecule. In terms of biological activity, Glesatinib acts as a modulator of the tyrosine-protein kinase receptor UFO (AXL).</description>
  <cas>936694-12-1</cas>
  <pubchem-id>25181472</pubchem-id>
  <chemical-formula>C31H27F2N5O3S2</chemical-formula>
  <weight>619.7</weight>
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  <boiling-point nil="true"/>
  <density nil="true"/>
  <solubility nil="true"/>
  <specific-gravity nil="true"/>
  <flash-point nil="true"/>
  <vapour-pressure nil="true"/>
  <route-of-exposure nil="true"/>
  <target nil="true"/>
  <mechanism-of-toxicity nil="true"/>
  <metabolism nil="true"/>
  <toxicity nil="true"/>
  <lethaldose nil="true"/>
  <carcinogenicity nil="true"/>
  <use-source nil="true"/>
  <min-risk-level nil="true"/>
  <health-effects nil="true"/>
  <symptoms nil="true"/>
  <treatment nil="true"/>
  <created-at type="dateTime">2026-04-14T16:06:49Z</created-at>
  <updated-at type="dateTime">2026-08-22T10:31:05Z</updated-at>
  <interacting-proteins nil="true"/>
  <wikipedia nil="true"/>
  <uniprot-id nil="true"/>
  <kegg-compound-id nil="true"/>
  <omim-id nil="true"/>
  <chebi-id nil="true"/>
  <biocyc-id nil="true"/>
  <ctd-id nil="true"/>
  <stitch-id nil="true"/>
  <drugbank-id>DB06302</drugbank-id>
  <pdb-id nil="true"/>
  <actor-id nil="true"/>
  <organism nil="true"/>
  <export type="boolean">true</export>
  <metabolizing-proteins nil="true"/>
  <transporting-proteins nil="true"/>
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  <moldb-formula>C31H27F2N5O3S2</moldb-formula>
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  <moldb-average-mass type="decimal">619.71</moldb-average-mass>
  <moldb-mono-mass type="decimal">619.152338423</moldb-mono-mass>
  <origin nil="true"/>
  <state nil="true"/>
  <logp>5.46</logp>
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  <chemdb-id>CHEM129745</chemdb-id>
  <dsstox-id nil="true"/>
  <toxcast-id nil="true"/>
  <stoff-ident-origin nil="true"/>
  <stoff-ident-id nil="true"/>
  <susdat-id nil="true"/>
  <iupac>3-(3-fluoro-4-{[2-(5-{[(2-methoxyethyl)amino]methyl}pyridin-2-yl)thieno[3,2-b]pyridin-7-yl]oxy}phenyl)-1-[2-(4-fluorophenyl)acetyl]thiourea</iupac>
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  <moldb-polarizability nil="true"/>
  <moldb-rotatable-bond-count nil="true"/>
  <moldb-acceptor-count nil="true"/>
  <moldb-donor-count nil="true"/>
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  <kingdom>Organic compounds</kingdom>
  <superklass>Benzenoids</superklass>
  <klass>Benzene and substituted derivatives</klass>
  <subklass>N-phenylthioureas</subklass>
  <paper-count type="integer">254</paper-count>
  <sync-id>CED0014090</sync-id>
  <structure-inchikey>YRCHYHRCBXNYNU-UHFFFAOYSA-N</structure-inchikey>
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  <structure-indexed-at type="dateTime">2026-09-19T04:49:19Z</structure-indexed-at>
</compound>
