115546 <common-name>Dimemorfan</common-name> <description>Dimemorfan is an organic compound with the formula C18H25N and an average molecular weight of 255.41 g/mol. Dimemorfan belongs to the morphinans, a class of alkaloids and derivatives within the organic compounds. Regarding its biological activity, this compound is recorded as an agonist of the Sigma non-opioid intracellular receptor 1 (SIGMAR1). Dimemorfan has been identified in three recorded sources, all of which are household cleaning and consumer products. These sources include pipe accessories, other smoking requisites, and non electric simulated smoking devices.</description> <cas>36309-01-0</cas> <pubchem-id>3037918</pubchem-id> <chemical-formula>C18H25N</chemical-formula> <weight>255.4</weight> <appearance nil="true"/> <melting-point nil="true"/> <boiling-point nil="true"/> <density nil="true"/> <solubility nil="true"/> <specific-gravity nil="true"/> <flash-point nil="true"/> <vapour-pressure nil="true"/> <route-of-exposure nil="true"/> <target nil="true"/> <mechanism-of-toxicity nil="true"/> <metabolism nil="true"/> <toxicity nil="true"/> <lethaldose nil="true"/> <carcinogenicity nil="true"/> <use-source nil="true"/> <min-risk-level nil="true"/> <health-effects nil="true"/> <symptoms nil="true"/> <treatment nil="true"/> <created-at type="dateTime">2026-04-05T22:52:57Z</created-at> <updated-at type="dateTime">2026-08-20T01:05:02Z</updated-at> <interacting-proteins nil="true"/> <wikipedia nil="true"/> <uniprot-id nil="true"/> <kegg-compound-id nil="true"/> <omim-id nil="true"/> <chebi-id nil="true"/> <biocyc-id nil="true"/> <ctd-id nil="true"/> <stitch-id nil="true"/> <drugbank-id>DB13810</drugbank-id> <pdb-id nil="true"/> <actor-id nil="true"/> <organism nil="true"/> <export type="boolean">true</export> <metabolizing-proteins nil="true"/> <transporting-proteins nil="true"/> <moldb-smiles>CN1CC[C@@]23CCCC[C@@H]2[C@@H]1CC1=CC=C(C)C=C31</moldb-smiles> <moldb-formula>C18H25N</moldb-formula> <moldb-inchi>InChI=1/C18H25N/c1-13-6-7-14-12-17-15-5-3-4-8-18(15,16(14)11-13)9-10-19(17)2/h6-7,11,15,17H,3-5,8-10,12H2,1-2H3</moldb-inchi> <moldb-inchikey>KBEZZLAAKIIPFK-NJAFHUGGSA-N</moldb-inchikey> <moldb-average-mass type="decimal">255.405</moldb-average-mass> <moldb-mono-mass type="decimal">255.1986998</moldb-mono-mass> <origin nil="true"/> <state nil="true"/> <logp>4.16</logp> <hmdb-id nil="true"/> <chembl-id nil="true"/> <chemspider-id nil="true"/> <structure-image-file-name nil="true"/> <structure-image-content-type nil="true"/> <structure-image-file-size type="integer" nil="true"/> <structure-image-updated-at type="dateTime" nil="true"/> <biodb-id nil="true"/> <synthesis-reference nil="true"/> <structure-image-caption nil="true"/> <chemdb-id>CHEM111439</chemdb-id> <dsstox-id nil="true"/> <toxcast-id nil="true"/> <stoff-ident-origin nil="true"/> <stoff-ident-id nil="true"/> <susdat-id>NS00089284</susdat-id> <iupac>3,17-dimethylmorphinan</iupac> <moldb-polar-surface-area nil="true"/> <moldb-refractivity nil="true"/> <moldb-polarizability nil="true"/> <moldb-rotatable-bond-count nil="true"/> <moldb-acceptor-count nil="true"/> <moldb-donor-count nil="true"/> <moldb-pka-strongest-acidic nil="true"/> <moldb-pka-strongest-basic nil="true"/> <moldb-physiological-charge nil="true"/> <moldb-number-of-rings nil="true"/> <moldb-alogps-logp nil="true"/> <moldb-alogps-logs nil="true"/> <moldb-alogps-solubility nil="true"/> <kingdom>Organic compounds</kingdom> <superklass>Alkaloids and derivatives</superklass> <klass>Morphinans</klass> <subklass nil="true"/> <paper-count type="integer">93</paper-count> <sync-id>CED0019410</sync-id> <structure-inchikey>KBEZZLAAKIIPFK-NJAFHUGGSA-N</structure-inchikey> <structure-fingerprint>11000000000000000000000000000000000000000000004000000000000000002000000010000000000200008000000000000000000010000000000000000000080000000000000000000000000000000120020000000020108000000000000000004100800000068000000000000080000004000200000000000000040080000000000000000080004000000000000080000000000000000000000008000000000000000000000000000000000000002000000000000400000002010000202000000000000000100000000000040000000000000000000000000080000000000000000</structure-fingerprint> <structure-pattern-fingerprint>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</structure-pattern-fingerprint> <structure-pickle>ï¾­Þ������������������������€���`������� ������`�������`������ $�������`�������`�������`�������`������ 4������� 4��������`������@(������@h�������@h�������@(�������`������@h�������@(������������������������������� � � ������ h� �h���h������h���h� ����h� �����B������ �������� ������ � ���������������</structure-pickle> <structure-indexed-at type="dateTime">2026-09-19T04:43:51Z</structure-indexed-at> </compound>