133080 <common-name>Cycloleucine</common-name> <description>Cycloleucine is an organic compound with the formula C6H11NO2 and an average molecular weight of 129.16 g/mol. Cycloleucine belongs to the amino acids, peptides, and analogues, a subclass of carboxylic acids and derivatives within the organic compounds. Regarding its biological activity, the compound is a recorded inhibitor of the protein target Glutamate receptor ionotropic, NMDA 1 (GRIN1). Additionally, Cycloleucine has been found in or released from two recorded sources, specifically electrical and electronic equipment such as antennas and amplifiers.</description> <cas>52-52-8</cas> <pubchem-id>2901</pubchem-id> <chemical-formula>C6H11NO2</chemical-formula> <weight nil="true"/> <appearance nil="true"/> <melting-point nil="true"/> <boiling-point nil="true"/> <density nil="true"/> <solubility nil="true"/> <specific-gravity nil="true"/> <flash-point nil="true"/> <vapour-pressure nil="true"/> <route-of-exposure nil="true"/> <target nil="true"/> <mechanism-of-toxicity nil="true"/> <metabolism nil="true"/> <toxicity nil="true"/> <lethaldose nil="true"/> <carcinogenicity nil="true"/> <use-source nil="true"/> <min-risk-level nil="true"/> <health-effects nil="true"/> <symptoms nil="true"/> <treatment nil="true"/> <created-at type="dateTime">2026-04-14T15:16:24Z</created-at> <updated-at type="dateTime">2026-05-14T18:09:26Z</updated-at> <interacting-proteins nil="true"/> <wikipedia nil="true"/> <uniprot-id nil="true"/> <kegg-compound-id nil="true"/> <omim-id nil="true"/> <chebi-id nil="true"/> <biocyc-id nil="true"/> <ctd-id nil="true"/> <stitch-id nil="true"/> <drugbank-id>DB04620</drugbank-id> <pdb-id nil="true"/> <actor-id nil="true"/> <organism nil="true"/> <export type="boolean">true</export> <metabolizing-proteins nil="true"/> <transporting-proteins nil="true"/> <moldb-smiles>NC1(CCCC1)C(O)=O</moldb-smiles> <moldb-formula>C6H11NO2</moldb-formula> <moldb-inchi>InChI=1S/C6H11NO2/c7-6(5(8)9)3-1-2-4-6/h1-4,7H2,(H,8,9)</moldb-inchi> <moldb-inchikey>NILQLFBWTXNUOE-UHFFFAOYSA-N</moldb-inchikey> <moldb-average-mass type="decimal">129.157</moldb-average-mass> <moldb-mono-mass type="decimal">129.078978601</moldb-mono-mass> <origin nil="true"/> <state nil="true"/> <logp>-1.8</logp> <hmdb-id nil="true"/> <chembl-id nil="true"/> <chemspider-id nil="true"/> <structure-image-file-name nil="true"/> <structure-image-content-type nil="true"/> <structure-image-file-size type="integer" nil="true"/> <structure-image-updated-at type="dateTime" nil="true"/> <biodb-id nil="true"/> <synthesis-reference nil="true"/> <structure-image-caption nil="true"/> <chemdb-id>CHEM128973</chemdb-id> <dsstox-id nil="true"/> <toxcast-id nil="true"/> <stoff-ident-origin nil="true"/> <stoff-ident-id nil="true"/> <susdat-id nil="true"/> <iupac>1-aminocyclopentane-1-carboxylic acid</iupac> <moldb-polar-surface-area nil="true"/> <moldb-refractivity nil="true"/> <moldb-polarizability nil="true"/> <moldb-rotatable-bond-count nil="true"/> <moldb-acceptor-count nil="true"/> <moldb-donor-count nil="true"/> <moldb-pka-strongest-acidic nil="true"/> <moldb-pka-strongest-basic nil="true"/> <moldb-physiological-charge nil="true"/> <moldb-number-of-rings nil="true"/> <moldb-alogps-logp nil="true"/> <moldb-alogps-logs nil="true"/> <moldb-alogps-solubility nil="true"/> <kingdom>Organic compounds</kingdom> <superklass>Organic acids and derivatives</superklass> <klass>Carboxylic acids and derivatives</klass> <subklass>Amino acids, peptides, and analogues</subklass> <paper-count type="integer">842</paper-count> <sync-id>CED0009144</sync-id> <structure-inchikey>NILQLFBWTXNUOE-UHFFFAOYSA-N</structure-inchikey> <structure-fingerprint>80000000000000008000000000000000000000000000000000000000000000000004000000000000000000000000000000000000000000000000000000000000000020000000000000000200000000000000000000010000200000000000000000000000020000000000000000000000000800000008000000000000000000000000201000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002000000002000000000000000000000000000000000000000000000000000000000000000000000400000000000000000000000000004000</structure-fingerprint> <structure-pattern-fingerprint>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</structure-pattern-fingerprint> <structure-pickle type="binary" encoding="base64">776t3gAAAAAQAAAAAwAAAAAAAAAJAAAACQAAAIABBwBgAAAAAQIGACAAAAAE BgBgAAAAAgIGAGAAAAACAgYAYAAAAAICBgBgAAAAAgIGACgAAAADBAgAaAAA AAMBAQgAKAAAAAMCCwABAAECAAIDAAMEAAQFAAEGAAYHIAYIKAIFAQBCAQAA AAUBAgMEBRcEAAAAAAAAABY= </structure-pickle> <structure-indexed-at type="dateTime">2026-09-19T04:49:09Z</structure-indexed-at> </compound>